Vitamin D status in children with Cerebral palsy
A tertiary care center study
Keywords:
Vit. D, antiepileptic drug, Cerebral palsyAbstract
Background: Cerebral palsy(CP) is presently defined as a group of permanent disorders of the development of movement and posture, causing activity limitation, that are attributed to non-progressive disturbances that occurred in the developing fetal or infant brain. Low vitamin D levels in children with CP are also associated with decreased muscle strength, balance, muscle pain, paresthesias, and poor muscular coordination. Materials & Method: It is the Prospective observational cross-sectional study. The patients in the study group were of both sexes and aged 6 months to 12 years. All children apart from general tests underwent investigations for serum calcium total {By an automated analyzer}, serum phosphorus {By an automated analyzer}, serum alkaline phosphatase (SAP) levels {By an automated analyzer} and 25 OH vitamin D level {By CLIA (chemi luminescence immunoassay) method}. Results: Total 141 Children who satisfied inclusion and exclusion. Male children were 96 (68%) whereas female were 45(32%).The distribution by the CP type was Quadriplegia 44.0%, Diplegia 34.8%, Hemiplegia 7.1%, Monoplegia 1.4%, Hypotonic 2.1%, Dyskinetic 0.7%, Mixed 0.7%, Evolving CP 9.2%. Ambulatory CP children were 60 (42.5%) and non ambulatory were 81 (57.5%).
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