Assessment of the hemostatic activity of "hemoben" in the model of liver damage on hypocoagulation

https://doi.org/10.53730/ijhs.v6nS5.9046

Authors

  • Ismailov S.I. Republican Specialized Scientific and Practical Medical Center of Surgery named after academician V. Vakhidov
  • Babadjanov A.Kh. Republican Specialized Scientific and Practical Medical Center of Surgery named after academician V. Vakhidov
  • Khodzhiev D.Sh. Republican Specialized Scientific and Practical Medical Center of Surgery named after academician V. Vakhidov
  • Khayaliev R.Ya. Republican Specialized Scientific and Practical Medical Center of Surgery named after academician V. Vakhidov
  • Kadyrov M.Zh. Republican Specialized Scientific and Practical Medical Center of Surgery named after academician V. Vakhidov

Keywords:

hypocoagulation, hemostatic, hemoben

Abstract

In the article, the authors present the results of experimental studies on the hemostatic properties assessment of the new domestic hemostatic implant Hemoben under artificial hypocoagulation using medications on a model of a planar wound in the liver of rats. An attempt was made to stop bleeding using gauze strips and balls and a hemostatic sponge in the control group of animals. Experimental and morphological studies have convincingly proved that under drug hypocoagulation, Hemoben provides fine and stable hemostasis, which significantly exceeds the parameters of a hemostatic sponge.

Downloads

Download data is not yet available.

References

Анаев Э.Х., Княжеская Н.П. Коагулопатия при covid-19: фокус на антикоагулянтную терапию // Практическая пульмонология. 2020. №1. URL: https://cyberleninka.ru/article/n/koagulopatiya-pri-covid-19-fokus-na-antikoagulyantnuyu-terapiyu (дата обращения: 28.05.2022).

Будко Е.В., Д. А. Черникова, Л. М. Ямпольский, В. Я. Яцюк. Местные гемостатические средства и пути их совершенствования // Российский медико-биологический вестник имени академика И.П. Павлова. - 2019. -Т. 27, № 2. - С. 274-285.

Заболотских И.Б., Киров М.Ю., Афончиков В.С., и др.Периоперационное ведение пациентов, получающих длительную антитромботическую терапию. Клинические рекомендации Федерации анестезиологов-реаниматологов России. Вестник интенсивной терапии имени А.И. Салтанова. 2019;1:7–19.DOI: 10.21320/1818-474X-2019-1-7-19

Смоляр А.Н. Закрытая травма живота. Повреждения селезенки. Часть 2. // Хирургия. Журнал им. Н.И. Пирогова. - 2016. -№ 2. - С. 4-10.

Chiara O, Cimbanassi S, Bellanova G, Chiarugi M, Mingoli A, Olivero G, et al. A systematic review on the use of topical hemostats in trauma and emergency surgery. BMC Surg. 2018;18(1):68. doi:10.1186/s12893-018-0398-z.

H. Abdel-Qadir et al. The association between anticoagulation and adverse outcomes after a positive SARS-CoV-2 test among older outpatients: A population-based cohort study. ThrombosisresearchDec 2021 DOI:https://doi.org/10.1016/j.thromres.2021.12.010

Khoshmohabat H, Paydar S, Kazemi HM, Dalfardi B. Overview of agents used for emergency hemostasis. Trauma Mon. 2016;21(1):e26023.

Mehrizi TZ, Kafiabad SA, Eshghi P. Effects and treatment applications of polymeric nanoparticles on improving platelets' storage time: a review of the literature from 2010 to 2020. Blood Res. 2021 Dec 31;56(4):215-228. doi: 10.5045/br.2021.2021094.

Published

15-06-2022

How to Cite

Ismailov, S. I., Babadjanov, A. K., Khodzhiev, D. S., Khayaliev, R. Y., & Kadyrov, M. .Zh. (2022). Assessment of the hemostatic activity of "hemoben" in the model of liver damage on hypocoagulation. International Journal of Health Sciences, 6(S5), 1944–1952. https://doi.org/10.53730/ijhs.v6nS5.9046

Issue

Section

Peer Review Articles

Most read articles by the same author(s)