Evaluation of antibacterial activity of different Moringa oleifera leaf extract on Streptococcus mutans: An in-vitro antimicrobial study

Walid A. M. Fouad; Ehab A. Fouad

doi:10.53730/ijhs.v6nS5.10385

Authors

Walid A. M. Fouad Department of Preventive Dentistry, Faculty of Dentistry, Umm Al-Qura University (UQU), Makkah, Saudi Arabia & Department of Pediatric Dentistry, Faculty of Dentistry, Cairo University, Egypt
Ehab A. Fouad Department of Microbiology and Immunology, National Research Centre, 33 Bohouth St., Dokki, Cairo, Egypt

Keywords:

dental caries, Moringa oleifera, Streptococcus mutans

Abstract

Dental caries, which has a complex etiology brought on by several facultative anaerobes, is a well-known serious oral health issue in the majority of developing countries. The primary pathogen linked to this illness is Streptococcus mutans. S. mutans species that are resistant to numerous commercial antibiotics have been found in dental caries patients. Multi-drug resistance (MDR) is a natural occurrence that poses a significant global hazard to human health. While there are several therapeutic options for treating or preventing dental decay, the worldwide burden of MDR-related diseases is continually growing. In order to evaluate the effectiveness of different Moringa oleifera leaf extract as a solvent to control S. mutans infection the current study was created. S. mutans was isolated and identified, then used the disc diffusion method to assess the isolates' susceptibility to antibiotics as well as different extracts. The results of a one-way ANOVA exposed significant (P< 0.001) differences between the various extract solutions and S. mutans. The highest level of efficacy among the three extract was ethanol extract on another hands the cold distal water extract was the lowest efficacy against S. mutans. M. oleifera solution with ethanol extract is more effective than the other extract types.

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