Understanding the significance and outcomes of clinical pharmacology of ibuprofen
Keywords:
Clinical Pharmacology, Ibuprofen, food-drugAbstract
In patients with moderate or actual suffering following third molar extraction, a clinical primer separating ibuprofen, 400, 600, and 800 mg, from aluminum ibuprofen, 400 mg, and counterfeit medication was coordinated. Ibuprofen serum levels and torture power assessments were taken as usual. Ibuprofen was discovered as the first of the Prop ionic destructive subordinates in 1969. It is a well-known over-the-counter pain reliever and antipyretic for both adults and children. The Unrestricted Adverse Medication Response UK reporting framework ranks ibuprofen as the safest traditional NSAID. This article summarizes the actual pharmacological effects, therapeutic uses and side effects of ibuprofen, drug communication, and food-drug collaboration that have been considered over the last decade.
Downloads
References
Tripathi KD. Non steroidal anti inflammatory drugs and anti pyretic analgesics In: Essentials of medical pharmacology. 5th edn., Jaypee Brothers, New Delhi, 2003. p. 176.
Abrahm P. KI KD. Nitro-argenine methyl ester, a non selective inhibitor of nitric oxide synthase reduces ibuprofen-induced gastric mucosal injury in the rat. Dig Dis 2005;50(9):1632-1640 .10.1007/s10620-005-2908-y
Bradbury F. How important is the role of the physician in the correct use of a drug? An observational cohort study in general practice. Int J Clin Prat 2004; (144):27-32.
Chavez ML, DeKorte CJ. Valdecoxib: a review. Clin Ther 2003. Mar;25(3):817-851. 10.1016/S0149-2918(03)80110-8
Wahbi AA, Hassan E, Hamdy D, Khamis E, Barary M. Spectrophotometric methods for the determination of Ibuprofen in tablets. Pak J Pharm Sci 2005. Oct;18(4):1-6
Halford GM, Lordkipanidzé M, Watson SP. 50th anniversary of the discovery of ibuprofen: an interview with Dr Stewart Adams. Platelets. 2012;23(6):415-22.
Akgul O, Di Cesare Mannelli L, Vullo D, Angeli A, Ghelardini C, Bartolucci G, Alfawaz Altamimi AS, Scozzafava A, Supuran CT, Carta F. Discovery of Novel Nonsteroidal Anti-Inflammatory Drugs and Carbonic Anhydrase Inhibitors Hybrids (NSAIDs-CAIs) for the Management of Rheumatoid Arthritis. J Med Chem. 2018 Jun 14;61(11):4961-4977.
González-Barnadas A, Camps-Font O, Martín-Fatás P, Figueiredo R, Gay-Escoda C, Valmaseda-Castellón E. Efficacy and safety of selective COX-2 inhibitors for pain management after third molar removal: a meta-analysis of randomized clinical trials. Clin Oral Investig. 2020 Jan;24(1):79-96.
Ekinci M, Ciftci B, Celik EC, Köse EA, Karakaya MA, Ozdenkaya Y. A Randomized, Placebo-Controlled, Double-Blind Study that Evaluates Efficacy of Intravenous Ibuprofen and Acetaminophen for Postoperative Pain Treatment Following Laparoscopic Cholecystectomy Surgery. J Gastrointest Surg. 2020 Apr;24(4):780-785.
Narayan K, Cooper S, Morphet J, Innes K. Effectiveness of paracetamol versus ibuprofen administration in febrile children: A systematic literature review. J Paediatr Child Health. 2017 Aug;53(8):800-807.
Halford GM,Lordkipanidzé M,Watson SP, 50th anniversary of the discovery of ibuprofen: an interview with Dr Stewart Adams. Platelets. 2012;
Akgul O,Di Cesare Mannelli L,Vullo D,Angeli A,Ghelardini C,Bartolucci G,Alfawaz Altamimi AS,Scozzafava A,Supuran CT,Carta F, Discovery of Novel Nonsteroidal Anti-Inflammatory Drugs and Carbonic Anhydrase Inhibitors Hybrids (NSAIDs-CAIs) for the Management of Rheumatoid Arthritis. Journal of medicinal chemistry. 2018 Jun 14;
González-Barnadas A,Camps-Font O,Martín-Fatás P,Figueiredo R,Gay-Escoda C,Valmaseda-Castellón E, Efficacy and safety of selective COX-2 inhibitors for pain management after third molar removal: a meta-analysis of randomized clinical trials. Clinical oral investigations. 2019 Apr 23;
Suryasa, I. W., Rodríguez-Gámez, M., & Koldoris, T. (2021). The COVID-19 pandemic. International Journal of Health Sciences, 5(2), vi-ix. https://doi.org/10.53730/ijhs.v5n2.2937
Gaibullaeva, N. N. (2021). The role of clinical examination early diagnosis of glaucoma. International Journal of Health & Medical Sciences, 4(3), 333-337. https://doi.org/10.31295/ijhms.v4n3.1745
Ekinci M,Ciftci B,Celik EC,Köse EA,Karakaya MA,Ozdenkaya Y, A Randomized, Placebo-Controlled, Double-Blind Study that Evaluates Efficacy of Intravenous Ibuprofen and Acetaminophen for Postoperative Pain Treatment Following Laparoscopic Cholecystectomy Surgery. Journal of gastrointestinal surgery: official journal of the Society for Surgery of the Alimentary Tract. 2019 Apr 22;
Narayan K,Cooper S,Morphet J,Innes K, Effectiveness of paracetamol versus ibuprofen administration in febrile children: A systematic literature review. Journal of paediatrics and child health. 2017 Aug;
Published
How to Cite
Issue
Section
Copyright (c) 2022 International journal of health sciences
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Articles published in the International Journal of Health Sciences (IJHS) are available under Creative Commons Attribution Non-Commercial No Derivatives Licence (CC BY-NC-ND 4.0). Authors retain copyright in their work and grant IJHS right of first publication under CC BY-NC-ND 4.0. Users have the right to read, download, copy, distribute, print, search, or link to the full texts of articles in this journal, and to use them for any other lawful purpose.
Articles published in IJHS can be copied, communicated and shared in their published form for non-commercial purposes provided full attribution is given to the author and the journal. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
This copyright notice applies to articles published in IJHS volumes 4 onwards. Please read about the copyright notices for previous volumes under Journal History.
