A review on phytochemical and pharmacological, medicinal properties of holy basil (Ocimum sanctum L.)

https://doi.org/10.53730/ijhs.v6nS4.10165

Authors

  • Krishnendu Sen Research Scholar, Dev Bhoomi Institute of Pharmacy & Research, Dehradun (Uttarakhand) India
  • Mohit Goyal Professor, School of Pharmacy & Research, Dev Bhoomi Uttarakhand University, Dehradun (Uttarakhand) India
  • Sayantan Mukopadayay Associate Dean, School of Pharmacy and Research, Dev Bhoomi Uttarakhand University, Dehradun (Uttarakhand), pin code-248007

Keywords:

ocimum sanctum, lamiaceae, tulsi, anti-oxidant, holy-basil, anti-inflamation, tenuiflorum

Abstract

Ocimum sanctum Linn. commonly referred to as Holy Basil or Tulsi is an Ayurvedic herb of Southeast Asia with extended records of traditional use. The culinary, medicinal, and industrial importance of this plant brought about to explore its chemical and pharmacological residences. right here, we offer a comprehensive assessment of medical findings of O. sanctum chemical materials and their related anticancer, antioxidant, antistress, γ-irradiation protection, antidiabetic and antileishmanicidal sports. more than 60 chemicals have been said from O. sanctum, inclusive of phenolics, flavonoids, phenylpropanoids, terpenoids, fatty acid derivatives, crucial oil, constant oil, and steroids. The pharmacological sports of O. sanctum compounds replicate their medicinal significance and inside the standardization of medicinal merchandise. This compilation could be useful in the improvement of recent active principles and nutraceuticals within the vicinity of drug resistance and rising persistent sickness vectors.Tulsi (Ocimum sanctum) member of the family (Lamiaceae) is the mostgood-sized medicinal flower cited in Ayurvedic creative writing for itsmedicinal and non-secular houses. the foundation, seeds, and leaves are majorly used due toits therapeutically housed. 

Downloads

Download data is not yet available.

References

Adhvaryu MR, Reddy N, Vakharia BC (2008) Prevention of hepatotoxicity due to anti tuberculosis treatment: a novel integrative approach. World J Gastroenterol 14: 4753-4762.

Ahmed, M., R.N. Ahamed, R.H. Aladakatti and M.G. Ghosesawar, 2002. Reversible anti-fertility effect of benzene extract of Ocimum sanctum leaves on sperm parameters and fructose content in rats. J. Basic Clin. Physiol. Pharmacol., 13: 51-59.

Anbarasu K, Vijayalakshmi G. Improved shelf life of protein-rich tofu using Ocimum Sanctum(Tulsi) extracts to benefit Indian rural population. J Food Sci. 2007; 72(8):M300-M305.

Anbarasu, K. and G. Vijayalakshmi, 2007. Improved shelf life of protein-rich tofu using Ocimum sanctum (Tulsi) extracts to benefit Indian rural population. J. Food Sci., 72: M300-M305.

Das S.K., Vasudevan D.M. (2006). Tulsi: The Indian holy power plant. Natural Product Radiance,5:279-83.

Diniari, N. K. S., & Aryani, L. N. A. (2022). Characteristics and pharmacological treatment options of delirium patients treated at Sanglah Central General Hospital . International Journal of Health & Medical Sciences, 5(1), 37-43. https://doi.org/10.21744/ijhms.v5n1.1835

Farivar TN, Fard AHM, Zahedani SS, Naderi M, Moud BS. Anti tuberculosis effect of Ocimum sanctum extracts in in-vitro and macrophage culture. J Medicinal Sci. 2006;6:34851.

Gupta S.K., Prakash J., Srivastava S.(2002). Validation of traditional claim of Tulsi, Ocimum sanctum Linn. as a medicinal plant. Indian J Exp Biol, 40: 765-773.

Khan A, Ahmad A, Akhtar F, Yousuf S, Xess I, Khan LA et al. Ocimum sanctum essential oil and its active principles exert their antifungal activity by disrupting ergo sterol biosynthesis and membrane integrity.ResMicrobiol. 2010; 161:816-823.

Marja PK, Anu IH, Heikki JV, Jussi-Pekka R, Kalevi P, Tytti SK et al. Antioxidant activity of plant extracts containing phenolic compounds. J Agric Food Chem. 1999;47(10):395462.

Mishra P, Mishra S. Study of antibacterial activity of Ocimum sanctum extract against gram positive and gram negative bacteria. Am J Food Technol. 2011;6:336-41.

Mondal S, Bijay R, Miranda RB, Sushil CM. The Science behind Sacredness of Tulsi (Ocimum sanctumL.). Ind J of Physiol Pharmacol. 2009; 53:291-306.

Naquvi JK, Dohare LS, Shuaib M, Ahmad IM. Chemical Composition of Voatile Oil of Ocimum SanctumLinn. Int J of Biomed and Adv Res. 2012; 3:129-131.

Prashar R, Kumar A, Hewer A, Cole KI, Davis W, et al. (1998) Inhibition by an extract of Ocimum sanctum of DNA-binding activity of 7,12-dimethylbenz[a] anthracene in rat hepatocytes in vitro. Cancer Lett 128:155-160.

Rahman MS, Khan MMH, Jamal MAHM. Antibacterial. Anti-bactirial evaluation and minimum inhibitory concentration analysis of Oxalis corniculata and Ocimum sanctum against bacterial pathogens. Biotechonology. 2010;9:533-6.

S. Singh et al. Effect of Ocimum sanctum fixed oil on blood pressure, blood clotting time and pentobarbitone-induced sleeping time J. Ethnopharmacology. (2001)

S. Singh et al.Evaluation of the gastric antiulcer activity of fixed oil of Ocimumsanctum (Holy basil) J. Ethnopharmacol. (1999).

Singh N., Hoette Y., Miller R. (2010). Tulsi: The Mother Medicine of Nature. 2nd ed. Lucknow: International Institute of Herbal Medicine, 28–47.

Sridevi, G., P. Gopkumar, S. Ashok and C.S. Shastry, 2009. Pharmacological basis for antianaphylactic, antihistaminic and mast cell stabilization activity of Ocimum sanctum. Internet J. Pharmacol., Vol. 7

Suryasa, I. W., Rodríguez-Gámez, M., & Koldoris, T. (2021). Health and treatment of diabetes mellitus. International Journal of Health Sciences, 5(1), i-v. https://doi.org/10.53730/ijhs.v5n1.2864

Vani RS, Cheng SF, Chuah CH. Comparative Study of Volatile Compounds from Genus Ocimum. Am J of Appl. Sci. 2009; 6:523-528.

Published

02-07-2022

How to Cite

Sen, K., Goyal, M., & Mukopadayay, S. (2022). A review on phytochemical and pharmacological, medicinal properties of holy basil (Ocimum sanctum L.). International Journal of Health Sciences, 6(S4), 7276–7286. https://doi.org/10.53730/ijhs.v6nS4.10165

Issue

Section

Peer Review Articles

Most read articles by the same author(s)

1 2 > >>