A prospective study to assess the comparison of hematological manifestations in alcoholics and non-alcoholics at tertiary care centre in north India
Keywords:
chronic alcoholics, alcoholism, non-alcoholics, anemiaAbstract
Background: Alcoholism is one of the most serious global public health problems. Chronic alcohol abuse results in physical illness, emotional changes and others problems in their lives and relationships. Alcohol problems can often be prevented by early identification and brief intervention. Our study was done to document the hematological changes in chronic alcohol users as early detection and treatment of hematological changes can prevent complications and reduce the morbidity and mortality. Materials & Methods: A prospective study done on 60 patients who sought treatment for alcohol use problems or its complications on an outdoor patient basis (hospital or clinic) for a period of one year (2021 to 2022) and 60 healthy non-alcoholic subjects, who visited the hospital/clinic for non-alcohol related problems and were advised for routine hematological and other relevant investigations. The hematological parameters were compared between alcohol users and non-alcoholic subjects. All data were entered and analyzed using SPSS. Chi-square tests were applied for comparing discrete variables and ANOVA was applied for comparing continuous variables and P<0.05 was considered as statistically significant. Results: Incidence of alcohol consumption is less common below the age of 25 years and above the age of 71 years, which was statistically insignificant (P=1.00).
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References
World Health Organization. The World Health Report 2002 Reducing Risks, Promoting Healthy Life. Geneva: World Health Organization; 2002. Available from: http://whqlibdoc.who.int/publications/2002/9241562072.pdf. [Last accessed on 2019 May 28].
Alcohol Atlas of India” New Delhi on 29th April 2008. www.indianalcoholpolicy.org/alcohol_atlas.html
Murray CJ, Lopez AD. Global mortality, disability, and the contribution of risk factors: Global burden of disease study. Lancet 1997;349:1436-42.
Harold S, Ballard MD. Haematological complications of alcoholism. Alcohol Health Res World 1997;21:42-52.
Stanly PC, Wakwe VC, Ejele OA. Haematological profile in chronic alcoholics consumers. Niger J Clin Pract 2003;6:84-90.
T. Oduola, O.G. Adesun, T.A. Oduola, N.R. Agbaje. Drinking patterns: biochemical and haematological findings in alcohol consumers in Ile-Ife, by Nigeria. African Journal of Biotechnology. November 2005; 4 (11):1304-08.
D M Chalmers, I Chanarin, S Macdermott, A J Levi. Sex-related differences in the haematological effects of excessive alcohol consumption. Journal of Clinical Pathology 1980;33:3-7.
Sammaiah P, Prasad R, Shekhar VC. Study of Haematological Manifestations, among Alcoholics in Tertiary Care Hospital. Int J Sci Stud 2018;6(3):135-40.
Seppä K, Sillanaukee P, Koivula T. Abnormalities of hematologic parameters in heavy drinkers and alcoholics. Alcohol Clin Exp Res 1992;16:117-21.
Das SK, Vasudevan DM. Biochemical diagnosis of alcoholism. Indian J Clin Biochem 2005;20:35-42.
Wisloff F, Boman D. Haemolytic anaemia in alcohol abuse. J Intern Med 1979;205:237-42.
Walther A, Poza U, Salamanca S, Mendieta F, Heranz S, Perez E. Hematologic aspects of alcoholics. Med Clin 1979;72:158-65.
Harold S, Ballard MD. Haematological complications of alcoholism. Alcohol Health Res World 1997;21:42-52.
Thinnahanumaih M, Puranik N, Bidare C, Kammar KF, Venkatakrishniah OK, Maitri V. Moderate allcohol intake for even a short duration has deleterious effects on hematologic profile in Indian men. Int J Med Sci Public Health 2012;1:105-8.
Chalmers DM, Rinsler MG, MacDermott S, Spicer CC, Levi AJ. Biochemical and haematological indicators of excessive alcohol consumption. Gut 1981;22:992-6.
Thoma E, Bitri S, Mucaj K, Tahiri A, Pano I. Changes of some blood count variables in correlation with the time of alcohol abuse. J Addict Res Ther 2015;6:2.
Gacouin A, Legay F, Camus C, Volatron AC, Barbarot N, Donnio PY, et al. At-risk drinkers are at higher risk to acquire a bacterial infection during an intensive care unit stay than abstinent or moderate drinkers. Crit Care Med 2008;36:1735-41.
Bagnardi V, Blangiardo M, La Vecchia C, Corrao G. Alcohol consumption and the risk of cancer: A meta-analysis. Alcohol Res Health 2001;25:263-70.
Charles AT, Everton E, Osaro E. Evaluation of haematological parameters among alcoholics in Port Harcourt Nigeria. Br J Med Health Sci 2013;5:32-44.
Das SK, Mukherjee S, Vasudevan DM, Balakrishnan V. Comparison of haematological parameters in patients with non-alcoholic fatty liver disease and alcoholic liver disease. Singapore Med J 2011;52:175-81.
J. Latvala, S. Parkkila, J. Melkko, and O. Niemelä Acetaldehyde adducts in blood and bone marrow of patients with ethanol-induced erythrocyte abnormalities. Mol Med. 2001 June; 7(6): 401-05.
Widana, I.K., Sumetri, N.W., Sutapa, I.K., Suryasa, W. (2021). Anthropometric measures for better cardiovascular and musculoskeletal health. Computer Applications in Engineering Education, 29(3), 550–561. https://doi.org/10.1002/cae.22202
Estevez, G. A., Espinosa, A. H. R., & Rodríguez, D. L. (2019). Design of intervention program for preventing of alcohol misuse in university students. International Journal of Health & Medical Sciences, 2(1), 33-38. https://doi.org/10.31295/ijhms.v2n1.86
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