Review on nutritional composition, bioactive compounds and therapeutic properties of Hippophae rhamnoides L. (Sea Buckthorn)
Keywords:
sitosterol, palmitoleic acid, catechin, polyphenols, carotenoidsAbstract
Hippophae rhamnoides L. (Sea Buckthorn) is a valuable multifunction plant largely distributed in Europe and Asia. In particular, the berries of sea buckthorn have been widely used as a food source like jam, juices, etc. The berry and seed of this plant are the main sources for its therapeutic and nutritional values. Thus, the plant has been extensively investigated for both of its nutritional and bioactive constituents. In general, the berries of this plant are rich in vitamins (C, E and K); while the ascorbic acid has been reported to be the primary vitamin, contributing to the acidic nature of the berries. Sea buckthorn berries also contain good amount of minerals like calcium and iron. On the other hand, the seed of sea buckthorn offers an excellent source of polyunsaturated fatty acids like palmitic acid, oleic acid and palmitoleic acid. Significant bioactive constituents in sea buckthorn including sitosterol, salicylic acid, tritepenoid, catechin, gallocatechin, epigallocatechin and carotenoids help in combating many diseases like cardiovascular diseases (angina), inflammation, cancer, gastric ulcer and epidermis issues. This review compiled the applications of sea buckthorn including a database of its nutritional and bioactive compounds which ultimately contribute towards the health promoting properties.
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References
Bal LM, Meda V, Naik SN, Satya S. Sea buckthorn berries: A potential source of valuable nutrients for nutraceuticals and cosmoceuticals. Food Research International. 2011;44(7):1718-1727.
Bittová M, Krejzová E, Roblová V, Kubáň P, Kubáň V. Monitoring of HPLC profiles of selected polyphenolic compounds in sea buckthorn (Hippophaë rhamnoides L.) plant parts during annual growth cycle and estimation of their antioxidant potential. Open Chemistry. 2014;12(11):1152-1161.
Chandra S, Zafar R, Dwivedi P, Shinde LP, Prita B. Pharmacological and nutritional importance of sea buckthorn (Hippophae). The Pharma Innovation. 2018;7(5):258-263.
Christaki E. Hippophae rhamnoides L. (Sea Buckthorn): a potential source of nutraceuticals. Food Public Health. 2012;2(3):69-72.
Crăciun I. Comparitive Study of Liposoluble Vitamins and Fatty Acids from Sea Buckthorn Oil, Wheat Germ Oil and Fish Oil. Acta Universitatis Cinbinesis, Series E: Food Technology. 2018;22(2):85-90.
Criste A, Urcan AC, Bunea A, Pripon Furtuna FR, Olah NK, Madden RH, Corcionivoschi N. Phytochemical composition and biological activity of berries and leaves from four Romanian sea buckthorn (Hippophae rhamnoides L.) varieties. Molecules. 2020;25(5):1170.
Daško L, Drímal J, Klimeková M, Ürgeová E. Response of organically and conventionally produced potatoes to a controlled attack of a pathogen. Journal of Food and Nutrition Research. 2012;51(2):89-95.
Dulf FV. Fatty acids in berry lipids of six sea buckthorn (Hippophae rhamnoides L., subspecies carpatica) cultivars grown in Romania. Chemistry Central Journal. 2012;6(1):1-12.
Edraki M, Akbarzadeh A, Hosseinzadeh M, Tanideh N, Salehi A, Koohi-Hosseinabadi O. Healing effect of sea buckthorn, olive oil, and their mixture on full-thickness burn wounds. Advances in skin & wound care. 2014;27(7):317-323.
Fan XM, Shen XL, Yan LL, Wang XC, Yin JT. The contents of quercetin, kaempferol and isorhamnetin in the fruit of Hippophae rhamnoides were determined by HPLC. Chinese Journal of Hospital Pharmacy. 2012; 32(17):1343–1346.
Fatima T, Snyder CL, Schroeder WR, Cram D, Datla R, Wishart D, Weselake RJ, Krishna P. Fatty acid composition of developing sea buckthorn (Hippophae rhamnoides L.) berry and the transcriptome of the mature seed. PloS one. 2012;7(4):e34099.
García VL. The omega 7 as a health strategy for the skin and mucous membranes. EC Nutrition. 2019; 14:484-489.
Guo XF, Yang B, Cai W, Li D. Effect of sea buckthorn (Hippophae rhamnoides L.) on blood lipid profiles: a systematic review and meta-analysis from 11 independent randomized controlled trials. Trends in Food Science & Technology. 2017; 61:1-10.
Heinaaho M, Julkunen-Tiitto R. Efficient extraction of flavonoids of sea buckthorn berries. BioChemistry: An Indian Journal. 2011; 5:83-87.
Hussain M, Ali S, Awan S, Hussain M, Hussain I. Analysis of minerals and vitamins in sea buckthorn (Hippophae rhamnoides) pulp collected from Ghizer and Skardu districts of Gilgit-Baltistan. International Journal of Bioscience. 2014; 4:144-152.
Ivanišová E, Mittuchová K, Mareček J, Frančáková H. Small Berries–Attractive Source of Bioactive Compounds for Consumers. Agrobiodiversity for Improving Nutrition, Health and Life Quality. 2017; 1:188-194.
Koyama T, Taka A, Togashi H. Effects of a herbal medicine, Hippophae rhamnoides, on cardiovascular functions and coronary microvessels in the spontaneously hypertensive stroke-prone rat. Clinical Hemorheology and Microcirculation. 2009;41(1):17-26.
Larmo PS, Yang B, Hurme SA, Alin JA, Kallio HP, Salminen EK, Tahvonen RL. Effect of a low dose of sea buckthorn berries on circulating concentrations of cholesterol, triacylglycerols, and flavonols in healthy adults. European Journal of Nutrition. 2009;48(5):277-282.
Larmo PS, Yang B, Hyssälä J, Kallio HP, Erkkola R. Effects of sea buckthorn oil intake on vaginal atrophy in postmenopausal women: a randomized, double-blind, placebo-controlled study. Maturitas. 2014;79(3):316-321.
Leskinen HM, Suomela JP, Yang B, Kallio HP. Regioisomer compositions of vaccenic and oleic acid containing triacylglycerols in sea buckthorn (Hippophae rhamnoides) pulp oils: influence of origin and weather conditions. Journal of Agricultural and Food chemistry. 2010;58(1):537-645.
Lu SG, Lu J, X F. Wen. Review on plant resources distribution and nutrition application of sea buckthorn. Soil and Water Conservation in China SWCC. 2019; 7:45–49.
Marsiñach MS, Cuenca AP. The impact of sea buckthorn oil fatty acids on human health. Lipids in health and disease. 2019;18(1):1-11.
Michel T, Destandau E, Le Floch G, Lucchesi ME, Elfakir C. Antimicrobial, antioxidant and phytochemical investigations of sea buckthorn (Hippophaë rhamnoides L.) leaf, stem, root and seed. Food Chemistry. 2012;131(3):754-760.
Nazir F, Bashir M. Chemical and antioxidant properties of Sea buckthorn (Hippophae rhamnoides). The Pharma Innovation Journal. 2017;6(12):173-176.
Nour V, Panaite TD, Corbu AR, Ropota M, Turcu RP. Nutritional and bioactive compounds in dried sea-buckthorn pomace. Erwerbs-Obstbau. 2021;63(1):91-98.
Padmavathi B, Upreti M, Singh V, Rao AR, Singh RP, Rath PC. Chemoprevention by Hippophae rhamnoides: effects on tumorigenesis, phase II and antioxidant enzymes, and IRF-1 transcription factor. Nutrition and Cancer. 2005;51(1):59-67.
Patel CA, Divakar K, Santani D, Solanki HK, Thakkar JH. Remedial prospective of Hippophae rhamnoides Linn. (sea buckthorn). International Scholarly Research Notices.2012.
Pentelescu C, Pop DM, Colceriu L, Deleanu A. Use of Sea-buckthorn (Hippophae rhamnoides) in the Treatment of Acute Gingivitis. Medicine and Pharmacy Reports. 2012;85(2):254-259.
Pop EA, Diaconeasa ZM, Fetea F, Bunea A, Dulf F, Pintea A, Socaciu C. Carotenoids, tocopherols and antioxidant activity of lipophilic extracts from sea buckthorn berries (Hippophae rhamnoides), apricot pulp and apricot kernel (Prunus armeniaca). Bulletin UASVM Food Science and Technology. 2015;72(2):14-21.
Pop RM, Weesepoel Y, Socaciu C, Pintea A, Vincken JP, Gruppen H. Carotenoid composition of berries and leaves from six Romanian sea buckthorn (Hippophae rhamnoides L.) varieties. Food Chemistry. 2014; 147:1-9.
Preedy VR, editor. Handbook of Nutrition, Diet, and the Eye. Academic Press. 2014.
Rop O, Ercişli S, Mlcek J, Jurikova T, Hoza I. Antioxidant and radical scavenging activities in fruits of 6 sea buckthorn (Hippophae rhamnoides L.) cultivars. Turkish Journal of Agriculture and Forestry. 2014;38(2):224-232.
Ranjith A, Kumar KS, Venugopalan VV, Arumughan C, Sawhney RC, Singh V. Fatty acids, tocols, and carotenoids in pulp oil of three sea buckthorn species (Hippophae rhamnoides, H. salicifolia, and H. tibetana) grown in the Indian Himalayas. Journal of the American Oil Chemists Society. 2006;83(4):359-364.
Rashid A, Raisuddin A, Kumar ND, Abhinav J, Amit T, Gaurav M, Aseem B. Safety and efficacy study of intramuscularly administered sea buckthorn (Hippophae rhamnoides L.) oil as depot formulation. International Journal of Drug Development & Research. 2011;3(3):356-365.
Sayegh M, Miglio C, Ray S. Potential cardiovascular implications of Sea Buckthorn berry consumption in humans. International Journal of Food Sciences and Nutrition. 2014;65(5):521-528.
Singh IP, Ahmad F, Gore DD, Tikoo K, Bansal A, Jachak SM, Jena G. Therapeutic potential of seabuckthorn: a patent review (2000-2018). Expert Opinion on Therapeutic Patents. 2019;29(9):733-744.
Stobdan T, Korekar G, B Srivastava R. Nutritional attributes and health application of seabuckthorn (Hippophae rhamnoides L.)-A review. Current Nutrition & Food Science. 2013;9(2):151-165.
Süleyman H, Demirezer LÖ, Büyükokuroglu ME, Akcay MF, Gepdiremen A, Banoglu ZN, Göçer F. Antiulcerogenic effect of Hippophae rhamnoides L. Phytotherapy Research. 2001;15(7):625-627.
Suryakumar G, Gupta A. Medicinal and therapeutic potential of Sea buckthorn (Hippophae rhamnoides L.). Journal of Ethnopharmacology. 2011;138: 268- 278.
Teleszko M, Wojdyło A, Rudzinska M, Oszmianski J, Golis T. Analysis of lipophilic and hydrophilic bioactive compounds content in sea buckthorn (Hippophae rhamnoides L.) berries. Journal of Agricultural and Food Chemistry. 2015;63(16):4120-4129.
Tkacz K, Wojdyło A, Turkiewicz IP, Bobak Ł, Nowicka P. Anti-oxidant and anti-enzymatic activities of sea buckthorn (Hippophaë rhamnoides L.) fruits modulated by chemical components. Antioxidants. 2019;8(12):618.
Trineeva OV, Safonova EF, Sinkevich AV, Slivkin AI. Assay of amino acids in medicinal plants by TLC (using stinging nettle leaves and common sea buckthorn fruits as examples). Pharmaceutical Chemistry Journal. 2015;49(5):323-328.
Vaitkeviciene N, Danilcenko H, Mazeika R, Jariene E, Vaitkeviciene N, Kulaitiene J, Hallmann E, Blinstrubien A. Comparison of mineral and fatty acid composition of wild and cultivated sea buckthorn berries from Lithuania. Journal of Elementology. 2019;24(3):1101–1113.
Wang K, Xu Z, Liao X. Bioactive compounds, health benefits and functional food products of sea buckthorn: A review. Critical Reviews in Food Science and Nutrition. 2021:1-22.
Wani TA, Wani SM, Ahmad M, Ahmad M, Gani A, Masoodi FA. Bioactive profile, health benefits and safety evaluation of sea buckthorn (Hippophae rhamnoides L.): A review. Cogent Food & Agriculture. 2016;2(1):1128519.
Wen P, Zhao P, Qin G, Tang S, Li B, Zhang J, Peng L. Genotoxicity and teratogenicity of seabuckthorn (Hippophae rhamnoides L.) berry oil. Drug and Chemical Toxicology. 2020;43(4):391-377.
Wu ZJ, Ruan CJ, Li H, Yang ML, Xie MM, Xiao TT. Compositions of Soluble Sugars and Organic Acids in Berries of 12 Sea-buckthorn Cultivars. Journal of Northwest Forestry University. 2016; 4:106-112.
Xu YJ, Kaur M, Dhillon RS, Tappia PS, Dhalla NS. Health benefits of sea buckthorn for the prevention of cardiovascular diseases. Journal of functional foods. 2011;3(1):2-12
Yasukawa K, Kitanaka S, Kawata K, Goto K. Anti-tumor promoters phenolics and triterpenoid from Hippophae rhamnoides. Fitoterapia. 2009;80(3):164-167.
Zakynthinos G, Varzakas T. Hippophae rhamnoides: safety and nutrition. Current Research in Nutrition and Food Science Journal. 2015;3(2):89-97.
Zhao P, Wang S, Liang C, Wang Y, Wen P, Wang F, Qin G. Acute and subchronic toxicity studies of seabuckthorn (Hippophae rhamnoides L.) oil in rodents. Regulatory Toxicology and Pharmacology. 2017; 91:50-57.
Zielińska A, Nowak I. Abundance of active ingredients in sea-buckthorn oil. Lipids in Health and Disease. 2017;16(1):1-11.
Suryasa, W., Sudipa, I. N., Puspani, I. A. M., & Netra, I. (2019). Towards a Change of Emotion in Translation of Kṛṣṇa Text. Journal of Advanced Research in Dynamical and Control Systems, 11(2), 1221-1231.
Suwija, N., Suarta, M., Suparsa, N., Alit Geria, A.A.G., Suryasa, W. (2019). Balinese speech system towards speaker social behavior. Humanities & Social Sciences Reviews, 7(5), 32-40. https://doi.org/10.18510/hssr.2019.754
Gandamayu, I. B. M., Antari, N. W. S., & Strisanti, I. A. S. (2022). The level of community compliance in implementing health protocols to prevent the spread of COVID-19. International Journal of Health & Medical Sciences, 5(2), 177-182. https://doi.org/10.21744/ijhms.v5n2.1897
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