Cytogenetic study of types anemia patients
Keywords:
Anemia, chromosomal aberrations, thier cytogenetic anemiaAbstract
Background and Objectives: studying chromosomal changes for anemia patients of children age (3month-12years ) in the city of kut and diagnosing those abnormalities resulting from having anemia Methods: The chromosomes of anemia Patients to were analyzed and studied using cytogenetic analysis to detect chromosomal aberrations caused by having anemia after collecting blood samples from children patients in Al-Karama Teaching Hospital as well as from the to the patients clinics in Kut.Results: Chromosomal analysis of all subjects showed chromosomal aberrations, and most of the aberrations were structural and numerical changes that structural in the (1 out28)of the chromosomal abnormality was for the gap chromosome type, chromosomal-aberration dicentric (2 out 28) ,chromosomal-aberration deletion (1-28) addition to the short chromosomal and clumped metaphase of patient .As well as changes chromosomal aberrtion were numerical in the chromosomal –aberration absent (1-28)it was due to leukemia that was anemia causative .And classification of anemias based on Size of red blood cells Microcytic, Normocytic , Macrocytic The most commn prevalent and preventable form of microcytic anemia is iron deficiency anemia Conclusion: Chromosome abnormlity (abnormal number ,structural )it occure ( abnormlity structural)in our study present short chromosomes and clumped metaphase,deletion ,chromsomes gap ,chromosome dicentric.
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