Prognosis of survival among older adults with COVID-19
A systematic review and meta-analysis
Keywords:
Obesity, older adult, COVID-19, comorbidity, mortalityAbstract
Older adults hospitalized due to COVID-19 infection are at high risk of fatality. Additional fatalities such as obesity and comorbidity tend to rapidly develop into progressive clinical deterioration. Therefore, a complex survival prognosis is urgently needed to save more older adults. This study aims to systematically examine obesity and comorbidity as a prognosis of survival in older adults with COVID-19. A Systematic review was conducted using five databases; CINAHL; EMBASE; MEDLINE; PubMed, and Web of Science. Selected papers were published between 2019 and 2020 based on a computerized search. Three reviewers reviewed the quality of the included studies using the JBI (Joanna Briggs Institute) tool for cohort study. The data were compiled using the random-effect models while heterogeneity between studies was assessed using the Cochran Q and I2 statistics. A total of 40,154 data were retrieved from 8 included studies, older adults ranging from 65 to 74-year-olds, with basal metabolism index (BMI) 30-35 kg/m2, diabetes mellitus, hypertension, chronic kidney disease (CKD), and malignancy. Predictors of survival in older adults with COVID-19 include comorbidity (61.3%), obesity (7.1%), mortality (17.3%), female (6.0%), and male (8.3%).
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