Study of some immunological markers associated with cytomegalovirus among spontaneous abortion women

https://doi.org/10.53730/ijhs.v6nS3.7897

Authors

  • Mohammed K. K. AL-Koufi Faculty of Science, University of Kufa, Iraq
  • Huda Jameel Baker AL-Khilkhali Faculty of Science, University of Kufa, Iraq

Keywords:

CMV, pregnant abortions, ELISA test

Abstract

The goal of this study was to investigate the existence of  CMV  in abortion women and also to observe if particular cytokines played a role in abortion induction. during the time between August   (2021)to January(2022).total of 60 women who have previous abortions, and the control group consisted of 25 healthy pregnant women with no signs of chronic inflammatory disease were gathered from Al Rifai hospital in Dhi Qar city. The patients range in age from 19 to 50 years. CMVwere examined on ELISA in blood samples taken from abortion women and healthy controls. A total of 60 samples were taken,60(100%) were positive results for CMV while the study of pregnant women revealed nil (zero per cent) negative results for every 25 samples using the ELISA   test. The distribution of aborted women according to their abortion frequency was revealed the first abortion was the highest percentage (34/60). and, most importantly,  CMV positive samples at a rate of one per cent 34(56.6%) demonstrates how important this virus is in the forecast the second and third abortions resulted in a total of 21 being aborted (35%) and 5(8.3%) respectively. 

Downloads

Download data is not yet available.

References

Al-Samarrae, E. A. A. (2010). Study the Relationship of Toxoplasma IgG Titer with Some Other Immunoglobulin and Complement Components. Iraqi J. Comm. Med, 23(2), 127-129.

A Naqid, I., H Yousif, S., & R Hussein, N. (2020). Seroprevalence of Rubella and Herpes Simplex Virus in Women with Miscarriage and Stillbirth in Zakho City, Kurdistan Region, Iraq: A Cross-Sectional Study. Women’s Health Bulletin, 7(1), 18-22.

Asaduzzaman, M., Mrida, A. H., Hasan, N., Faruq, M. O., Juliana, F. M., Islam, M. J., & Kabir, M. S. (2018). The effect of herpes simplex virus infection on different blood parameters: A transverse study. IOSR-JDMS, 17(9), 81-89.

Colugnati, F. A., Staras, S. A., Dollard, S. C., & Cannon, M. J. (2007). Incidence of cytomegalovirus infection among the general population and pregnant women in the United States. BMC infectious diseases, 7(1), 1-10.

Dreher, A. M., Arora, N., Fowler, K. B., Novak, Z., Britt, W. J., Boppana, S. B., & Ross, S. A. (2014). The spectrum of disease and outcome in children with symptomatic congenital cytomegalovirus infection. The Journal of pediatrics, 164(4), 855-859.

Drescher, B., & Bai, F. (2013). Neutrophil in viral infections, friend or foe?. Virus research, 171(1), 1-7. Enders, G., Daiminger, A., Bäder, U., Exler, S., & Enders, M. (2011). Intrauterine transmission and clinical outcome of 248 pregnancies with primary cytomegalovirus infection about gestational age. Journal of Clinical Virology, 52(3), 244-246.

Feldman, B., Yinon, Y., Oikawa, M. T., Yoeli, R., Schiff, E., & Lipitz, S. (2011). Pregestational, periconceptional, and gestational primary maternal cytomegalovirus infection: prenatal diagnosis in 508 pregnancies. American journal of obstetrics and gynaecology, 205(4), 342-e1. Grimes, D. A., & Stuart, G. (2010). Abortion jabberwocky: the need for better terminology. Contraception, 81(2),93-96.

Hussan, B. M. (2013). Study the prevalence of ACL, APL, CMV, HSV, Rubella and Toxoplasma gondii in aborted women in Baghdad. Medical Journal of Babylon, 10(2), 455-464.

Holers, V. M., Girardi, G., Mo, L., Guthridge, J. M., Molina, H., Pierangeli, S. S., ... & Salmon, J. E. (2002). Complement C3 activation is required for antiphospholipid antibody-induced fetal loss. The Journal of experimental medicine, 195(2), 211-220.

Kolte, A. M., Bernardi, L. A., Christiansen, O. B., Quenby, S., Farquharson, R. G., Goddijn, M., & Stephenson, M. D. (2015). Terminology for pregnancy loss prior to viability: a consensus statement from the ESHRE early pregnancy special interest group. Human reproduction, 30(3), 495-498.

Munro, S. C., Trincado, D., Hall, B., & Rawlinson, W. D. (2005). Symptomatic infant characteristics of congenital cytomegalovirus disease in Australia. Journal of paediatrics and child health, 41(8), 449-452 Naing, Z. W., Scott, G. M., Shand, A., Hamilton, S. T., van Zuylen, W. J., Basha, J., ... & Rawlinson, W. D. (2016). Congenital cytomegalovirus infection in pregnancy: a review of prevalence, clinical features, diagnosis and prevention. Australian and New Zealand Journal of Obstetrics and Gynaecology, 56(1),9-18.

Picone, O., Vauloup‐Fellous, C., Cordier, A. G., Guitton, S., Senat, M. V., Fuchs, F., ... & Benachi, A. (2013). A series of 238 cytomegalovirus primary infections during pregnancy: description and outcome. Prenatal diagnosis, 33(8), 751-758.

Rezaei, A., & Dabbagh, A. (2002). T-helper (1) cytokines increase during early pregnancy in women with a history of recurrent spontaneous abortion. Medical Science Monitor, 8(8), CR607-CR610.

Saleh, D. S., & Kharibet, K. E. (2015). Detection of Cytomegalovirus, Rubella virus, and IL-2 Levels in a Sample of Recurrently Aborted Iraqi Women. Iraqi Journal of Science, 56(3A), 1890-1894.

Yenicesu, İ., Yetgin, S., Özyürek, E., & Aslan, D. (2002). Virus-associated immune thrombocytopenic purpura in childhood. Pediatric haematology and oncology, 19(6), 433-437.

Yezlankyzy, T., &Niazbekov, S. (2015). Abortion Is the Same as a Murder of an Innocent Human Being. International Student’s Journal of Medicine, 1(4).

Published

25-05-2022

How to Cite

AL-Koufi, M. K. K., & AL-Khilkhali, H. J. B. (2022). Study of some immunological markers associated with cytomegalovirus among spontaneous abortion women. International Journal of Health Sciences, 6(S3), 8296–8309. https://doi.org/10.53730/ijhs.v6nS3.7897

Issue

Section

Peer Review Articles

Most read articles by the same author(s)