Medical microbiology
Detection of biofilm production in candida species from blood stream patients
Keywords:
biofilm production, candida species, blood stream patientsAbstract
Candida species are the fourth most common cause of bloodstream infections and are the leading cause of invasive fungal infections among hospitalized patients [1]. Candidemia is a life-threatening fungal infection associated with a mortality rate of 38%; [2].The spectrum of candidemia has changed with the emergence of non- albicans Candida (NCAC) species, a strain with the threat of increased mortality especially in immunocompromised and severely ill patients [4]. It is very important to identify Candida to the species level to optimize the selection of the antifungal agent. More importantly, intrinsic and emerging resistance represents a major challenge for empirical, therapeutic and prophylactic strategies. Candida species have also been isolated from the respiratory tract, mouth, skin, ear and eye. Candida is a true opportunistic pathogen that under certain circumstances is able to invade tissues normally resistant to infection.
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