To compare the effect of non-steroidal anti-inflammatory drugs (NSAIDS) and opioids in KNEE pain

Karunakar Dwivedi; Jamil Raazi; Ayesha Kriti Rahman

doi:10.53730/ijhs.v6nS3.8946

To compare the effect of non-steroidal anti-inflammatory drugs (NSAIDS) and opioids in KNEE pain

https://doi.org/10.53730/ijhs.v6nS3.8946

Authors

Karunakar Dwivedi Associate Professor, Department of Orthopaedics, Moti Lal Nehru Medical College, Prayagraj
Jamil Raazi Assistant Professor, Department of Community Medicine, Rama Medical College Hospital & Research Centre, Kanpur
Ayesha Kriti Rahman Assistant Professor, Department of Community Medicine, Rama Medical College Hospital & Research Centre, Kanpur

Keywords:

osteoarthritis, NSAIDs, opioid

Abstract

Introduction: Osteoarthritis is a most painful condition mostly seen in old age people in knee and hip joints. This painful condition may causes change in physical activity and reduces quality of life. There are some topical and oral non steroidal anti-inflammatory drugs such as paracetamol, diclofenac sodium and opioid analgesic drugs tramadol. The main aims of the study compare the effect of NSAIDs and opioid analgesic in treatment of knee pain. Aim: To Compare The Effect of Non-Steroidal Anti-Inflammatory Drugs (NSAIDS) and Opioid In Reducing Knee Pain. Materials and Methods: The present was conducted at Moti Lal Nehru Medical College, Prayagraj in orthopedics department. Total of 50 patients were included in the study aged 40-60 years. Results: Patients were prescribed with NSAIDs such as paracetamol prescribed to 4 patients, diclofenac 13 patients, ibuprofen 8 patients and opioid analgesic Oxycodone 07 patients, Acetaminophen/hydrocodone 14 patients and tramadol 04 patients. Patients were followed for every 15 days. On the 1^st visit after prescribing paracetamol 0 patients were got relief from the pain, diclofenac 3 patients, ibuprofen 02 patients, Oxycodene 0 patients, Hydrocodene 04 patients, tramadol 01 patient.

Downloads

Download data is not yet available.

References

Altman R, Brandt K, Hochberg M, et al. Design and conduct of clinical trials in patients with osteoarthritis: recommendations from a task force of the Osteoarthritis Research Society. Results from a workshop. Osteoarthritis Cartilage 1996;4:217-43.

Larochelle MR, Zhang F, Ross-Degnan D, Wharam JF. Trends in opioid prescribing and co-prescribing of sedative hypnotics for acute and chronic musculoskeletal pain: 2001-2010. Pharmacoepidemiol Drug Saf 2015;24:885-92.

Taqi A, Otete H, Knaggs R. Trends in opioid prescribing in primary care patients with knee osteoarthritis: a population based observational study. Value Health 2017;20:A540-1. doi:10.1016/j.

Bruno R da Costa,1,2,3 Tiago V Pereira,1,4 Pakeezah Saadat, et al. Effectiveness and safety of non-steroidal anti-inflammatory drugs and opioid treatment for knee and hip osteoarthritis: network. BMJ. 2021;375 (1):n2321

Jevsevar DS, Brown GA, Jones DL, Matzkin EG, Manner PA, Mooar P, et al. The American Academy of Orthopaedic Surgeons evidence-based guideline on: treatment of osteoarthritis of the knee, 2nd edition. J Bone Joint Surg Am 2013;95:1885e6.

J.M.Jordan et al. Cost-effectiveness of nonsteroidal anti-inflammatory drugs and opioids in the treatment of knee osteoarthritis in older patients with multiple comorbidities. Osteoarthritis Research Society International. 2016; 24(3):409-418.

S R Smith et al. Comparative pain reduction of oral non-steroidal anti-inflammatory drugs and opioids for knee osteoarthritis: systematic analytic review. Osteoarthritis Cartilage. 2016;24(6):962-72.

Suryasa, I. W., Rodríguez-Gámez, M., & Koldoris, T. (2021). Health and treatment of diabetes mellitus. International Journal of Health Sciences, 5(1), i-v. https://doi.org/10.53730/ijhs.v5n1.2864

Suryasa, I. W., Rodríguez-Gámez, M., & Koldoris, T. (2021). The COVID-19 pandemic. International Journal of Health Sciences, 5(2), vi-ix. https://doi.org/10.53730/ijhs.v5n2.2937

Tursunova, M. O., Khaydarov, N. K., Abdullaeva, M. B., Abdukodirov, E. I., & Nazarova, M. F. (2021). Significance of transient ischemic attacks (TIA) in the development and course of ischemic strokes. International Journal of Health & Medical Sciences, 4(2), 215-219. https://doi.org/10.31295/ijhms.v4n2.1703

Published

14-06-2022

How to Cite

Dwivedi, K., Raazi, J., & Rahman, A. K. (2022). To compare the effect of non-steroidal anti-inflammatory drugs (NSAIDS) and opioids in KNEE pain. International Journal of Health Sciences, 6(S3), 11875–11881. https://doi.org/10.53730/ijhs.v6nS3.8946

Download Citation

Issue

Vol. 6 No. S3 (2022)

Section

Peer Review Articles

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Articles published in the International Journal of Health Sciences (IJHS) are available under Creative Commons Attribution Non-Commercial No Derivatives Licence (CC BY-NC-ND 4.0). Authors retain copyright in their work and grant IJHS right of first publication under CC BY-NC-ND 4.0. Users have the right to read, download, copy, distribute, print, search, or link to the full texts of articles in this journal, and to use them for any other lawful purpose.

Articles published in IJHS can be copied, communicated and shared in their published form for non-commercial purposes provided full attribution is given to the author and the journal. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.

This copyright notice applies to articles published in IJHS volumes 4 onwards. Please read about the copyright notices for previous volumes under Journal History.