The protective role of almond and thyme in carbonated beverage-induced osteoporosis in male albino rats

Mustafa Adnan Zeyadi; Fares K. Khalifa

doi:10.53730/ijhs.v6nS5.8776

Authors

Mustafa Adnan Zeyadi Department of Biochemistry, Faculty of Science, King Abdul-Aziz University
Fares K. Khalifa Department of Biochemistry, Faculty of Science, King Abdul-Aziz University & Department of Biochemistry and Nutrition, Faculty of Women for Arts, Science, and Education, Ain Shams University, Cairo, Egypt

Abstract

Osteoporosis is a common health problem distinguished by low bone mass and microarchitectural deterioration of bone tissue, thus increase bone fragility and fracture. Nutrition possesses a critical role in reducing osteoporosis risks among its impact on fragility factors, particularly on bone mass development and maintenance. The current study was carried out to assess and compare the protective effect of almond and thyme against osteoporosis induced by excessive intake of carbonated beverage (Coca-Cola) in rats. Forty-eight adult male Sprague–Dawley rats were divided into six groups: G1, control negative fed balanced diet; G2, control positive fed balanced diet and received Coca-Cola orally by gavage (20 ml/day) (CB); G3, almond powder (5g/100g diet) (A); G4, thyme powder (5g/100g diet) (T) and G5, (CB) +(A); 6, (CB)+(T)). Almond and thyme supplementation significantly reduced the development of osteoporosis as well as inflammation and oxidative stress. Our findings show that almond and thyme can effectively reduce soft drink-induced bone loss and could be used as dietary supplements to prevent bone resorption and osteoporosis.

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