Patterns of antimicrobial prescribing, utilization, and cost of in patients attending a tertiary care hospital's general medicine ward

A retrospective study

https://doi.org/10.53730/ijhs.v6nS5.9699

Authors

  • Kanaka Durga Devi. Nelluri KVSR Siddhartha College of Pharmaceutical Sciences, Vijayawada, Andhra Pradesh, India
  • Shaik Asha Begum Nirmala College of Pharmacy, Atmakur, Mangalagiri, Andhra Pradesh, India
  • Ponnaluri. Lalitha KVSR Siddhartha College of Pharmaceutical Sciences, Vijayawada, Andhra Pradesh, India
  • Polimetla Haripriya KVSR Siddhartha College of Pharmaceutical Sciences, Vijayawada, Andhra Pradesh, India
  • Motupalli Sankeerth Kumar KVSR Siddhartha College of Pharmaceutical Sciences, Vijayawada, Andhra Pradesh, India
  • Seelam Victor John Wilson KVSR Siddhartha College of Pharmaceutical Sciences, Vijayawada, Andhra Pradesh, India

Keywords:

STG-standard treatment guidelines, AMR- Anti Microbial Resistance, Stewardship Programs, Antibiotics

Abstract

Background: Antibiotic overuse is of great public health concern.Multiple studies performed globally have demonstrated a strong association between antibiotic use and antibiotic resistance (AMR), at both individual and community levels and they also shown that Antimicrobials are most commonly prescribed medications in acute care settings with 80% of its usedeemed inappropriate. Objectives: The primary aim of this study was to determine the possible impact of appropriate prescribing of antibiotics in General medicine ward of tertiary health centre on treatment outcomes and costs related to treatment. Methodology: This retrospective study looked at antimicrobial prescribing data in patients admitted to general medicine.Patients data was retrieved from Medical record section and the records of discharged patients were reviewed. The demographic data, disease related data and utilization of antibiotics were noted in specially designed proforma and analyzed. The documented data evaluated for use, safety outcomes and cost for the treatment associated with the use of antibiotics. Results: Female patients 60.2 % (n=759)aremore hospitalized when compared to males, Average length of stay in hospital was 8 days. Majority of hospitalized patients had HTN & DM as primary comorbidities. The widely prescribed antibiotics among all classes as prophylaxis were third generationcephalosporins in parenteral form.

Downloads

Download data is not yet available.

References

Ozkurt Z, Erol S, Kadanali A, Ertek M, Ozden K, Tasyaran MA. Change in antibiotic use, cost and consumption after an antibiotic restriction policy applied by infectious disease specialist. Jpn J Infect Dis. 2005; 58: 338-43.

Sharma M, Eriksson B, Marrone G, Dhaneria SP, Lundborg CS. Antibiotic prescribing in two private sector hospitals; one teaching and one non-teaching: A cross-sectional study in Ujjain, India.BMC Infectious Disease 2012;12:155.

Kanakadurgadevi.N,Lakshmisuneetha G,Nikhitha P. Algorithms for detecting,assessing,reporting and avoidance of adverse drug reactions. Int.J.Pharm.Sci.Rev.Res 2012 ; 17(2): 93-96.

Hallsworth M et al., Provision of social norm feedback to high prescribers of antibiotics in general practice: a pragmatic national randomised controlled trial. Lancet. 2016 Apr 23;387(10029):1743-52.

Al Shimemeri A, Al Ghadeer H, Memish Z. Antibiotic utilization pattern in a general medical ward of a tertiary medical center in Saudi Arabia. Avicenna J Med 2011 Jul;1(1):8–11.

N.K. Durga Devi, Anusha J., Rajesh A., Varsha CH., Harshavardhan G., Giridhar J. and G. Devala Rao. A Study On Prescribing Patterns Of Antibiotics And Its Rationality In Hospitalized Patients Of A Tertiary care Teaching Hospital. The Indian Pharmacist, Vol. XIV (1), 2016: 53-60.

Kollef MH, Sherman G, Ward S, Fraser VJ. Inadequate antimicrobial treatment of infections: a risk factor for hospital mortality among critically ill patients. Chest 1999;115:462–74.

Suryasa, I. W., Rodríguez-Gámez, M., & Koldoris, T. (2021). Health and treatment of diabetes mellitus. International Journal of Health Sciences, 5(1), i-v. https://doi.org/10.53730/ijhs.v5n1.2864

C. den Engelsen et al., Infectious diseases and the use of antibiotics in outpatients at the emergency department of the University Hospital of Leo´n, Nicaragua. International Journal of Infectious Diseases (2009) 13, 349—354.

Hicks La et al., US outpatient antibiotic prescribing variation according to geography, patient population, and provider specialty in 2011. lin Infect Dis. 2015 May 1;60(9):1308-16.

Widyaningrum , I. ., Wibisono, N. ., & Kusumawati, A. H. . (2020). Effect of extraction method on antimicrobial activity against staphylococcus aureus of tapak liman (elephantopus scaber l.) leaves. International Journal of Health & Medical Sciences, 3(1), 105-110. https://doi.org/10.31295/ijhms.v3n1.181

Little P, Stuart B, Hobbs FD, et al. Predictors of suppurative complications for acute sore throat in primary care: prospective clinical cohort study. BMJ 2013; 347: f6867.

Published

25-06-2022

How to Cite

Nelluri, K. D. D., Begum, S. A., Lalitha, P., Haripriya, P., Kumar, M. S., & Wilson, S. V. J. (2022). Patterns of antimicrobial prescribing, utilization, and cost of in patients attending a tertiary care hospital’s general medicine ward: A retrospective study. International Journal of Health Sciences, 6(S5), 4995–5006. https://doi.org/10.53730/ijhs.v6nS5.9699

Issue

Section

Peer Review Articles

Most read articles by the same author(s)