Retrospective study for correlation of fetal middle cerebral artery PSV and fetal anemia using newborn hemoglobin and blood indices
Keywords:
Fetal MCA’S PSV, Multiple of Median (MoM), fetal hemoglobin, blood indicesAbstract
To establish relation between fetal MCA’s PSV in 3rd trimester and fetal anemia as non-invasive method. The study was done retrospectively, including 40 pregnant women who had raised PSV of MCA (Multiple of Median(MoM) >1.5) blood flow in third trimester and was correlated with the new born’s Hemoglobin and Blood indices (MCV and MCH). Forty fetuses who had MCA’s PSV more than 1.5 MoM(coming out to be around 66.50 ± 12.35 cm/seconds), after delivery, blood samples of these 40 neonate were taken, of which 37 were anemic based on hemoglobin and blood indices using reference range from study done by kumar et al8. Sensitivity was 92.5% and specificity around 88 %. Doppler spectral analysis of PSV of MCA is very reliable for predicting fetal anemia. MoM of PSV of Fetal MCA correlates very well with MoM of Neonatal Hemoglobin . Thus, fetal MCA’s PSV is very potential to replace invasive method for diagnosis of fetal anemia.
Downloads
References
D. Oepkes, R. Brand, F.P. Vandenbussche, R.H. Meerman, H.U.H. Kanhai. The use of ultrasonography and Doppler in the prediction of fetal haemolytic anaemia: a multivariate analysis, Br J Obstet Gynaecol, 101 (1994), pp. 680-684
Bowman JM. Haemolytic disease (Erythroblastsis fetalis). In: Creasy RK, Rensnik R, editors. Maternal-fetal medicine 4th. Philadelphia: W.B. Saunders; 1999. p. 736–67.
G. Mari, R.L. Deter, R.L. Carpenter. Noninvasive diagnosis by Doppler ultrasonography of fetal anemia due to maternal red-cell alloimmunization, N Eng J Med, 342 (2000), pp. 9-14
I.M.A. Teixeira, K. Duncan, E. Letsky, N.M. Fisk, Middle cerebral artery peak systolic velocity in the prediction of fetal anemia. Ultrasound Obstet Gynaecol, I5 (2000), pp. 305-308
D. Duker, D. Oepkes, G. Seaward, R. Windrim, G. Ryan, Noninvasive tests to predict fetal anemia: a study comparing Doppler and ultrasound parameter, Am J Obstet Gynaecol, 188 (2003), pp. 1310-1314
M. Segata, G. Mari, Fetal anemia: new technologies. Curr Opin Obstet Gynaecol, 16 (2004), pp. 153-158
M.H. Schenone, G. Mari, The MCA Doppler and its role in the evaluation of fetal anemia and fetal growth restriction, Clin Perinatol, 38 (1) (2011), pp. 83-102
Kishor Kumar R, Nandini Nagar and Prashanth Sarnadgouda, Anemia in new born review article, pediatric dimesnions.
Amy H Picklesimer, Kenneth J Moise, determinants of middle cerebral artery peak systolic velocity in human fetus, Pubmed.gov 2007
Published
How to Cite
Issue
Section
Copyright (c) 2022 International journal of health sciences
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Articles published in the International Journal of Health Sciences (IJHS) are available under Creative Commons Attribution Non-Commercial No Derivatives Licence (CC BY-NC-ND 4.0). Authors retain copyright in their work and grant IJHS right of first publication under CC BY-NC-ND 4.0. Users have the right to read, download, copy, distribute, print, search, or link to the full texts of articles in this journal, and to use them for any other lawful purpose.
Articles published in IJHS can be copied, communicated and shared in their published form for non-commercial purposes provided full attribution is given to the author and the journal. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
This copyright notice applies to articles published in IJHS volumes 4 onwards. Please read about the copyright notices for previous volumes under Journal History.