Inhibition growth of Candida albicans which isolated from renal failure and controlling by silver nanoparticles extracted from Syzygium aromaticum

Abstract

The samples of C. albicans were selected for  a sensitivity test with three concentrations were selected, as follows (50 ,100 ,200) mg/L. the upper inhibition zone is 200 mg/L which increased as compared with other concentrations, the inhibition percentage used to compare between all data using SPSS V.25 computer software using a T-test. P - values of less than 0.05 was considered statistically significant. Green synthesis using to produce silver nanoparticles by Syzygium aromaticum after adding the plant extract obtained of a silver nanoparticles when  adding  4ml extract of S. aromaticum and  the best pH to produce (AgNps) is 8 with wavelength 435 nm and 1 molarity by UV-visible devise. Field emission-scanning electron microscope (FESEM) revealed damage of the cells and inhibition biofilm formation of C.albicans when treated with AgNPs produce by S. aromaticum   as compared with control of  C.albicans which un treated with AgNPs,the inhibition growth diameter is 19mm  when using 200 mg/L caused the upper inhibition zone as compared with other concentrations.