Survey based on classification of PCOS using gene expression
Keywords:
polycystic ovary syndrome, phenotype, genotype, insulin resistance, antrogen based, inflammatory PCOSAbstract
Polycystic ovary syndrome (PCOS) is a complicated endocrine ailment affecting 5–10 % of girls of reproductive age. It is generally has complications such as irregular cycles, hirsutism and polycystic ovaries, collectively with a considerable incidence of insulin resistance. PCOS is taken into consideration a multifactorial ailment with numerous genetic, endocrine and environmental abnormalities. Eventhough, women who are suffered with PCOS are also have chances for cause of metabolic and cardiovascular illnesses and their associated diseases or disorders which are compared to the overall population. PCOS classification done on both phenotype and genotype, based on phenotype it is segmented into four phenotypes as A, B, C, D. This phenotype shows the association between hyperandrogenisms, structure or shape polycystic ovary and immature ovary formation. Phenotypes can be visualized through ultrasound images. Based on genotype, PCOS are categorized into three based on the hormonal factors. By analyze PCOS genetically we early diagnose the syndrome and take necessary remedial actions and also prevent from inheritance to next generations. In this paper, surveys the different genes involved in causes of PCOS and hormone factors associated with the PCOS.
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