Evaluating antimicrobial efficacy of bovine colostrum in patients suffering from periodontal disease
An invitro study
Keywords:
bovine colostrum, anti-microbial activity, plaque, periodontitisAbstract
Purpose: Bovine Colostrum is the first milk, a mammary secretion produced by all cows for their babies during the first 24–48 hours after birth. Bovine Colostrum contains immunoglobulins and lactoferrin that help in bactericidal and bacteriostatic effects against microorganisms. The purpose of this study is to evaluate the efficacy of bovine colostrum at different concentrations in patients suffering from chronic periodontitis. Methodology: Plaque and calculus samples were obtained from 15 patients aging from 30 - 60 years. The collected samples were then poured on agar plates and different strains of Gram -ve bacteria were obtained. The streak plate method was adopted. For the anti-microbial susceptibility test, a solution of Bovine Colostrum Powder was prepared in Dimethyl sulfoxide (DMSO) at various concentrations (50 µg/ml, 100 µg/ml, and 200 µg/ml). Result: A minimal zone of inhibition was seen at 50 µg/ml with a mean of 3.8. Proper inhibition zones were seen in 100 µg/ml and 200 µg/ml with means of 9.9 and 12.7 respectively. One-way ANOVA showed a statistically significant difference in the values between the groups (p<0.01). Tukey HSD Post Hoc Test showed a statistically significant difference in the values between all the pairs of groups (p<0.01).
Downloads
References
Shah NP. Effects of milk-derived bioactives: an overview. Br J Nutr 2000;84:3–10.
Macy IG. Composition of human colostrum and milk. Am J Dis Child 1949;78:589–603.
Ogra SS, Ogra PL. Immunological aspects of human colostrum and milk. J Pediatr 1978;92:550–5.
Pakkanen R, Aalto J. Growth factors and antimicrobial factors in bovine colostrum. Int Dairy J 1997;7:285–97.
Tzipori S, Roberton D, Chapman C. Remission of diarrhea due to cryptosporidiosis in an immunodeficient child treated with hyperimmune bovine colostrum. Br Med J (Clin Res Ed)1986;296:1276–7.
Pan Y, Lee A, Wan J, Coventry MJ, Michalski WP, Shiell B, et al. Antiviral properties of milk proteins and peptides. Int Dairy J 2006;16:1252–61.
Newman MG, Carranza FA, Takei H, Klokkevold PR. Carranzas clinical Periodontology. 10th ed. Elsevier health sciences; 200
Marsh PD. Dental plaque as a biofilm and microbial community implication for health and diseases. BMC Oral Health. 2006;6:S14.
Chopra I, Roberts M. Tetracycline antibiotics: mode of action,applications, molecular biology, and epidemiology of bacterialresistance. Microbiol Mol Biol Rev 2001;65:232–60.
Pakkanen R, Aalto J. Growth factors and antimicrobial factors in bovine colostrum. Int Dairy J 1997;7:285–97.
Elfstrand L, Lindmark-Månsson H, Paulsson M, Nyberg L, Åkesson B. Immunoglobulins, growth factors and growth hormone in bovine colostrum and the effects of processing. Int Dairy J 2002;12:879–87.
Kesic L. Microbial etiology of periodontal disease – mini review. Medicine and biology 2008; 15(1):1-6.
Daniluk T. Aerobic and anaerobic bacteria in subgingival and supragingival plaques of adult patients with periodontal disease. Advances in medical sciences, 2006; 51(1).
Dumitrescu AL. Etiology and pathogenesis of periodontal disease. 1 st edition, springer, 2009.
Aurer A, Plancak D. Antimicrobial treatment of periodontal diseases. Acta Stomatol Croat, 2004; 38(1).
Struff WG, Sprotte G. Bovine colostrum as a biologic in clinical medicine: A review. Int J Clini Pharma and Therap 2008; 46(5): 211-25.
Loimaranta V, Laine M, SoÈ derling E, Vasara E, Rokka S, Marnila P et. al. Effects of bovine immune and non-immune wheypreparations on the composition and pH response of human dental plaque. Eur J Oral Sci 1999; 107: 244±250. # Eur J Oral Sci, 1999
Yadav, Ramesh & Angolkar, Trupti & Kaur, Ginpreet & Buttar, Harpal. (2016). Antibacterial and Antiinflammatory Properties of Bovine Colostrum. Recent patents on endocrine, metabolic & immune drug discovery. 10. 10.2174/1872214810666160219163118.
Suryasa, I. W., Rodríguez-Gámez, M., & Koldoris, T. (2021). Get vaccinated when it is your turn and follow the local guidelines. International Journal of Health Sciences, 5(3), x-xv. https://doi.org/10.53730/ijhs.v5n3.2938
Suryasa, I.W., Sudipa, I.N., Puspani, I.A.M., Netra, I.M. (2019). Translation procedure of happy emotion of english into indonesian in kṛṣṇa text. Journal of Language Teaching and Research, 10(4), 738–746
Published
How to Cite
Issue
Section
Copyright (c) 2022 International journal of health sciences
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Articles published in the International Journal of Health Sciences (IJHS) are available under Creative Commons Attribution Non-Commercial No Derivatives Licence (CC BY-NC-ND 4.0). Authors retain copyright in their work and grant IJHS right of first publication under CC BY-NC-ND 4.0. Users have the right to read, download, copy, distribute, print, search, or link to the full texts of articles in this journal, and to use them for any other lawful purpose.
Articles published in IJHS can be copied, communicated and shared in their published form for non-commercial purposes provided full attribution is given to the author and the journal. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
This copyright notice applies to articles published in IJHS volumes 4 onwards. Please read about the copyright notices for previous volumes under Journal History.
