Handling keloid and hypertrophic scars by long-pulsed Nd: YAG laser
Evaluating effectiveness
Keywords:
long pulsed Nd: YAG laser, keloid, hypertrophic scar, vancouver scar scaleAbstract
Background and objectives: Keloids and HTs appear to have an abundant healing response that sets a challenge for physicians. Patients and methods: Patients with keloids and HTs were handled by a long-pulsed 1064 nm Nd: YAG laser every 4 weeks for five sessions. The number of patients was twenty. The scars were rated by VSS, consisting of 4 ingredients: vascularity, pigmentation, pliability, and height. Moreover, histopathological assessment by hematoxylin and eosin stain and Masson trichrome stain. After 6 months of finishing the treatment, the lesion was estimated to evaluate the recurrence rate. Results: According to VSS, there was a considerable improvement in vascularity, pigmentation, pliability, and height after the treatment than before the treatment. The score of the scar assessment dropped off from 9.40 to 3.75 after treatment. Hematoxylin and eosin staining and Elastica Masson-Goldner staining appeared to change the structure of the tissue collagen. Collagen bundles lost their whirl structure, and the thickness of the collagen layer decreased. The Wall of blood vessels was thinner, and the number of blood vessels was decreased. Conclusion: The treatment of keloids and HTs showed great results with a long-pulsed Nd-YAG laser.
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References
Kant Bevan den Kerckhove E, Colla C, et al. A new treatment of hypertrophic and keloid scars with combined triamcinolone and verapamil: a retrospective study. Eur J Plast Surg. 2018;41: 69-80.
Lee DE, Ryan M, Ayoub NT. Metalloproteinases, and Vitamin D in Keloids and Hypertrophic Scars. PRS Global Open. 2015; 16:9-12.
Lee G, Hunter-Smith DJ, Rozen WM. Autologous fat grafting in keloids and hypertrophic scars: a review. Scars Burn Heal. 2017; 3:1-6.Penn JW, Grobbelaar AO, Rolfe KJ. The role of the TGF-β family in wound healing, burns and scarring: a review. Int J Burns Trauma. 2012; 2:18-28.
Espana A, Solano T, Quintanilla E. Bleomycin in the treatment of keloids and hypertrophic scars by multiple needle punctures. Dermatol Surg. 2001; 27: 23-27.
Guo Feng, Wang Xi-Qiao. The Review of Most Current Therapy for Large Area of Hypertrophic Scar and Keloid. Journal of Advanced Plastic Surgery Research.2015;1: 29-33.
Poetschke J, Gauglitz GG. Current options for the treatment of pathological scarring. JDDG. 2016; 3:6-13.
Akaishi S, Koike S, Dohi T, et al. Nd:YAG Laser Treatment of Keloids and Hypertrophic Scars. Eplasty. 2012; 12:5–17.
Ogawa R, Akaishi S , Izumi M. Histologic analysis of keloids and hypertrophic scars. Ann Plast Surg. 2009; 62:104–105.
Koike S, Akaishi S, Nagashima Y, et al. Nd:YAG Laser Treatment for Keloids and Hypertrophic Scars: An Analysis of 102 Cases. Plast Reconstr Surg Glob Open. 2014;2: 272-280.
Kumar K, Kapoor BS, Rai P, Shukla HS. In‑situ irradiation of keloid scars with Nd:YAG laser. J Wound Care. 2000; 9:213-215.
Abergel RP, Dwyer RM, Meeker CA, et al. Laser treatment of keloids: A clinical trial and an in vitro study with Nd:YAG laser. Lasers Surg Med. 1984; 4:291-295.
Dierickx C, Goldman MP, Fitzpatrick RE. Laser treatment of erythematous/hypertrophic and pigmented scars in 26 patients. Plast Reconstr Surg. 1995; 95:84-90.
Goldman MP, Fitzpatrick RE. Laser treatment of scars. Dermatol Surg. 1995; 21:685- 687.
Reiken SR, Wolfort SF, Berthiaume F, et al. Control of hypertrophic scar growth using selective photo thermolysis. Lasers Surg Med. 1997; 21:7‑12.
Bouzari N, Davis SC, Nouri K. Laser treatment of keloids and hypertrophic scars. Int J Dermatol. 2007; 46:80‑88.
Akaishi S, Koike S, Dohi T, et al. Nd:YAG Laser Treatment of Keloids and Hypertrophic Scars. Eplasty. 2012; 12:5-17.
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