A clinico-histopathological study of ectopic pregnancy in a tertiary care hospital with special focus on histomorphology of fallopian tubes in tubal ectopic pregnancy

Saket Sharma; Manisha M. Shah; Isha M. Shah; Manish R. Shah

doi:10.53730/ijhs.v6nS3.8438

Authors

Saket Sharma M.B.B.S., M.D. (Pathology); Senior Resident, Department of Pathology, Medical College Baroda, Gujarat, India
Manisha M. Shah M.B.B.S., M.D. (Pathology); Assistant Professor, Department of Pathology, Medical College Baroda, Gujarat, India
Isha M. Shah 2nd year MBBS student, GMERS Medical College, Gotri, Vadodara-390021, Gujarat, India
Manish R. Shah
manishshah2001in@yahoo.co.in
M.S. (Orthopaedics), Associate Professor, Dept. of Orthopaedics, Dhiraj Hospital, Smt. BK Shah Medical Institute & Research Centre, Sumandeep Vidyapeeth Deemed to be University, Piparia, Vadodara 391760 Gujarat India

Keywords:

ectopic pregnancy, tubal ectopic pregnancy, chronic salpingitis, salpingitis isthmica nodosa

Abstract

Introduction: Ectopic pregnancy can present as an acute life‑threatening emergency when it ruptures and accounts for about 10% of all maternal mortalities; therefore, it is imperative to diagnose the unruptured ectopic pregnancy such that timely intervention will prevent morbidity and mortality. The fallopian tube is the most common site for ectopic pregnancy (90-95%). With an increasing incidence of ectopic pregnancy worldwide, a histopathological study of the resected fallopian tubes becomes important to look for predisposing/associated findings such as acute salpingitis, chronic salpingitis and salpingitis isthmica nodosa (SIN). Objectives: The aim was to study the clinical presentation of ectopic pregnancy and its association with various factors like age and gravida status. It also aims to study the histomorphology of the fallopian tubes with ectopic gestation and note the presence of predisposing factors such as acute salpingitis, chronic salpingitis and SIN. Materials and Methods: A total of 79 specimens of ectopic pregnancy received in Department of Pathology for a retrospective period of 2.5-years from January 2019 to May 2021 were reviewed.

Downloads

Download data is not yet available.

References

Ravindra, Prasad S, Suguna BV. Histomorphology of fallopian tubes in ectopic pregnancy. Archives of Medicine and Health Sciences. 2016;4(2):201. doi:10.4103/2321-4848.196190

Sudha V, Thangaraj D. A retrospective study on ectopic pregnancy: a two year study. International Journal of Reproduction, Contraception, Obstetrics and Gynecology. 2016;5(12):4365-4368. doi:10.18203/2320-1770.ijrcog20164344

Kutluay L, Vicdan K, Turan C, Batioǧlu S, Oǧuz S, Gökmen O. Tubal histopathology in ectopic pregnancies. European Journal of Obstetrics and Gynecology and Reproductive Biology. 1994;57(2):91-94. doi:10.1016/0028-2243(94)90049-4.

Karaer A, Avsar FA, Batioglu S. Risk Factors for ectopic pregnancy a case- control study. Aust NZ Obstet Gynaecol. 2006:46:521-7.

Ory SJ, Villaneva AL, Sand PK. Conservative treatment of ectopic pregnancy with methotrexate. AM J, obstet, Gynecol. 1986;154:1299-306.

Jophy R, Thomas A, Mhaskar A. Ectopic pregnancy 5 years’ experience. J Obstet Gynecol India. 2002;52(4):55-8.

Shagufta SM, Samina M, REyaz AR, Wasiqa K. Ectopic pregnancy; an anlysis of 114 cases. JK- practitioner. 2012;17(4):20-3.

Panchal D, Vasihanav G, Solanki K. Study of Management inpatient with Ectopic pregnancy. National journal of Integrated Research in Medicine. 2011;2(3):91-4.

Gaddagi RA, Chandrashekbar AP. A Clinical Study of Ectopic pregnancy. Journal of clinical and Diagnostis Research. 2012;6:867-9.

Shetty S, Shetty A. A clinical study of Ecoptic pregnancies in a Tertiary care hospital of Mangalore,India. Innovative Journal of Medical and Health Science. 2014;4(1):305-9.

Levin AA, Schoenbaum SC, Stubblefield PG, Zimicki S, Monson RR. Ectopic pregnancy and prior induced abortion. Am J Public health. 1982 Mar;72(3):253-6.

Pendse V. Ectopic pregnancy: a review of 110 cases. J Obstet Gynecol Ind. 1981;31:100-5.

Udigwe GO, Umeonoihu OS, Mbachu II. Ectopic pregnancy: A 5 year review of cases at Nnamdikazikiwe University Teaching Hospital (NAUPTH) ZNEWI, NMJ. 2010:51:160-3.

Breen JL. A 21 year survey of 654 ectopic pregnancies. Am J Obstet Gynecol 1970;106:1004‑19.

Swenda TZ, Jogo AA. Ruptured tubal pregnancy in Makurid, North Central Nigaria. Niger J Med. 2008;17(1):75-7.

Green LK, Kott ML. Histopathologic findings in ectopic tubal pregnancy. Int J Gynecol Pathol 1989;8:255‑62.

Dubuisson JB, Aubriot FX, Cardone V, Vacher-Lavenu MC. Tubal causes of ectopic pregnancy. Fertil Steril 1986; 46: 970-972.

Banerjee A, Prateek S, Malik S, Dhingra D. Genital tuberculosis in adolescent girls from low socioeconomic status with acute ectopic pregnancy presenting at a tertiary care hospital in urban Northern India: Are we missing an opportunity to treat? Arch Gynecol Obstet 2012;286:1477‑82.

Saraçoglu FO, Mungan T, Tanzer F. Salpingitis isthmica nodosa in infertility and ectopic pregnancy. Gynecol Obstet Invest 1992;34:202‑5.

Skibsted L, Sperling L, Hansen U, Hertz J. Salpingitis isthmica nodosa in female infertility and tubal diseases. Hum Reprod 1991;6:828‑31.

Nyandra, M., Suryasa, W. (2018). Holistic approach to help sexual dysfunction. Eurasian Journal of Analytical Chemistry, 13(3), pp. 207–212.

Rinartha, K., & Suryasa, W. (2017). Comparative study for better result on query suggestion of article searching with MySQL pattern matching and Jaccard similarity. In 2017 5th International Conference on Cyber and IT Service Management (CITSM) (pp. 1-4). IEEE.