A novel approach towards eco-friendly green synthesis of copper nanoparticles from bunium persicum and their biomedical applications

Manju Sharma; Sushil Kumar Sharma; Manas Mathur; Manju Kumari Choudhary

doi:10.53730/ijhs.v6nS5.9155

Authors

Manju Sharma
sharmaanu374@gmail.com
School of Applied Sciences, Suresh Gyan Vihar University, Jagatpura, Jaipur, India
Sushil Kumar Sharma School of Agriculture, Suresh Gyan Vihar University, Jagatpura, Jaipur, India
Manas Mathur School of Agriculture, Suresh Gyan Vihar University, Jagatpura, Jaipur, India
Manju Kumari Choudhary Faculty of Agriculture Science, Maharishi Arvind University, Jaipur, India

Keywords:

Copper nanoparticles, Bunium persicum, Antimicrobial, Antioxidant, Antiplatelet, LDH

Abstract

Nanotechnology is getting attention profoundly rooted in current living scenario which should license a consequential, scrupulous message deeply rooted in unceasing partaking and altercation among contributors and inhabitants. Therefore, the aim of present investigation deals with synthesis and characterization of copper nanoparticles (CuNPs) by aqueous extracts of leaves of Bunium persicum. Phytochemical screening confirmed presence of carbohydrates, proteins, flavonoids and alkaloids which had major role as reducing and sustainable agent for formation of CuNPs. Further these particles were characterized by UV- Vis, FTIR, SEM, TEM, XRD and DLS. FT-IR showed presence of various function groups like alcohols, amines and hydroxyl which were engaged in reduction and capping during formation of nanoparticles. Studies by XRD, SEM and TEM confirmed that nanoparticles appear spherical and crystalline in nature when morphology was studied and their dimension ranged between 30 to 70 nm. UV spectra showed peaks at 525 nm while they were crystalline in structure. Further various pharmacological activities were performed like antimicrobial by agar well diffusion, antioxidant by various assays like Lipid peroxidation [ LPO], catalase and peroxidase and antiplatelet by Prothrombin, activated partial thromboplastin time and Lactate hydrogenase release assay (LDH).

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