A study of hepatic function in multiple transfused thalassaemia patients
Keywords:
Thalassemia, ineffective erythropoiesis, splenomegalyAbstract
Background: Thalassemia syndomes are the most common genetic disorder on world wide basis . The selective pressures that have made the thalassemias so common are known but are assumed to relate to the geographic distrubution of malaria. Material & Methods: This was Prospective study conducted in the department of pediatrics in a teriary care hospital. The patients who had received m ore than 50 blood transfusions are considerd as multiple transfusion. Result: A total of 50 patients were enrolled in the study 90 % of patients were under 15 years of age male, female ratio was 1.27:1. The prevelance of thalassemia syndrome was common in sindhis and punjabis pupulation. Conculsion: The blood should be always screened for viral maricers, HIV and other blood born infections all thallsemai patients should be immunized with hepatitis B vaccine if patients are screnegative for HIV infection.
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