Spirometric evaluation of respiratory complications of new pulmonary TB patients after completion of antitubercular treatment
Keywords:
anti tubercular treatment, spirometry, post tubercular airway diseaseAbstract
Introduction-Tuberculosis is a major public health problem of all times globally. TB Infects about one fourth of global population. To evaluate and assess the detailed information about the prevalence of abnormal lung function on spirometry of such patients this study was conducted. Material and Methods- Between Nov2017 to Oct2019, we prospectively evaluated all the patients who were diagnosed as case of pulmonary TB after completing full course of ATT at tertiary care hospital RMCH Bareilly. Results-Out of 210 patients (122)58.09% were males and (88)41.9% were females. Majority of patients lies within age group of (20-60 yrs) 163(77.6%).Smoking history were present in 70(33.3%) of patients. About 84(40%) of patients have BMI <18.5 and 97(46.2%) patients had BMI between 18.5- 24.9 and rest patients had BMI >25. After completing ATT the most common symptoms that patient had SOB 201(95.7%) followed by Dry Cough 121(57.6%) and Expectoration 38(18%). Out of 210 patients 172(81.9%) of patients have abnormal lung function. Conclusion- We found that out of all the symptomatic post TB patients, 172(81.9%) had abnormal lung function and among them majority of patients had Restrictive pattern i.e. 118(56.2%), 27(12.8%) had mixed pattern and 7(3.3%) had obstructive pattern on spirometry.
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Amaral AF, Coton S, Kato B, Tan WC, Studnicka M, Janson C, Gislason T, Mannino D, Bateman ED, Buist S, Burney PG. Tuberculosis associates with both airflow obstruction and low lung function: BOLD results. European Respiratory Journal. 2015 Oct 1;46(4):1104-12.
Choi CJ, Choi WS, Lee SY, Kim KS. The definition of past tuberculosis affects the magnitude of association between pulmonary tuberculosis and respiratory dysfunction: Korea National Health and Nutrition Examination Survey, 2008–2012. Journal of Korean Medical Science. 2017 May 1;32(5):789-95
Gali JH, Varma HV, Badam AK. Study of the post tuberculosis lung diseases and the impact of various patient and disease related factors on its occurrence IJAM. 2019 Jul; p.1241-1246.
Hanekom S, Pharaoh H, Irusen E, Daniels KJ. Post-tuberculosis health-related quality of life, lung function and exercise capacity in a cured pulmonary tuberculosis population in the Breede Valley District, South Africa. South African Journal of Physiotherapy. 2019 Jan 1;75(1):1-8.
Nyagura, Tatenda M (2016). Prevalence of post-tuberculosis airflow obstruction in patients who have completed pulmonary tuberculosis treatment at two infectious disease hospitals in Zimbabwe.
Patil ML, Anderson R, Van Rensburg CE, Page-Shipp L, Blott JA, Fresen JL, Feldman C. Influence of antimicrobial chemotherapy on spirometric parameters and pro-inflammatory indices in severe pulmonary tuberculosis. European Respiratory Journal. 1998 Aug 1;12(2):35
Qaseem A, Wilt TJ, Weinberger SE, Hanania NA, Criner G, van der Molen T, Marciniuk DD, Denberg T, Schünemann H, Wedzicha W, MacDonald R. Diagnosis and management of stable chronic obstructive pulmonary disease: a clinical practice guideline update from the American College of Physicians, American College of Chest Physicians, American Thoracic Society, and European Respiratory Society. Annals of internal medicine. 2011 Aug 2;155(3):179-91.
Radovic M, Ristic L, Ciric Z, Dinic-Radovic V, Stankovic I, Pejcic T, Rancic M, Bogdanovic D. Changes in respiratory function impairment following the treatment of severe pulmonary tuberculosis–limitations for the underlying COPD detection. International Journal of Chronic Obstructive Pulmonary Disease. 2016;11:1307
Rakhmonov, O. M., Shadmanov, A. K., & Juraev, F. M. (2021). Results of endoscopic treatment of benign prostatic hyperplasia in patients with metabolic syndrome. International Journal of Health & Medical Sciences, 5(1), 21-25. https://doi.org/10.21744/ijhms.v5n1.1811
Santra A, Dutta P, Manjhi R, Pothal S. Clinico-radiologic and spirometric profile of an Indian population with post-tuberculous obstructive airway disease. Journal of clinical and diagnostic research: JCDR. 2017 Mar;11(3):OC35
Suryasa, I. W., Rodríguez-Gámez, M., & Koldoris, T. (2021). Health and treatment of diabetes mellitus. International Journal of Health Sciences, 5(1), i-v. https://doi.org/10.53730/ijhs.v5n1.2864
Verma SK, Narayan KV, Kumar S. A study on prevalence of obstructive airway disease among post pulmonary tuberculosis patients. Pulmon. 2009;11(1):4-7.
WHO Global TB report 2021 Jeremiah C, Petersen E, Nantanda R, Mungai BN, Migliori GB, Amanullah F, Lungu P, Ntoumi F, Kumarasamy N, Maeurer M, Zumla A. The WHO Global Tuberculosis 2021 Report–not so good news and turning the tide back to End TB. International Journal of Infectious Diseases. 2022 Mar 20.
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