Probiotics as an adjuvant treatment for recurrent aphthous ulcer
A randomized clinical trial
Keywords:
aphthous ulcers, biofilm, probiotics, tetracyclines, ulcersAbstract
Background: The most common ulcer in adults, recurrent aphthous ulcers affect roughly 25% of them. The purpose of this study was to see how beneficial probiotics are at treating it. Materials and Procedures: 160 people in total were split into two groups. Bacillus coagulans (Sporolac) and Tetracycline capsules 250 mg (Tetrastar) were given twice daily to 80 patients in Group 1 for 7 days. In Group 2, 80 patients received just Tetracycline capsules 250 mg (Tetrastar) twice a day for 7 days. At the beginning, fourth, and seventh days of the ulcer, discomfort, size, and average duration were recorded. In order to compare the parameters between the two groups, the Mann-Whitney U test was performed. Results: Over the course of just four days, all of the metrics for the Probiotic group dropped substantially. Conclusion: RAS can be treated and managed with probiotics as adjuvant therapy.
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