Effect of the COVID-19 vaccine on sex hormones and their relationship with IL-10
Keywords:
COVID-19 Vaccine, Sex Hormone, IL-10Abstract
The current study included 80 people who were vaccinated with the COVID-19 vaccine, 40 males and 40 females, samples were drawn after the first and second doses, and 40 (20 males and 20 females) people as a control group in Thi-Qar province, southern Iraq, and for the period from November 2021 to January 2022, sex hormones were estimated for male and female and IL-10. Sex hormones were estimated by an automated CL device instrument, while IL-10 was measured by third-generation ELISA. The current study showed a significant decrease in FSH and testosterone levels after the second dose in the male group, while females showed a significant decrease in LH after the second dose, and IL-10 was decreased after the second dose in the male group. The LH, E2, and testosterone were significantly increased in both the first and second dose when compared with the control group, while non-significant in the level of FSH. In conclusion, the sex hormone effect of the COVID-19 vaccine and the vaccine induce hormone secretion in vaccinated people compared with non-vaccinated people, while FSH is not affected by the COVID-19 vaccine.
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