Effect of calcium supplementation on weight loss in overweight and obese women, Baghdad, 2021

https://doi.org/10.53730/ijhs.v6nS2.8978

Authors

  • Ali Haleem Jasim M.B.Ch.B. C.A.B.H.S / Community Medicine, Membership of Clinical Nutrition, Ministry of Health / Minister's Office, Baghdad, Iraq
  • Besmah Mohammed Ali M.B.Ch.B. F.I.B.M.S. Consultant doctor, Specialist in Community Medicine, Head of Public Health Department in Ghazi Al-Hariri for Surgical Specialties, Baghdad Medical City, Ministry of Health, Baghdad, Iraq
  • Bushra Gatea Abbas M.B.Ch.B. F.I.C.M.S./ FM. Membership of clinical nutrition. Afak Primary Health Care Sector

Keywords:

obesity, overweight, calcium, weight loss, weight reduction

Abstract

Introduction: Obesity became a major public health burden worldwide and its prevalence rate in adults during the last forty years has been increasing in the developed and developing countries. Its prevalence among Iraqi women in 2020 was about 40%. Some studies suggested that calcium supplementation could accelerate weight loss and treat obesity. Objectives: To determine whether calcium intake during a weight loss program affects reduction of Iraqi women weight and whether there is a difference in the weight loss of both pre-menopausal and post-menopausal obese women after giving them calcium. Methods: An Interventional study was carried out on 50 overweight or obese Iraqi women "premenopausal or at least 3 years post-menopausal". They had been engaged in 6 month interventional program to reduce their weight through ingestion of calcium orally. Their BMI was measured in the beginning and in the end of that course. Results: The mean age among the participants was 45.4 ±17.3 years. 52% of them were premenopausal and 48% were postmenopausal. The reduction of BMI after 6 month calcium supplementation course was 74% among the whole women; which was significant, 88.5% among the premenopausal, which was also significant, and 58.3% among postmenopausal, which was not significant. 

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References

Collaboration, N.C.D.R.F. Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: A pooled analysis of 2416 population-based measurement studies in 128.9 million children, adolescents, and adults. Lancet 2017; 390, 2627–2642.

Upadhyay, J.; Farr, O.; Perakakis, N.; Ghaly, W.; Mantzoros, C. Obesity as a disease. Med. Clin. N. Am. 2018; 102, 13–33.

Kyrou, I.; Randeva, H.S.; Tsigos, C.; Kaltsas, G.; Weickert, M.O. Clinical Problems Caused by Obesity. In Endotext; Feingold, K.R., Anawalt, B., Boyce, A., Chrousos, G., Dungan, K., Eds.; MDText.com, Inc.: South Dartmouth, MA, USA, 2018.

Bray, G.A.; Kim, K.K.; Wilding, J.P.H. Obesity: A chronic relapsing progressive disease process. A position statement of the World Obesity Federation. Obes. Rev. 2017; 18, 715–723.

Czech, M.P. Insulin action and resistance in obesity and type 2 diabetes. Nat. Med. 2017; 23, 804–814.

Kahn, S.E.; Hull, R.L.; Utzschneider, K.M. Mechanisms linking obesity to insulin resistance and type 2 diabetes. Nature 2006; 444, 840–846.

Klop, B.; Elte, J.W.; Cabezas, M.C. Dyslipidemia in obesity: Mechanisms and potential targets. Nutrients 2013; 5, 1218–1240.

Howard, B.V.; Ruotolo, G.; Robbins, D.C. Obesity and dyslipidemia. Endocrinol. Metab. Clin. N. Am. 2003; 32, 855–867.

Seravalle, G.; Grassi, G. Obesity and hypertension. Pharmacol. Res. 2017; 122,1–7.

DeMarco, V.G.; Aroor, A.R.; Sowers, J.R. The pathophysiology of hypertension in patients with obesity. Nat. Rev. Endocrinol. 2014; 10, 364–376.

Ortega, F.B.; Lavie, C.J.; Blair, S.N. Obesity and Cardiovascular Disease. Circ. Res. 2016; 118, 1752–1770.

Mandviwala, T.; Khalid, U.; Deswal, A. Obesity and Cardiovascular Disease: A Risk Factor or a Risk Marker? Curr. Atheroscler. Rep. 2016; 18, 21.

Milic, S.; Lulic, D.; Stimac, D. Non-alcoholic fatty liver disease and obesity: Biochemical, metabolic and clinical presentations. World J. Gastroenterol. 2014; 20, 9330–9337.

Dietrich, P.; Hellerbrand, C. Non-alcoholic fatty liver disease, obesity and the metabolic syndrome. Best Pract. Clin. Gastroenterol. 2014; 28, 637–653.

Silvestris, E.; de Pergola, G.; Rosania, R.; Loverro, G. Obesity as disruptor of the female fertility. Reprod. Biol. Endocrinol. 2018; 16, 22.

Dimitriadis, G.K.; Barber, T.M. Obesity-related metabolic and reproductive dysfunction: Variations between the sexes. Expert Rev. Endocrinol. Metab. 2016; 11, 387–393.

Kahn, B.E.; Brannigan, R.E. Obesity and male infertility. Curr. Opin. Urol. 2017; 27, 441–445.

Ackerman, S.E.; Blackburn, O.A.; Marchildon, F.; Cohen, P. Insights into the Link between Obesity and Cancer. Curr. Obes. Rep. 2017; 6, 195–203.

Tahergorabi, Z.; Khazaei, M.; Moodi, M.; Chamani, E. From obesity to cancer: A review on proposed mechanisms. Cell Biochem. Funct. 2016; 34, 533–545.

Fallah-Fini, S.; Adam, A.; Cheskin, L.J.; Bartsch, S.M.; Lee, B.Y. The Additional Costs and Health Effects of a Patient Having Overweight or Obesity: A Computational Model. Obesity 2017; 25, 1809–1815.

Kim, D.D.; Basu, A. Estimating the Medical Care Costs of Obesity in the United States: Systematic Review, Meta-Analysis, and Empirical Analysis. Value Health 2016; 19, 602–613.

Fruh, S.M. Obesity: Risk factors, complications, and strategies for sustainable long-term weight management. J. Am. Assoc. Nurse Pract. 2017; 29, S3–14.

Swinburn, B.A.; Caterson, I.; Seidell, J.C.; James, W.P. Diet, nutrition and the prevention of excess weight gain and obesity. Public Health Nutr. 2004; 7, 123–146.

Koliaki, C.; Spinos, T.; Spinou, M.; Brinia Mu, E.; Mitsopoulou, D.; Katsilambros, N. Defining the Optimal Dietary Approach for Safe, Effective and Sustainable Weight Loss in Overweight and Obese Adults. Healthcare 2018; 6, 73.

Zulet, M.A.; Moreno-Aliaga, M.J.; Alfredo Martínez, J. Dietary determinants of fat mass and body composition. In Adipose Tissue Biology; Symonds, M.E., Ed.; Springer International Publishing: Cham, Switzerland, 2017; 319–382.

Lai, C.S.; Wu, J.C.; Pan, M.H. Molecular mechanism on functional food bioactives for anti-obesity. Curr. Opin. Food Sci. 2015; 2, 9–13.

Obesity among females in Al-Sader City Baghdad, Iraq, 2017 Hadeel M.Jasim, Hassan M.Abdul Hussein, Eman A. Al-Kaseer Journal of the Faculty of Medicine. 2018; 60 (2), 105-107.

Pengpid S, Peltzer K. Overweight and Obesity among Adults in Iraq: Prevalence and Correlates from a National Survey in 2015. Int J Environ Res Public Health. 2021;18 (8), 4198.

Global nutrition report. Country nutrition profiles. [Internet] 2022; available at: https://globalnutritionreport.org/resources/nutrition-profiles/asia/western-asia/iraq/.

Ye, J.; Ai, W.; Zhang, F.; Zhu, X.; Shu, G.; Wang, L.; Gao, P.; Xi, Q.; Zhang, Y.; Jiang, Q.; et al. Enhanced Proliferation of Porcine Bone Marrow Mesenchymal Stem Cells Induced by Extracellular Calcium is Associated with the Activation of the Calcium-Sensing Receptor and ERK Signaling Pathway. Stem Cells Int. 2016; 657-671.

Goudarzi, F.; Mohammadalipour, A.; Khodadadi, I.; Karimi, S.; Mostoli, R.; Bahabadi, M.; Goodarzi, M.T. The Role of Calcium in Differentiation of Human Adipose-Derived Stem Cells to Adipocytes. Mol. Biotechnol. 2018, 60, 279–289.

Pramme-Steinwachs, I.; Jastroch, M.; Ussar, S. Extracellular calcium modulates brown adipocyte differentiation and identity. Sci. Rep. 2017; 7, 8888.

Pannu, P.K.; Calton, E.K.; Soares, M.J. Calcium and Vitamin D in Obesity and Related Chronic Disease. Adv. Food Nutr. Res. 2016; 77, 57–100.

Onakpoya, I.J.; Perry, R.; Zhang, J.; Ernst, E. Efficacy of calcium supplementation for management of overweight and obesity: Systematic review of randomized clinical trials. Nutr. Rev. 2011; 69, 335–343.

Booth, A.O.; Huggins, C.E.; Wattanapenpaiboon, N.; Nowson, C.A. Effect of increasing dietary calcium through supplements and dairy food on body weight and body composition: A meta-analysis of randomized controlled trials. Br. J. Nutr. 2015; 114, 1013–1025.

Ismail, M.S.; Qahiz, N.M.A. Can Dietary Calcium Consumption be Beneficial in Body Weight Loss Regimen? Merit Res. J. Med. Med. Sci. 2016; 4, 282–289.

Chaturvedi, R.; Singh, N. Role of calcium in obesity: Does it help? CIBTech J. Zool. 2013, 2, 10–16. 40. Barba, G.; Russo, P. Dairy foods, dietary calcium and obesity: A short review of the evidence. Nutr. Metab. Cardiovasc. Dis. 2006; 16, 445–451.

Soares, M.J.; Ping-Delfos, W.C.S.; Ghanbari, M.H. Calcium and vitamin D for obesity: A review of randomized controlled trials. Eur. J. Clin. Nutr. 2011; 65, 994–1004.

Li, P.; Fan, C.; Lu, Y.; Qi, K. Effects of calcium supplementation on body weight: A meta-analysis. Am. J. Clin. Nutr. 2016; 104, 1263–1273.

Heaney, R.P.; Davies, K.M.; Barger-Lux, M.J. Calcium and weight: Clinical studies. J. Am. Coll. Nutr. 2002; 21, 152S–155S.

Institute of Medicine (US) Committee to Review Dietary Reference Intakes for Vitamin D and Calcium. The national academies collection: Reports funded by national institutes of health. In Dietary Reference Intakes for Calcium and Vitamin D; Ross, A.C., Taylor, C.L., Yaktine, A.L., Del Valle, H.B., Eds.; National Academies Press (US) National Academy of Sciences: Washington, DC, USA, 2011.

Zhu, W., Cai, D., Wang, Y. et al. Calcium plus vitamin D3 supplementation facilitated Fat loss in overweight and obese college students with very-low calcium consumption: a randomized controlled trial. Nutr J. 2013; 12, 8.

Efficacy of calcium supplementation for management of overweight and obesity: systematic review of randomized clinical trials Igho J nakpoya, Rachel Perry, Junhua Zhang, Edzard Ernst Nutrition Reviews. 2011; 69 (6) , 335- 43.

Effect of Calcium Supplementation on Weight and Fat Loss in Women ,Sue A. Shapses, Stanley Heshka, Steven B. Heymsfield ,The Journal of Clinical Endocrinology & Metabolism. 2004; 89 (2) , 632–637.

45. Effects of Calcium Supplementation on Body Weight and Blood Pressure in Normal Older Women: A Randomized Controlled Trial Ian R. Reid, Anne Horne, Barbara Mason, Ruth Ames, Usha Bava, Gregory D. Gamble The Journal of Clinical Endocrinology & Metabolism. 2005; 90 (7), 3824– 829.

Rosenblum, J.L.; Castro, V.M.; Moore, C.E.; Kaplan, L.M. Calcium and vitamin D supplementation is associated with decreased abdominal visceral adipose tissue in overweight and obese adults. Am. J. Clin. Nutr. 2012; 95, 101–108.

Winzenberg, T.; Shaw, K.; Fryer, J.; Jones, G. Calcium supplements in healthy children do not affect weight gain, height, or body composition. Obesity 2007; 15, 1789–1798.

Gomes, J.M.G.; Costa, J.D.A.; Alfenas, R.D.C.G. Dietary calcium from dairy, body composition and glycaemic control in patients with type 2 diabetes pursuing an energy restricted diet: A parallel group randomized clinical trial. Int. Dairy J. 2017; 73, 50–56.

Rautiainen, S.; Wang, L.; Lee, I.M.; Manson, J.E.; Buring, J.E.; Sesso, H.D. Dairy consumption in association with weight change and risk of becoming overweight or obese in middle-aged and older women: A prospective cohort study. Am. J. Clin. Nutr. 2016;103, 979–988.

Moreira, Pedro & Padez, Cristina & Carvalhal, Maria Isabel & Rosado Marques, Vitor. Dietary Calcium and Body Mass Index in Portuguese Children. European journal of clinical nutrition. 2005; 59, 861-7.

Arnawa, I.K., Sapanca, P.L.Y., Martini, L.K.B., Udayana, I.G.B., Suryasa, W. (2019). Food security program towards community food consumption. Journal of Advanced Research in Dynamical and Control Systems, 11(2), 1198-1210.

Nyandra, M., Kartiko, B.H., Susanto, P.C., Supriyati, A., Suryasa, W. (2018). Education and training improve quality of life and decrease depression score in elderly population. Eurasian Journal of Analytical Chemistry, 13(2), 371-377.

Published

14-06-2022

How to Cite

Jasim, A. H., Ali, B. M., & Abbas, B. G. (2022). Effect of calcium supplementation on weight loss in overweight and obese women, Baghdad, 2021. International Journal of Health Sciences, 6(S2), 14989–15002. https://doi.org/10.53730/ijhs.v6nS2.8978

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Section

Peer Review Articles