Management of asthma (ḌĪQ Al-Nafas) in Unani system of medicine
Keywords:
Asthma, Ḍīq al-Nafas, Dama, Herbal drugs, UnaniAbstract
Numerous functions within the human body have been conducted throughout time without anyone being aware of them or interfering with their functioning. One of them is breathing. Thus, when a person develops trouble breathing and must exert considerable effort to inhale and exhale, it becomes an argument for a will condition. Asthma is a chronic inflammatory airway disorder that is often characterized by reversible airflow obstruction and chest tightness, wheezing, coughing, and dyspnea, all of which are signs of airway obstruction. They can occur spontaneously, most frequently at night or early in the morning, the following activity or responding to an allergy. This potentially severe chronic disease places a significant financial burden on individuals and their families. The development of bronchodilators and corticosteroids simplified the management of bronchial asthma in modern medicine. In modern medicine, bronchial asthma is treated through bronchodilators and corticosteroids. Apart from this invention, comprehensive treatment of asthma is still a long way off. The Unani medical system takes a holistic approach to prevent and treating Asthma (Ḍīq al-Nafas). This article aims to describe Asthma (Ḍīq al-Nafas) and find a comprehensive and safe method of managing asthma through a holistic approach to the Unani system of medicine.
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Afshar AA, Ghafarzade S, Yavari B, Athari SS. Survey the effect of Herbal Medicine on pathogenesis of Eosinophilic Chemotactic Factors in experimental Allergic Asthma. Adv Biores. 2014;5(1):160-4.
Aggarwal AN, Chaudhry K, Chhabra SK, D Souza GA, Gupta D, Jindal SK, Katiyar SK, Kumar R, Shah B, Vijayan VK. Prevalence and risk factors for bronchial asthma in Indian adults: a multicenter study. Indian Journal of Chest Diseases and Allied Sciences. 2006 Jan 18;48(1):13.
Agrawal B, Mehta A. Anti-asthmatic activity of Moringa oleifera Lam: A clinical study. Indian Journal of pharmacology. 2008 Jan;40(1):28.
Al Bayaty MA. Mechanism of the tracheal smooth muscle relaxant activity of the Cordia myxa plant extract in sheep. The Iraqi Journal of Veterinary Medicine. 2008 Dec 31;32 (2):214-26.
Al Qamari HAM. Ghina Muna, Central Council for Research in Unani Medicine, New Delhi. 138-139.
Ali B, Mujeeb M, Aeri V, Mir SR, Faiyazuddin M, Shakeel F. Anti-inflammatory and antioxidant activity of Ficus carica Linn. leaves. Natural product research. 2012 Mar 1;26(5):460-5.
Amiri H, Essential Oils Composition and Antioxidant Properties of Three Thymus Species, Evidence-Based Complementary and Alternative Medicine, vol. 2012, https://doi.org/10.1155/2012/728065
Anonymous, WHO. Asthma, World Health Organization. available at: https://www.who.int/news-room/fact-sheets/detial/asthma (accessed on 10th June 2021a).
Anonymous. Concept of temperament (Mizāj) and its assessment in Unani System of Medicine (2020). Published by National Health Portal. Available at: https://www.nhp.gov.in (accessed on 3rd April 2021).
Anonymous. Global Initiative for Asthma. A Pocket Guide for Health Professionals, 2017, GINA Science Committee, pp.6. Available at: https://ginasthma.org accessed on 10th May 2017.
Anonymous. Global Initiative for Asthma. A Pocket Guide for Health Professionals, 2021b. GINA Science Committee, pp.9. Available at: https://ginasthma.org accessed on 10th May 2021b.
Anonymous. National Formulary of Unani Medicine, Part-I. New Delhi, India: CCRUM, Department of AYUSH, Ministry of Health & Family Welfare, Government of India, 2006.
Anonymous. National Formulary of Unani Medicine, Part-III, First edition. New Delhi, India: Department of AYUSH, Ministry of Health & Family Welfare, Government of India), 2001.
Anonymous. National Formulary of Unani Medicine, Part-V, New Delhi, India: Department of AYUSH, Ministry of Health & Family Welfare, Government of India, 2008.
Arantes S, Candeias F, Lopes O, Lima M, Pereira M, Tinoco T, Cruz-Morais MJ. Martins R. Pharmacological and Toxicological Studies of Essential Oil of Lavandula stoechas subsp. Luisieri. Planta Med 2016; 82(14): 1266-1273
Arora P, Ansari SH, Najmi AK, Anjum V, Ahmad S. Investigation of anti-asthmatic potential of dried fruits of Vitis vinifera L. in animal model of bronchial asthma. Allergy, Asthma & Clinical Immunology. 2016 Dec;12(1):1-2.
Arzani, A. Tibb-i-Akbar. Adab Printing Press, Lahore. 1988, p. 313-319.
Asadi-Samani M, Bahmani M, Rafieian-Kopaei M. The chemical composition, botanical characteristic and biological activities of Borago officinalis: a review. Asian Pacific journal of tropical medicine. 2014 Sep 1;7: S22-8.
Athiya V, Gupta S, Chourasiya A. Phytochemical Screening and Assessment of Adhatoda Vasica (Leaf) For Antihistaminic Activity. Journal of Drug Delivery and Therapeutics. 2019 Dec 19;9(4-s):1092-5.
Bashir S, Abbas S, Gilani AH, Khan A. Studies on bronchodilator and cardiac stimulant activities of Urginea indica. Bangladesh Journal of Pharmacology, 2013 May 20;8(3):249-54.
Benso B, Franchin M, Massarioli AP, Paschoal JA, Alencar SM, Franco GC, Rosalen PL. Anti-inflammatory, anti-osteoclastogenic and antioxidant effects of Malva sylvestris extract and fractions: in vitro and in vivo studies. PLoS One. 2016 Sep 19;11(9): e0162728.
Boskabady MH, Ramazani-Assari M. Relaxant effect of Pimpinella anisum on isolated guinea pig tracheal chains and its possible mechanism (s). Journal of Ethnopharmacology. 2001 Jan 1;74(1):83-8.
Buist AS. Similarities and differences between asthma and chronic obstructive pulmonary disease: treatment and early outcomes. European Respiratory Journal. 2003 Jan 1;21(39 suppl):30s-5s.
Cannizzaro T. History of asthma (part one) In the beginning., pp. 1-2. Available at: https://asthma.net/living/history-of-asthma-part-one-in-begining 2017. accessed on 15th April 2021.
Choi MS, Do KM, Park YB, Jeon SM, Jeong TS, Lee YK, Lee MK, Bok SH. Effect of naringin supplementation on cholesterol metabolism and antioxidant status in rats fed high cholesterol with different levels of vitamin E. Annals of Nutrition and Metabolism. 2001;45(5):193-201.
Conforti F, Sosa S, Marrelli M, Menichini F, Statti GA, Uzunov D, Tubaro A, Menichini F, Della Loggia R. In vivo anti-inflammatory and in vitro antioxidant activities of Mediterranean dietary plants. Journal of Ethnopharmacology. 2008 Feb 28;116(1):144-51.
Doshi VB, Shetye VM, Mahashur AA, Kamat SR. Picrorrhiza kurroa in bronchial asthma. Journal of postgraduate medicine. 1983 Apr 1;29(2):89.
Geetha T, Varalakshmi P. Anti-inflammatory activity of lupeol and lupeol linoleate in rats. Journal of ethnopharmacology. 2001 Jun 1;76(1):77-80.
Ghani N. Khazainul Advia.: Idara Kitabul Shifa, New Delhi, India. 2011.
Ghayur MN, Gilani AH, Janssen LJ. Ginger attenuates acetylcholine-induced contraction and Ca2+ signaling in murine airway smooth muscle cells. Canadian journal of physiology and pharmacology. 2008 May;86(5):264-71.
Ghayur MN, Gilani AH. Inhibitory activity of ginger rhizome on airway and uterine smooth muscle preparations. European Food Research and Technology. 2007 Feb;224(4):477-81.
Gholamnejad Z, Byrami G, Boskabady MH, Iranshahi M. Possible mechanism (s) of the relaxant effect of asafoetida (Ferula assa-foetida) oleo-gum-resin extract on guinea-pig tracheal smooth muscle. 2012: 10-16
Green AY, Green D. Wy 23205, a new non-steroidal anti-inflammatory agent. British journal of pharmacology. 1971 Aug;42(4):638P.
Hong JW, Yang GE, Kim YB, Eom SH, Lew JH, Kang H. Anti-inflammatory activity of cinnamon water extract in vivo and in vitro LPS-induced models. BMC Complementary and Alternative Medicine. 2012 Dec;12(1):1-8.
Huber R, Stintzing FC, Briemle D, Beckmann C, Meyer U, Gründemann C. In vitro antiallergic effects of aqueous fermented preparations from Citrus and Cydonia fruits. Planta Medica. 2012 Mar;78(04):334-40.
Hussain N, Kakoti BB, Rudrapal M, Sarwa KK. Anti-inflammatory and Antioxidant Activities of Cordia dichotoma Forst. Biomed. Pharmacol. J. 2020 Dec 1; 13:2093-9.
Ibn Hubul MAAAA. Kitab-ul-Mukhtarat Fi'l-Tib, (Urdu), Central Council for Research in Unani Medicine, New Delhi. 2004;(III): 161.
Ibn Sina, Al-Qanun fī’l Tibb, vol III, Idara Kitabul Shifa, New Delhi. 2010, 709
Janbaz KH, Shabbir A, Mehmood MH, Gilani AH. Insight into mechanism underlying the medicinal use of Cydonia oblonga in gut and airways disorders. J Anim Plant Sci. 2013 Jan 1;23:330-6.
Kabir HM. Al-Akseer, (Urdu), Aijaz Publication House, New Delhi, 2003;(I): 436-437.
Kabir HM. Makhzan-ul Mufradat Al Maaroof Khawas-ul Advia, Faisal Publishers, Deoband, 2000.
Kabir HM. Tarjuma Kabir, Part-2, Delhi. 1960; (II). Matba Daftarul Maseeh: 557-558.
Kaithwas G, Mukherjee A, Chaurasia AK, Majumdar DK. Anti-inflammatory, analgesic, and antipyretic activities of Linum usitatissimum L.(flaxseed/linseed) fixed oil. 2011.
Karaman M, Firinci F, Cilaker S, Uysal P, Tugyan K, Yilmaz O, Uzuner N, Karaman O. Anti-inflammatory effects of curcumin in a murine model of chronic asthma. Allergologia et Immunopathologia. 2012 Jul 1;40(4):210-4.
Karnick CR. Pharmacology of Ayurvedic medicinal plants. Shri Sat Guru Publications. 1996. 51-57.
Khan AU, Gilani AH. Natural Products Useful in Respiratory Disorders: Focus on Side‐Effect Neutralizing Combinations. Phytotherapy Research. 2015 Sep;29(9):1265-85.
Khan HA, Haziq (Urdu). Madina Publication Company, Karach, 1987, p.203-206.
Khan HMA, Muhit-i-Azam. Central Council for Research in Unani Medicine, New Delhi. (2012); (I, II, III).
Khan IA, Aziz A, Munawar SH, Manzoor Z, Afzal A. Evaluation of Counter Irritant Potential of Aqueos Bark Extract of CinnmonLoureiroi. Int J Pharm Res Allied Sci. 2014; 3:30-5.
Khare CP. Indian Medicinal Plants: an illustrated dictionary. Springer Science & Business Media; 2008 Apr 22.
Kirmani NBE. Sharah Al-Asbab-wa-Alamat (Urdu), Central Council for Research in Unani Medicine, New Delhi. 2010, (II): 437-438
Kloss J. The Handbook of Herbal Medicine. Sri Satguru Publication. 2001. 195-201.
Kumar V, Abbas AK, Fausto N, Aster JC. Robbins and Cotran pathologic basis of disease, professional edition e-book. Elsevier Health Sciences; 2014 Aug 27.
Lee BK, Park SJ, Nam SY, Kang S, Hwang J, Lee SJ, Im DS. Antiallergic effects of sesquiterpene lactones from Saussurea costus (Falc.) Lipsch. determined using in vivo and in vitro experiments. Journal of ethnopharmacology. 2018 Mar 1; 213:256-61.
Lee YM, Kim DK, Kim SH, Shin TY, Kim HM. Antianaphylactic activity of Poncirus trifoliata fruit extract. Journal of ethnopharmacology. 1996 Nov 1;54(2-3):77-84.
Linden A, Bergendal A, Ullman A, Skoogh BE, Lofdahl CG. Salmeterol, formoterol, and salbutamol in the isolated guinea pig trachea: differences in maximum relaxant effect and potency but not in functional antagonism. Thorax. 1993 May 1;48(5):547-53.
Liu Y, Kakani R, Nair MG. Compounds in functional food fenugreek spice exhibit anti-inflammatory and antioxidant activities. Food Chemistry. 2012 Apr 15;131(4):1187-92.
Lone AH, Ahmad T, Anwar M, Sofi G, Imam H, Habib S. Perception of health promotion in Unani herbal medicine. Journal of Herbal Medicine. 2012 Apr 1;2(1):1-5.
Ma C, Ma Z, Fu Q, Ma S. Curcumin attenuates allergic airway inflammation by regulation of CD4+ CD25+ regulatory T cells (Tregs)/Th17 balance in ovalbumin-sensitized mice. Fitoterapia. 2013 Jun 1; 87:57-64.
Ma X, Ma X, Ma Z, Sun Z, Yu W, Wang J, Li F, Ding J. The Effects of Uygur Herb Hyssopus officinalis L. on the Process of Airway Remodeling in Asthmatic Mice", Evidence-Based Complementary and Alternative Medicine, vol. 2014, https://doi.org/10.1155/2014/710870.
Madeline R. Vann, MPH. Foods that help relieve asthma symptoms. 2021. Available at: https://www.everydayhealth.com accessed on 20th May.
Mahato D, Sahu AP, Sharma HP. Phytochemical and antioxidant evaluation of Urginea indica Kunth. Indian Journal of Traditional Knowledge, 2018, 17(4):783-788.
Makino T, Shiraki Y, Mizukami H. Interaction of gypsum and the rhizome of Anemarrhenaasphodeloides plays an important role in antiallergic effects of byakkokakeishito in mice. Journal of natural medicines. 2014 Jul;68(3):505-12.
Mallikarjuna GU, Dhanalakshmi S, Raisuddin S, Rao AR. Chemomodulatory influence of Ferula asafoetida on mammary epithelial differentiation, hepatic drug-metabolizing enzymes, antioxidant profiles, and N-methyl-N-nitrosourea-induced mammary carcinogenesis in rats. Breast cancer research and treatment. 2003 Sep;81(1):1-0.
McDermott, A. Diet Recommended for People with Asthma. 2019. Available at: https://www.healthline.com accessed on 10th April.
Miraj S, Kiani S. Study of antibacterial, antimycobacterial, antifungal, and antioxidant activities of Foeniculum vulgare: A review. Der Pharmacia Lettre. 2016;8(9):200-5.
Mohan H. Textbook of Pathology, 8th edition, Jaypee Brothers Medical Publishers, New Delhi. 2019: 484-485, 505-507.
Naik SR, Bhagat S, Shah PD, Tare AA, Ingawale D, Wadekar RR. Evaluation of antiallergic and anti-anaphylactic activity of ethanolic extract of Zizyphus jujuba fruits in rodents. RevistaBrasileira de Farmacognosia. 2013 Sep 1;23(5):811-8.
Neveu WA, Allard JL, Raymond DM, Bourassa LM, Burns SM, Bunn JY, Irvin CG, Kaminsky DA, Rincon M. Elevation of IL-6 in the allergic asthmatic airway is independent of inflammation but associates with loss of central airway function. Respiratory research. 2010 Dec;11(1):1-0.
Ni Z, Zhang Q, Qian J, Wang L. Effect of Astragalin on matrix secretion and beta 1 integrin mRNA expression in human mesangial cells. Chinese medical journal. 1999 Dec 1;112(12):1063-7.
Ninave PB, Patil SD. Anti-asthmatic potential of Zizyphus jujuba Mill and Jujuboside B.–Possible role in the treatment of asthma. Respiratory physiology & neurobiology. 2019 Feb 1; 260:28-36.
Nosal'ova G, Strapkova A, Kardosova A, Capek P, Zathurecký L, Bukovská E. Antitussive action of extracts and polysaccharides of marshmallow (Althea officinalis L., var. robusta). Die Pharmazie. 1992 Mar 1;47(3):224-6.
Nuhu H, Ghani A. Alkaloid content of the leaves of three Nigerian Datura species. Nigerian Journal of Natural Products and Medicine. 2002;6(1):15-8.
Paliwa JK, Dwivedi AK, Singh S, Gutpa RC. Pharmacokinetics and in-situ absorption studies of a new antiallergic compound 73/602 in rats. International journal of pharmaceutics. 2000 Mar 20;197(1-2):213-20.
Pel P, Kim YM, Chin YW. Chemical Constituents with Antiallergic Activity from the Barks of Cinnamomum cambodianum Collected in Cambodia. Bulletin of the Korean Chemical Society. 2015 Jan;36(1):384-7.
Rajanandh MG, Nageswari AD, Irshad PP, Ramasamy C. Does dose reduction of an inhaled corticosteroid with the addition of leukotriene antagonist is clinical significance in asthma patients. An aandomized clinical trial. World Appl Sci J. 2013; 24:276-81.
Ramya A, Geetha P, Nandhini M, Raja M. The Role of Leukotriene Receptor Antagonist as an add on therapy to β2-Agonists in Acute Asthma. Research Journal of Pharmacy and Technology. 2019;12(4):1974-8.
Rao YK, Geethangili M, Fang SH, Tzeng YM. Antioxidant and cytotoxic activities of naturally occurring phenolic and related compounds: a comparative study. Food and Chemical Toxicology. 2007 Sep 1;45(9):1770-6.
Razi Z. Kitab Al Hawi, Part-4, Hyderabad: Matba DairatulMuarif, 1957 b; 1-2.
Razi Z. Kitab-al Fakhir. Central Council for Research in Unani Medicine, New Delhi. 2007; vol I, part II. 175-176.
Razi Z. Kitab-al Hawi. Central Council for Research in Unani Medicine, New Delhi. 1998; IV .9-10.
Rout OP, Acharya R, Mishra SK. In-Vitro Antioxidant potentials in leaves of Coleus aromaticus Benth and rhizomes of Zingiber zerumbet (L.) SM. Journal of Applied Pharmaceutical Science. 2011 Oct 1;1(8):194.
Saleh S, El Denshary E, Mahran N. Nigella sativa (Black seed) oil: anti-inflammatory and antioxidant effects in experimental models of allergic asthma. InFirst USIM International Conference on Medicine and Health (ICMH2012), Kuala Lumpur. http://dx. doi. org/10.13140/2.1 2012 May (Vol. 3966).
Saran N, Anandharaj B, Bupesh G, Vasanth S, Surendhar PA. In vitro antioxidant potential of Justicia adhatoda leaf extracts against 1, 1-diphenyl picryl hydrazyl, hydroxyl, and nitrous oxide free radicals. Drug Invention Today. 2019 Aug 15;12(8):1736-40.
Shah SA, Akhtar N, Akram M, Shah PA, Saeed T, Ahmed K, Asif HM. Pharmacological activity of Althaea officinalis L. Journal of Medicinal Plants Research. 2011 Oct 30;5(24):5662-6.
Singh S, Agrawal SS. Anti-asthmatic and anti-inflammatory activity of Ocimum sanctum. International Journal of pharmacognosy. 1991 Jan 1;29(4):306-10.
Singh SK, Patel JR, Dubey PK, Thakur S. A review on anti-asthmatic activity of traditional medicinal plants. International journal of pharmaceutical sciences and research. 2014 Oct 1;5(10):4097.
Sockrider M, Fussner L. What is asthma? American Journal of Respiratory and Critical Care Medicine. 2020 Nov 1;202(9):P25-6.
Sullivan D, Felman A. "A Brief History of Asthma: Development, understanding, and treatments". (2018). Available at: https://www.medicalnewstoday.com (accessed on 16 April 2021 at 12PM).
Sunkara Y, Robinson A, Babu KS, Naidu VG, Vishnuvardhan MV, Ramakrishna S, Madhavendra SS, Rao JM. Anti-inflammatory and cytotoxic activity of chloroform extract of roots of Saussurea lappa Clarke. Journal of Pharmacy Research. 2010;3(8):1775-8.
Tabari RAHAS, Firdaws al-Hikma fi’l Tibb, (Urdu) Central Council for Research in Unani Medicine, New Delhi. 2010. 428-430.
Tewtrakul S, Subhadhirasakul S. Anti-allergic activity of some selected plants in the Zingiberaceae family. Journal of ethnopharmacology. 2007 Feb 12;109(3):535-8.
Vinaya M, Kamdod MA, Swamy M, Swamy M. Bronchodilator activity of Ocimum sanctum Linn. (Tulsi) in mild and moderate asthmatic patients in comparison with salbutamol: a single-blind cross-over study. Int J Basic Clin Pharmacol. 2017 Mar;6(3):511.
WC Evans. Trease and Evans Pharmacognosy, 15th Edn, WB Saunders Company Ltd., London, 2003; 299, 471, 485.
Wise, T.N., Church F and Va, 1985. Psychiatric Aspects of Chronic Pulmonary Diseases (Advances in Psychosomatic Medicine). 14th edition, S. Kargel Basel, pp.1, 5. Available at: https://ccrum.res.in (accessed on 25th April 2021 at 10AM)
Wu X, Xiao F, Zhang Z, Li X, Xu Z. Research on the analgesic effect and mechanism of bornyl acetate in volatile oil from Amomum villosum. Zhong yaocaiZhongyaocai Journal of Chinese medicinal materials. 2005 Jun 1;28(6):505-7.
Yang XM, Yu W, Ou ZP, Ma HL, Liu WM, Ji XL. Antioxidant and immunity activity of water extract and crude polysaccharide from Ficus carica L. fruit. Plant Foods for Human Nutrition. 2009 Jun;64(2):167-73.
Zanwar AA, Hegde MV, Bodhankar SL. In vitro antioxidant activity of ethanolic extract of Linum usitatissimum. Pharmacology online. 2010; 1:683-96.
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