Efficacy of combination of multinutrients in reduction of sperm DNA fragmentation

https://doi.org/10.53730/ijhs.v6nS3.8857

Authors

  • Asha Arora HOD, Department of Biotechnology, BN University, Udaipur | Research Scholar, Department of Biotechnology, BN University, Udaipur
  • Dhiraj Singh Ranawat HOD, Department of Biotechnology, BN University, Udaipur | Research Scholar, Department of Biotechnology, BN University, Udaipur
  • Vivek Dave HOD, Department of Biotechnology, BN University, Udaipur | Research Scholar, Department of Biotechnology, BN University, Udaipur
  • Chhavi Pandya HOD, Department of Biotechnology, BN University, Udaipur | Research Scholar, Department of Biotechnology, BN University, Udaipur
  • Krishna Kawar Rathore HOD, Department of Biotechnology, BN University, Udaipur | Research Scholar, Department of Biotechnology, BN University, Udaipur
  • Rahul HOD, Department of Biotechnology, BN University, Udaipur | Research Scholar, Department of Biotechnology, BN University, Udaipur

Keywords:

DNA fragmentation, Co-Q10 tablets, male in fertility

Abstract

High Sperm DNA fragmentation can cause decreased fertility & implantation rate or can cause Recurrent implantation failure and if fetus born then can lead to Genetic abnormality in the fetus such as Down Syndrome, Edward syndrome or Patau’s syndrome. The objective of the study is to combine the peripheral data of the patients to evaluate the safety and efficacy of Combination tablet in reduction of Sperm DNA fragmentation index. The result shows that the factors affecting the DFI .The Institutional Ethics Committee approved the study procedure (Ref No: SRMC/RP/4505).

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References

Agarwal, A., Mulgund, A., Hamada, A., & Chyatte, M. R. (2015). A unique view on male infertility around the globe. Reproductive biology and endocrinology, 13(1), 1-9.

Prangthip, P., Kettawan, A., Posuwan, J., Okuno, M., & Okamoto, T. (2016). An improvement of oxidative stress in diabetic rats by ubiquinone-10 and ubiquinol-10 and bioavailability after short-and long-term coenzyme Q10 supplementation. Journal of dietary supplements, 13(6), 647-659.

Nadjarzadeh, A., Sadeghi, M. R., Amirjannati, N., Vafa, M. R., Motevalian, S. A., Gohari, M. R., ...& Shidfar, F. (2011). Coenzyme Q10 improves seminal oxidative defense but does not affect on semen parameters in idiopathic oligoasthenoteratozoospermia: a randomized double-blind, placebo controlled trial. Journal of endocrinological investigation, 34(8), e224-e228.

Eroglu, M., Sahin, S., Durukan, B., Ozakpinar, O. B., Erdinc, N., Turkgeldi, L., ... & Karateke, A. (2014). Blood serum and seminal plasma selenium, total antioxidant capacity and coenzyme q10 levels in relation to semen parameters in men with idiopathic infertility. Biological trace element research, 159(1), 46-51.

Langsjoen, P. H., & Langsjoen, A. M. (2014). Comparison study of plasma coenzyme Q10 levels in healthy subjects supplemented with ubiquinol versus ubiquinone. Clinical pharmacology in drug development, 3(1), 13-17.

Barakat, A., Shegokar, R., Dittgen, M., & Müller, R. H. (2013). Coenzyme Q10 oral bioavailability: effect of formulation type. Journal of Pharmaceutical Investigation, 43(6), 431-451.

Cito, G., Cocci, A., Micelli, E., Gabutti, A., Russo, G. I., Coccia, M. E., ... & Natali, A. (2020). Vitamin D and male fertility: an updated review. The world journal of men's health, 38(2), 164-177.

Rinartha, K., Suryasa, W., & Kartika, L. G. S. (2018). Comparative Analysis of String Similarity on Dynamic Query Suggestions. In 2018 Electrical Power, Electronics, Communications, Controls and Informatics Seminar (EECCIS) (pp. 399-404). IEEE.

Suryasa, I. W., Rodríguez-Gámez, M., & Koldoris, T. (2021). Get vaccinated when it is your turn and follow the local guidelines. International Journal of Health Sciences, 5(3), x-xv. https://doi.org/10.53730/ijhs.v5n3.2938

Damayanti, I. A. M., Indrayoni, P., Antari, N. W. S., & Padmiswari, A. A. I. M. (2021). Effectiveness of Averrhoa bilimbi leaf extract on spermatogenic cells of mice (Mus Musculus L.) hyperglycemia. International Journal of Health & Medical Sciences, 4(2), 273-279. https://doi.org/10.21744/ijhms.v4n2.1747

Published

12-06-2022

How to Cite

Arora, A., Ranawat, D. S., Dave, V., Pandya, C., Rathore, K. K., & Rahul, R. (2022). Efficacy of combination of multinutrients in reduction of sperm DNA fragmentation. International Journal of Health Sciences, 6(S3), 11782–11789. https://doi.org/10.53730/ijhs.v6nS3.8857

Issue

Section

Peer Review Articles