Pharmacological screening of scutia myrtina for antipyretic activity

https://doi.org/10.53730/ijhs.v6nS6.10588

Authors

  • Pravin Dhone Professor & Head, Department of Pharmacology, RSDKS GMC, Ambikapur
  • Kavita Associate professor Government medical college Mahasamund
  • Tanaji Shende Associate professor, Department of Pharmacology, NKPSIMS, Nagpur
  • P. N. Khandelwal Professor Of Pharmacology, MGM Medical College, Kamothe, Navi Mumbai Corresponding Author

Keywords:

Ayurvedic medicines, Pyrexia, Antipyretic, Scutia myrtina

Abstract

Herbal medicines have been main source of primary healthcare in all over the world. From ancient times, plants have been catering as rich source of effective and safe medicines. About 80 % of world populations are still dependent on traditional medicines. The present investigation it may be concluded that the hydroalcoholic extract of leaves of Scutia myrtina has antipyretic activity. All these biological activities may be said to be a promising finding brought out by the present study. These contributions can be used as parameters for the authentication of plant as well as for developing newer drugs based on their activity. In this study no attempt was made to ascertain the mechanism of the observed antipyretic activity. However, it can be suggested that it may be acting through either the peripheral or central mechanism numerated above. It is also possible that both the mechanisms may be involved. Further, study regarding isolation and characterization of active principle responsible for antipyretic activity are under planning in our laboratory.

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References

Ballabh B and Chaurasia OP. Traditional medicinal plants of cold desert Ladakh--used in treatment of cold, cough and fever. J Ethnopharmacol, 2007, 112: 341.

Chhabra SC, Mahunnah RLA, Mshiu EN. (1991) Plants used in Traditional Medicine in Eastern Tanzania. V. Angiosperms (Passifloraceae to Sapindaceae). J. Ethnopharmacol. 7, 143-157.

Cuman, RKN, Bersani-Amadio CA, Fortes ZB. (2001) Influence of type 2 diabetes on the inflammatory response in rats. Inflam. Res. 50, 460-465. Dunne MW. Pathophysiology: Concepta of altered Health States with Contributors, In: Porth CM, Lippincott eds. Philadlphia, pp. 165-176. Dhar ML, Dhar MM, Dhawan BN, Mehrotra BN, Ray C. (1968) Screening of Indian plants for biological activity Indian J. Exp. Biol. 6, 232-247. Hedberg I,

El SN and Karakava S. Radical scavenging and ironchelating activities of some greens used as traditional dishes in Mediterranean diet. Int J Food Sci Nutr, 2004, 55: 67.

El-shenawy SM, Abdel-salam OM, Baiuomy AR, El-batran S, Arbid MS (2002) Studies on the antiinflammatory and anti-nociceptive effects of melatonin in the rat. J. Pharmacol. 46, 235-243.

Gakunju DMN, Mberu EK, Dossaji SF, Gray AI, Waigh RD, Waterman PG, Watkins WM. (1995) Potent antimalarial activity of the Alkaloid Nitidine, Isolated from a Kenyan herbal remedy. Antimicrob. Agent’s Chimother. 39, 2606-2609.

Hedberg O, Mashigeni KE, Mshiu, EN, Samuelsson G, (1983) Inventory of plants usedin traditional medicine in Tanzania, part III Plants the families Papilionaceae-Vitaceae. J. Ethnopharmacol. 9, 237-260.

Kaij-A-Kamb M, Amoros M, Girre L. (1992) Search for new antiviral agents of plant origin. Pharma. Acta. Helv. 67, 130-147

Mufidah, N., Suhron, M., & Wahyudi, R. (2021). Analysis of post-stroke anxiety (PSA) factors during the COVID-19 pandemic in Indonesia. International Journal of Health & Medical Sciences, 5(1), 1-6. https://doi.org/10.21744/ijhms.v5n1.1807

Recio MC, Giner GM, Manez S, Ros JL. (1995) Structural requirements for the anti-inflammatory activity of natural terpenoids. Planta. Med. 6, 182-185.

Samy PR, Iushparaj PN, Gopalakrishnakone PA. Compilation of bioactive compounds from Ayurveda Bioinformation, 2008.

Subhose V, Narian A. Basic principles of pharmaceutical science in Ayurvĕda. Bull Indian Inst Hist Med Hyderbad, 2005, 35: 83.

Suleyman H, Demirezer LO, Kuruuzum A, Banoglu ZN, Gocer F, Ozbakir G, Gepdireman A. (1991) Anti-inflammatory effect of the aqueous extract from Rumex patientia L. roots, J. Ethnopharmacol. 65, 141-148.

Suryasa, I. W., Rodríguez-Gámez, M., & Koldoris, T. (2021). Get vaccinated when it is your turn and follow the local guidelines. International Journal of Health Sciences, 5(3), x-xv. https://doi.org/10.53730/ijhs.v5n3.2938

Widana, I.K., Sumetri, N.W., Sutapa, I.K., Suryasa, W. (2021). Anthropometric measures for better cardiovascular and musculoskeletal health. Computer Applications in Engineering Education, 29(3), 550–561. https://doi.org/10.1002/cae.22202

Winter CA, Poster CC. (1957) Effect of alteration in side chain up on anti-inflammatory and liver glycogen activities in hydrocortisone ester. J. Am. Pharmacol. Soc. 46, 515-519.

Winter CA, Risely EA, Nuss GW. (1962) Carrageenan induced oedema in hind paw of the rat as assays for anti-inflammatory drugs. Exp. Biol. Med. 111, 544-547.

World Health Organization: Quality control methods for medicinal plant materials. Published by WHO, Geneva, 1998.

Published

12-07-2022

How to Cite

Dhone, P., Kavita, K., Shende , T., & Khandelwal, P. N. (2022). Pharmacological screening of scutia myrtina for antipyretic activity . International Journal of Health Sciences, 6(S6), 1222–1229. https://doi.org/10.53730/ijhs.v6nS6.10588

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Peer Review Articles