Synthesis of degradants and impurities of rabeprazole

C. Hazarathaiah Yadav; Venkatesh Medarametla

doi:10.53730/ijhs.v5nS2.7572

Synthesis of degradants and impurities of rabeprazole

https://doi.org/10.53730/ijhs.v5nS2.7572

Authors

C. Hazarathaiah Yadav
info@anaxlab.com
Vel Tech Rangarajan Dr. Sagunthala R&D Institute of science and technology, 400 feet Outer Ring Road, Avadi, Chennai, Tamil Nadu 600062, India
Venkatesh Medarametla Vel Tech Rangarajan Dr. Sagunthala R&D Institute of science and technology, 400 feet Outer Ring Road, Avadi, Chennai, Tamil Nadu 600062, India

Keywords:

metabolite, impurities, rabeprazole, anti-ulcerative drug

Abstract

Rabeprazole is an antiulcer drug comes under the Pharmacological class (antisecretory compounds) which is Proton-pump inhibitor, and It's used for heartburn, acid reflux and GORD (gastro-oesophageal reflux disease). Rabeprazole is also used to prevent and treat stomach ulcers. We have observed some of the metabolite and impurities during the process of synthesis of Rabeprazole. The main aim of the present work is to synthesis and characterisation of impurities and metabolites.

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References

Ray, Purna C.; Mittapelli, Vasantha; Rohatgi, Amit; Tyagi, Om Dutt[Synthetic Communications, 2007, vol. 37, # 17, p. 2861 - 2868]

Radl, Stanislav; Klecan, Ondrej; Havlicek, Jaroslav[Journal of Heterocyclic Chemistry, 2006, vol. 43, # 6, p. 1447 - 1453]

Reddy, Ganta Madhusudhan; Mukkanti, Kaga; Bhaskar, Boluggodu Vijaya; Reddy, Padi Pratap[Synthetic Communications, 2009, vol. 39, # 2, p. 278 - 290]

DIPHARMA FRANCIS S.R.L. - EP1921075, 2008, A2

Pingili, R. Reddy; Jambula, M. Reddy; Ganta, M. Reddy; Ghanta, M. Reddy; Sajja; Sundaram; Boluggdu, V. Bhaskar[Pharmazie, 2005, vol. 60, # 11, p. 814 - 818]

Published

31-12-2021

How to Cite

Yadav, C. H., & Medarametla, V. (2021). Synthesis of degradants and impurities of rabeprazole. International Journal of Health Sciences, 5(S2), 475–483. https://doi.org/10.53730/ijhs.v5nS2.7572

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Issue

Vol. 5 No. S2 (2021)

Section

Peer Review Articles

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