Variation of histopathological features in colonic mucosal biopsy with clinical diagnosis of suspicious inflammatory bowel disease in Dr. Soetomo General Academic Hospital, Surabaya period 2015 - 2019
Keywords:
IBD, colonic biopsy histopathological, suspicious inflammatoryAbstract
Inflammatory bowel diseases (IBDs) are chronic inflammatory diseases that often relapse and divided into two types, Crohn’s disease (CD) and ulcerative colitis (UC). Histopathological findings in colonic mucosal biopsy with clinical diagnosis suspicious IBD can vary and overlap. Therefore, criteria and guidelines have been created to improve the diagnostic accuracy. This descriptive observational study was performed retrospectively with cross sectional approach. 122 samples of colonic mucosal biopsies with clinical diagnosis of suspicious IBD were retrieved from histopathological archives in the Anatomical Pathology Laboratorium of Dr. Soetomo Hospital, Surabaya during period 1st January 2015 - 31st December 2019. The most common histopathological feature found in colonic mucosal biopsies with clinical diagnosis of suspicious IBD was crypt distortion (97/79.50% samples), and the least was irregularity of surface epithelium (30/24.59% samples). 10 of 122 samples was concordant with the final diagnosis of IBD. Knowledges regarding the variations of histopathological features in colonic mucosal biopsy specimens with clinical diagnosis of suspicious IBD, can improve the diagnostic accuracy.
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Alatab, S., Sepanlou, S., Ikuta, K., Homayoon, V., Bisignano, C., & Safiri, S. (2020). The global, regional, and national burden of inflammatory bowel disease in 195 countries and territories, 1990–2017: A systematic analysis for the Global Burden of Disease Study 2017. The Lancet Gastroenterology and Hepatology, 5(1), 17–30.
Assarzadegan, N., Montgomery, E., & Pezhouh, M. K. (2017). Colitides: diagnostic challenges and a pattern based approach to differential diagnosis. Diagnostic Histopathology, 23(12), 536–543.
Avisiena A, Nusi IA, Maimunah U, Rahaju AS, Setiawan PB, Purbayu H, Widodo B, Miftahussurur M, Vidyani A, Thamrin H. (2019) Diagnostic values of helicobacter pylori stool antigen immunochromatographic method compared to histopathology in dyspepsia patient. The New Armenian Medical Journal, 13(1), 13-19.
Bates, A. W. H. (2012). Diagnosing eosinophilic colitis: Histopathological pattern or nosological entity? Scientifica, 12, 1–9.
Canavese, G., Villanacci, V., Antonelli, E., Cadei, M., Sapino, A., Rocca, R., Daperno, M., Suriani, R., Di Santo, M. G., Cassoni, P., Bernardini, N., & Bassotti, G. (2017). Eosinophilia – associated basal plasmacytosis: An early and sensitive histologic feature of inflammatory bowel disease. Apmis, 125(3), 179–183.
Dhakhwa, R., Shrestha, H., & Acharya, I. (2016). Histopathological evaluation of ulcerative colitis in colonoscopic biopsies. Journal of Pathology of Nepal, 6(11), 932–936.
Emara, M. H., Salama, R. I., Hamed, E. F., Shoriet, H. N., & Abdel-Aziz, H. R. (2019). Non-specific colitis among patients with colitis: Frequency and relation to inflammatory bowel disease, a prospective study. Journal of Coloproctology. Sociedade Brasileira de Coloproctologia, 39(4), 319–325.
Farmer, M., Petras, R. E., Hunt, L. E., Janosky, J. E., & Galandiuk, S. (2000). The importance of diagnostic accuracy in colonic inflammatory bowel disease. American Journal of Gastroenterology, 95(11), 3184–3188.
Fatimah S, Rahaju AS, Rahniayu A. (2021) Role of Claudin-4 and Matrix Metalloproteinase-2 in Tumor Invasion of Colorectal Adenocarcinoma. Research Journal of Pharmacy and Technology, 14(9), 4795.
Feakins, R. M. (2013). Inflammatory bowel disease biopsies: Updated British Society of Gastroenterology reporting guidelines. Journal of Clinical Pathology, 66(12), 1005–1026.
Gajendran, M., Loganathan, P., Jimenez, G., Catinella, A. P., Ng, N., Umapathy, C., Ziade, N., & Hashash, J. G. (2019). A comprehensive review and update on ulcerative colitis. Elsevier Inc., 65(12), 100851.
Geboes, K., & Van Eyken, P. (2009). Inflammatory bowel disease unclassified and indeterminate colitis: The role of the pathologist. Journal of Clinical Pathology, 62(3), 201–205.
Jenkins, D., Balsitis, M., Gallivan, S., Dixon, M. F., Gilmour, H. M., Shepherd, N. A., Theodossi, A., & Williams, G. T. (1997). Guidelines for the initial biopsy diagnosis of suspected chronic idiopathic inflammatory bowel disease. The British Society of Gastroenterology Initiative. Journal of Clinical Pathology, 50(2), 93–105.
Kalishah, J., Husada, D., Arfijanto, M. V., & Wahyu Widodo, A. D. (2022). Biofilm Formation and Antimicrobial Resistance of Escherichia coli in vitro Towards Ceftriaxone and Cefixime. Current Internal Medicine Research and Practice Surabaya Journal, 3(1), 5–8.
Kellermann, L., & Riis, L. B. (2021). A close view on histopathological changes in inflammatory bowel disease, a narrative review. Digestive Medicine Research, 4, 3–3.
Lang-Schwarz, C., Agaimy, A., Atreya, R., Becker, C., Danese, S., Fléjou, J. F., Gaßler. N., Grabsch, H. I., Hartmann, A., Kamarádová, K., Kühl, A. A., Lauwers, G. Y., Lugli, A., Nagtegaal, I., Neurath, M. F., Oberhuber, G., Peyrin-Biroulet, L., Rath, T., Riddell, R., Rubio, C. A., Sheahan, K., Tilg, H., Villanacci, V., Westerhoff, M., & Vieth, M. (2021). Maximizing the diagnostic information from biopsies in chronic inflammatory bowel diseases: Recommendations from the Erlangen International Consensus Conference on inflammatory bowel diseases and presentation of the IBD-DCA score as a proposal for a new i. Virchows Archiv, 478(3), 581–594.
Montgomery, E., Voltaggio, L., & Canto, M. I. (2012). Much ado about very little (lamina propria)? Gastrointestinal Endoscopy, 75(1), 19–22.
Ng, S. C. (2014). Epidemiology of inflammatory bowel disease: Focus on Asia. Best Practice and Research: Clinical Gastroenterology, 28(3), 363–372.
Ng, W. K., Wong, S. H., & Ng, S. C. (2016). Changing epidemiological trends of inflammatory bowel disease in Asia. Intestinal Research, 14(2), 111–119.
Nielson, O. H., and Seidelin, J. B. (2012). Non-IBD and noninfectious colitis. Geriatric Gastroenterology, 493–499.
Odze, R. D. & Goldblum, J. R. (2015). Surgical pathology of the GI tract, liver, biliary tract and pancreas, surgical pathology of the GI tract, liver, biliary tract, and pancreas.
Puspitarini, E. D., Prijambodo, P. (2022). Relationship between Sarcopenia in Abdomen CT Scan Results with C-Reactive Protein Level in Colorectal Cancer Patients at Dr. Soetomo General Academic Hospital Surabaya. Biomolecular and Health Science Journal, 5(1), 42–46.
Sattianayagam, P. T., Hawkins, P. N., &Gillmore, J. D. (2009). Systemic amyloidosis and the gastrointestinal tract. Nature Reviews Gastroenterology and Hepatology. Nature Publishing Group, 6(10), 608–617.
Saverymuttu, S. H., Hodgson, H. J. F., Chadwick, V. S., & Pepys, M. B. (1986). Differing acute phase responses in Crohn’s disease and ulcerative colitis. Gut, 27(7), 809–813.
Simadibrata, M., & Adiwinata, R. (2017). Current issues of gastroenterology in Indonesia. Acta medica Indonesiana, 49(3), 270–278.
Singh, R., Balekuduru, A., Simon, E. G., Alexander, M., & Pulimood, A. (2015). The differentiation of amebic colitis from inflammatory bowel disease on endoscopic mucosal biopsies. Indian Journal of Pathology and Microbiology, 58(4), 427–432.
Surawicz, C. M., & Belic, L. (1984). Rectal biopsy helps to distinguish acute self-limited colitis from idiopathic inflammatory bowel disease. Gastroenterology, 86(1), 104–113.
Turner, K., Genta, R. M., Lujan, G., Robiou, C., & Sonnenberg, A. (2014). Significance of the epithelioid granuloma in biopsies of Crohn’s colitis. Inflammatory Bowel Diseases, 20(12), 2271–2275.
Val, J. H. (2011). Old-age inflammatory bowel disease onset: A different problem? World Journal of Gastroenterology, 17(22), 2734–2739.
Villanacci, V., Reggiani-Bonetti, L., Caprioli, F., Saragoni, L., Salviato, T., Mescoli, C., Canavese, G., Manenti, S., Spada, E., Baron, L., Leoncini, G., Cadei, M., Battista, S., & Armuzzi, A. (2020). Histopathology of inflammatory bowel disease — Position statement of the pathologists of the Italian Group for the Study of Inflammatory Bowel Disease (IG-IBD) and Italian Group of Gastrointestinal Pathologists (GIPAD-SIAPEC). Digestive and Liver Disease. Editrice Gastroenterologica Italiana, 52(3), 262–267.
Villanacci, V., Reggiani-Bonetti, L., Salviato, T., Leoncini, G., Cadei, M., Albarello, L., Caputo, A., Aquilano, M. C., & Battista, S. (2021). Histopathology of IBD Colitis. A practical approach from the pathologists of the Italian Group for the study of the gastrointestinal tract (GIPAD). Digestive and Liver Disease. Editrice Gastroenterologica Italiana, 39–53.
Walker, M. M., Potter, M. D., & Talley, N. J. (2019). Eosinophilic colitis and colonic eosinophilia. Current Opinion in Gastroenterology, 35(1), 42–50.
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