Assessment of effect of anti-platelet therapy on minor surgical procedures

Tabish Uzair Saify; Abhay Partap Singh; Ramandeep Singh Brar; Mandeep Kaur; Harkanwal Preet Singh

doi:10.53730/ijhs.v6nS5.9834

Authors

Tabish Uzair Saify Lecturer, Dasmesh Institute of Research and Dental Sciences, Faridkot, Punjab, India
Abhay Partap Singh BDS student, Dasmesh Institute of Research and Dental Sciences, Faridkot, Punjab, India
Ramandeep Singh Brar Professor, Department of Oral and Maxillofacial Surgery, Dasmesh Institute of Research and Dental Sciences, Faridkot, Punjab, India
Mandeep Kaur Associate Professor, Department of Oral Medicine and Radiology, Dasmesh Institute of Research and Dental Sciences, Faridkot, Punjab, India
Harkanwal Preet Singh
hkps0320@gmail.com
Professor, Department of Oral and Maxillofacial Pathology, Dasmesh Institute of Research and Dental Sciences, Faridkot, Punjab, India

Keywords:

Antiplatelet therapy, Aspirin, Minor surgical procedures

Abstract

Background: Antiplatelet therapy is to treat thromboembolic disorders, but it causes hemorrhages. Aspirin is the drug in regular practice. The present study was conducted to assess the effect of anti- platelet therapy on minor surgical procedures. Materials & Methods: 80 patients selected for mandibular third molar extraction of both genders were randomly divided into 2 groups of 40 each. In Group I, patients on antiplatelets drugs (75 mg of aspirin/ 75 mg clopidogrel) were enrolled and in group II, patients who discontinued the drug before 5 days of extraction of mandibular third molar were enrolled. Bleeding was observed after 1 and 24 hours. Results: Group I had 24 males and 16 females and group II had 14 males and 26 females. The mean bleeding time in group I was 75.21 seconds and in group II was 75.14 seconds. The mean duration of surgery in group I was 54.2 months and in group II was 52.1 months. After 1 hour, no bleeding was seen in 38 in group I and 39 in group II and ooze in 2 in group I and 1 in group II.

Downloads

Download data is not yet available.

References

Gimbel ME, Minderhoud SCS, Ten Berg JM. A practical guide on how to handle patients with bleeding events while on oral antithrombotic treatment. Neth Heart J. 2018 Jun;26(6):341–351.

Lu SY, Lin LH, Hsue SS. Management of dental extractions in patients on warfarin and antiplatelet therapy. J Formos Med Assoc. 2018;117:979–86.

Cañigral A, Silvestre FJ, Cañigral G, Alós M, Garcia-Herraiz A, Plaza A. Evaluation of bleeding risk and measurement methods in dental patients. Med Oral Patol Oral Cir Bucal. 2010;15:e863–8.

Lillis T, Didagelos M, Lillis L, Theodoridis C, Karvounis H, Ziakas A. Impact of post-exodontia bleeding in cardiovascular patients: A new classification proposal. Open Cardiovasc Med J. 2017;11:102–10.

Lockhart PB, Gibson J, Pond SH, Leitch J. Dental management considerations for the patient with an acquired coagulopathy Part 1: Coagulopathies from systemic disease. Br Dent J. 2003;195:439–45.

Cardona-Tortajada F, Sainz-Gómez E, Figuerido-Garmendia J, de Robles-Adsuar AL, Morte-Casabó A, Giner-Muñoz F, et al. Dental extractions in patients on antiplatelet therapy. A study conducted by the Oral Health Department of the Navarre Health Service (Spain) Med Oral Patol Oral Cir Bucal. 2009;14:e588–92.

Suryasa, I. W., Rodríguez-Gámez, M., & Koldoris, T. (2021). Get vaccinated when it is your turn and follow the local guidelines. International Journal of Health Sciences, 5(3), x-xv. https://doi.org/10.53730/ijhs.v5n3.2938

Lillis T, Ziakas A, Koskinas K, Tsirlis A, Giannoglou G. Safety of dental extractions during uninterrupted single or dual antiplatelet treatment. Am J Cardiol. 2011;108:964–7.

Shah A, Shah ST, Shah I, Rehman Z. Post extraction bleeding associated with long term maintenance dose of aspirin 75–150 mg. Pakistan Oral Dent J. 2012;32:199–202.

Malik AH, Majeed S. Effect of antiplatelet therapy on minor dental procedures. National Journal of Maxillofacial Surgery. 2020 Jan;11(1):64.

Giri, M. K. W. (2019). Immunological side in overtraining exercise. International Journal of Health & Medical Sciences, 2(1), 1-6. https://doi.org/10.31295/ijhms.v2n1.52

Zabojszcz M, Malinowski KP, Janion-Sadowska A, Lillis T, Ziakas A, Sławska A, Janion M, Siudak Z. Safety of dental extractions in patients on dual antiplatelet therapy–A meta-analysis. Advances in Interventional Cardiology/Postępy w Kardiologii Interwencyjnej. 2019 Apr 4;15(1):68-73.

Kumar A, Rao A, Nimkar A, Mahajani M, Suvvari RK, Bhanot R. Evaluating the need of continuing the antiplatelet drug therapy in patients undergoing minor oral surgical procedures. Journal of Pharmacy and Bioallied Sciences. 2021 Jun 1;13(5):80.