Study of the effect of ethanol alcohols on yeasts and fungi isolated from the nail

https://doi.org/10.53730/ijhs.v6nS3.7590

Authors

  • Ihsan H. Khudhair Lect. Biology Dept. College of Science/University of Thi-Qar/Iraq
  • Attab K. Daeikh Dhi Qar Education Directorate

Keywords:

alcohols , ETOH, candida

Abstract

The excessive use of alcoholic such as ethanol at a 75%, which are locally by of companies, it result by using of materials as sterilizing in order to eliminate of microorganisms, as is the case result of the outbreak such Corona virus, has led to in resistance by some of microorganisms and fungi, and the resistant strains, especially skin infections or nail, as the current study, which included C. albicans, C. glabrata, C. krusei, Rhodotorula, and  A. flavus   showed the high resistance by  fungi to the alcohols, surgical,  joonand jood, which The reason for this may be due to the resistant fungi by use of alcohol and those excessively patients.

Downloads

Download data is not yet available.

References

Wisplinghoff H, Bischoff T, Tallent SM, Seifert H, Wenzel RP, Edmond MB. Nosocomial bloodstream infections in US hospitals: analysis of 24,179 cases from a prospective nationwide surveillance study. Clin Infect Dis Off Publ Infect Dis Soc Am. 2004 Aug 1; 39(3):309–17.

Kojic EM, Darouiche RO. Candida infections of medical devices. Clin Microbiol Rev. 2004 Apr; 17 (2):255–67. PMID: 15084500

Ramage G, Saville SP, Thomas DP, López-Ribot JL. Candida biofilms: an update. Eukaryot Cell. 2005 Apr; 4(4):633–8. PMID: 15821123

Walraven CJ, Lee SA. Antifungal lock therapy. Antimicrob Agents Chemother. 2013 Jan; 57(1):1–8. doi: 10.1128/AAC.01351-12 PMID: 23070153

Chandra J, McCormick TS, Imamura Y, Mukherjee PK, Ghannoum MA. Interaction of Candida albicans with Adherent Human Peripheral Blood Mononuclear Cells Increases C. albicans Biofilm Formation and Results in Differential Expression of Pro- and Anti-Inflammatory Cytokines. Infect Immun. 2007 May 1; 75(5):2612–20. PMID: 17339351

Katragkou A, Kruhlak MJ, Simitsopoulou M, Chatzimoschou A, Taparkou A, Cotten CJ, et al. Interactions between Human Phagocytes and Candida albicans Biofilms Alone and in Combination with Antifungal Agents. J Infect Dis. 2010 Jun 15; 201(12):1941–9. doi: 10.1086/652783 PMID: 20415537

Chandra J, Kuhn DM, Mukherjee PK, Hoyer LL, McCormick T, Ghannoum MA. Biofilm formation by the fungal pathogen Candida albicans: development, architecture, and drug resistance. J Bacteriol. 2001 Sep; 183(18):5385–94. PMID: 11514524

Lamfon H. Susceptibility of Candida albicans biofilms grown in a constant depth film fermentor to chlorhexidine, fluconazole and miconazole: a longitudinal study. J Antimicrob Chemother. 2004 Jan 16; 53 (2):383–5. PMID: 14729749

Taff HT, Mitchell KF, Edward JA, Andes DR. Mechanisms of Candida biofilm drug resistance. Future Microbiol. 2013 Oct; 8(10):1325–37. doi: 10.2217/fmb.13.101 PMID: 24059922

Nett JE, Crawford K, Marchillo K, Andes DR. Role of Fks1p and Matrix Glucan in Candida albicans Biofilm Resistance to an Echinocandin, Pyrimidine, and Polyene. Antimicrob Agents Chemother. 2010 Aug 1; 54(8):3505–8. doi: 10.1128/AAC.00227-10 PMID: 20516280

Tobudic S, Kratzer C, Lassnigg A, Graninger W, Presterl E. In vitro activity of antifungal combinations against Candida albicans biofilms. J Antimicrob Chemother. 2010 Feb 1; 65(2):271–4. doi: 10.1093/jac/ dkp429 PMID: 19996142

Ramage G, Bachmann S, Patterson TF, Wickes BL, López-Ribot JL. Investigation of multidrug efflux pumps in relation to fluconazole resistance in Candida albicans biofilms. J Antimicrob Chemother. 2002Jun; 49(6):973–80. PMID: 12039889

Nett JE, Sanchez H, Cain MT, Andes DR. Genetic basis of Candida biofilm resistance due to drug sequestering matrix glucan. J Infect Dis. 2010 Jul; 202:171–175. doi: 10.1086/651200 PMID: 20497051

Mitchell KF, Zarnowski R, Sanchez H, Edward JA, Reinicke EL, Nett JE, et al. Community participation in biofilm matrix assembly and function. Proc Natl Acad Sci U S A. 2015 Mar 13;

Mukherjee PK, Chandra J, Kuhn DM, Ghannoum MA. Mechanism of fluconazole resistance in Candida albicans biofilms: phase-specific role of efflux pumps and membrane sterols. Infect Immun. 2003 Aug; 71(8):4333–40. PMID: 12874310

White TC, Marr KA, Bowden RA. Clinical, cellular, and molecular factors that contribute to antifungal drug resistance. Clin Microbiol Rev. 1998 Apr; 11(2):382–402. PMID: 9564569

Davies D. Understanding biofilm resistance to antibacterial agents. Nat Rev Drug Discov. 2003 Feb; 2 (2):114–22. PMID: 12563302

Liu S, Hou Y, Chen X, Gao Y, Li H, Sun S. Combination of fluconazole with non-antifungal agents: a promising approach to cope with resistant Candida albicans infections and insight into new antifungal agent discovery. Int J Antimicrob Agents. 2014 May; 43(5):395–402. doi: 10.1016/j.ijantimicag.2013. 12.009 PMID: 24503221

Odds FC. Synergy, antagonism, and what the chequerboard puts between them. J Antimicrob Chemother. 2003 Jun 12; 52(1):1–1. PMID: 12805255

Chavez-Dozal AA, Lown L, Jahng M, Walraven CJ, Lee SA. In vitro analysis of finasteride activity against Candida albicans urinary biofilm formation and filamentation. Antimicrob Agents Chemother. 2014 Oct; 58(10):5855–62. doi: 10.1128/AAC.03137-14 PMID: 25049253

Fiori A, Van Dijck P. Potent Synergistic Effect of Doxycycline with Fluconazole against Candida albicans Is Mediated by Interference with Iron Homeostasis. Antimicrob Agents Chemother. 2012 Jul 1; 56 (7):3785–96. doi: 10.1128/AAC.06017-11 PMID: 22564841

Pemmaraju SC, Pruthi PA, Prasad R, Pruthi V. Candida albicans biofilm inhibition by synergistic action of terpenes and fluconazole. Indian J Exp Biol. 2013 Nov; 51(11):1032–7. PMID: 24416942

Chandrasekar PH, Sobel JD. Micafungin: A New Echinocandin. Clin Infect Dis. 2006 Apr 15; 42 (8):1171–8. PMID: 16575738.

Bailey, E. M., D. J. Krakovsky, et al. (1990). "The triazole antifungal agents: a review of itraconazole and fluconazole." Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 10(2): 146-153.

Seethalakshmi, I.; Sathishkumar, J.; Muthu, S. and Saritha, V. (2010). Virulence and cytotoxicity of seafood borne Aeromonas hydrophila. Brazil. J. Microbiol., 41: 978-983. 26- 67.

Kuhun, D. M., T. George, et al. (2002). "Antifungal susceptibility of Candida biofilms: unique efficacy of amphotericin B lipid formulations and echinocandins." Antimicrobial Agents and Chemotherapy 46(6): 1773-1780. 27- 114.

Rippon, J. W. (1988). Medical Mycology. 3rd. W. B. Saunders Co. Philadelphia .U.S.A.

Hajjeh, R. A., A. N. Sofair, et al. (2004). "Incidence of bloodstream infections due to Candida species and in vitro susceptibilities of isolates collected from 1998 to 2000 in a population-based active surveillance program." Journal of Clinical Microbiology 42(4): 1519-1527.

29- Sun S, Li Y, Guo Q, Shi C, Yu J & Ma L (2008) In vitro interactions between tacrolimus and azoles against albicans determined by different methods. Antimicrob Agents Ch 52: 409–417.

Cateau E, Rodier M-H, Imbert C. In vitro efficacies of caspofungin or micafungin catheter lock solutions on Candida albicans biofilm growth. J Antimicrob Chemother. 2008 Apr 1; 62(1):153–5. doi: 10.1093/ jac/dkn160 PMID: 18407917

Uchida K, Nishiyama Y, Yokota N, Yamaguchi H. In vitro antifungal activity of a novel lipopeptide antifungal agent, FK463, against various fungal pathogens. J Antibiot (Tokyo). 2000 Oct; 53(10):1175–81

Mikamo H. In vitro antifungal activity of FK463, a new water-soluble echinocandin-like lipopeptide. J Antimicrob Chemother. 2000 Sep 1; 46(3):485–7. PMID: 10980180

Published

19-05-2022

How to Cite

Khudhair, I. H., & Daeikh, A. K. (2022). Study of the effect of ethanol alcohols on yeasts and fungi isolated from the nail. International Journal of Health Sciences, 6(S3), 6902–6910. https://doi.org/10.53730/ijhs.v6nS3.7590

Issue

Section

Peer Review Articles