Synthesis, characterization of new 3-Chloro-Azetidine-2-One and 1, 3-thiazinan-4-one derivatives from di imines
Keywords:
Schiff's bases, (benzylideneamino)-3-chloro-4-phenylazetidin-2-one, 3-(3-chloro-2-oxo-4-phenylazetidin-1-yl)-2-phenyl-1,3-thiazinan-4-oneAbstract
The study Included synthesis of some new Derivatives of (benzylideneamino)-3-chloro-4-phenylazetidin-2-one and 3-(3-chloro-2-oxo-4-phenylazetidin-1-yl)-2-phenyl-1,3-thiazinan-4-one by tow steps; The first include amino group of the di amino was condensed with different aromatic aldehydes in the presence of absolute ethanol to give new Schiff bases derivatives [1– 3] respectively. The second step , the resulting imines derivatives [1 – 3] were reacted with chloro acetyl chloride in presence of triethylamine in dry benzene by per cyclic reaction to give novel 3-(3-chloro-2-oxo-4-phenylazetidin-1-yl) derivatives (A1-A3 ) and reacted with 3- mercapto propanoic acid with (Schiff-base) in dry benzene to give1,3-thiazinan-4-one derivative's(Z1-Z9) The composites prepared were described by melting point .Most of these derivatives were confirmed by "FT-IR, 1HNMR spectra.
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