A comparative study between general anesthesia and conscious sedation for oocyte retrieval on hemodynamic recovery and oocyte quality

Hind Abd Al Rassol Mugeir; Raed Ghazi Al-Zubaidi; Hayder A. L. Mossa

doi:10.53730/ijhs.v6nS6.11256

Authors

Hind Abd Al Rassol Mugeir M.B.Ch., B.D.G.O. High Institute for Infertility, Diagnosis and Assisted Reproductive Technologies-Al-Nahrain University-Baghdad-IRAQ
Raed Ghazi Al-Zubaidi Assist. Prof., Board Degree in Anesthesia and RCU, High Institute for Infertility, Diagnosis and Assisted Reproductive Technologies-Al-Nahrain University-Baghdad-IRAQ
Hayder A. L. Mossa Assist. Prof., Ph.D. Reproductive Physiology and Laboratory Assisted Reproductive, High Institute for Infertility, Diagnosis and Assisted Reproductive Technologies-Al-Nahrain University-Baghdad-IRAQ

Keywords:

conscious sedation, general anesthesia, oocyte retrieval

Abstract

Background: In vitro fertilization (IVF) is a four-stage procedure, ovarian stimulation and monitoring, oocyte retrieval, fertilization and embryo transfer. Transvaginal ultrasound–guided follicle aspiration is the most common method for oocyte retrieval in assisted reproductive technologies, it is increasingly performed as an outside procedure. Objective: To compare between general Anesthesia and Conscious Sedation according to Oocyte Retrieval on hemodynamic recovery and oocyte quality. Methods: Seventy women underwent oocyte retrieval in the period from November 2021 till June 2022 at High Institute of Infertility Diagnosis and Assisted Reproductive Technique, Reproductive Physiology, Al-Nahrain University in Baghdad, Iraq, were included in this study. Results: Mean time needed for operation was 9.06± 1.39 minutes in conscious group and 9.84± 1.11 minutes in GA group, and the recovery time needed was 2.31± 0.47 hours in conscious group and 10.78± 1.87hours in GA group. Conclusion: Significant decrease in duration of operation in conscious group than that in general anesthesia group (P=0.01), moreover, highly significant decrease in recovery time in conscious group than that in GA group (P<0.001)

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References

Adamson GD, de Mouzon J, Chambers GM, Zegers-Hochschild F, Mansour R, Ishihara O, Banker M, Dyer S. International Committee for Monitoring Assisted Reproductive Technology: world report on assisted reproductive technology, 2011. Fertility and sterility. 2018 Nov 1;110(6):1067-80.

Buisman ET, Grens H, Wang R, Bhattacharya S, Braat DD, Huppelschoten AG, van der Steeg JW. Trends in research on pain relief during oocyte retrieval for IVF/ICSI: a systematic, methodological review. Human Reproduction Open. 2022;2022(1):hoac006.

Choufani S, Turinsky AL, Melamed N, Greenblatt E, Brudno M, Bérard A, Fraser WD, Weksberg R, Trasler J, Monnier P. Impact of assisted reproduction, infertility, sex and paternal factors on the placental DNA methylome. Human molecular genetics. 2019 Feb 1;28(3):372-85.

Farzi F, Mehrafza M, Mirmansouri A, Sorouri ZZ, Roushan ZA, Raoufi A, Shalkohi R, Samadnia S, Hosseini A. Hemodynamic parameters and reproductive outcome after intracytoplasmic sperm injection and fresh embryo transfer in patients undergoing oocyte retrieval with general anesthesia using fentanyl, remifentanil or alfentanil–a randomized clinical trial. Taiwanese Journal of Obstetrics and Gynecology. 2019 Jul 1;58(4):536-40.

Gandamayu, I. B. M., Antari, N. W. S., & Strisanti, I. A. S. (2022). The level of community compliance in implementing health protocols to prevent the spread of COVID-19. International Journal of Health & Medical Sciences, 5(2), 177-182. https://doi.org/10.21744/ijhms.v5n2.1897

Garolla A, Pizzol D, Carosso AR, Borini A, Ubaldi FM, Calogero AE, Ferlin A, Lanzone A, Tomei F, Engl B, Rienzi L. Practical clinical and diagnostic pathway for the investigation of the infertile couple. Frontiers in Endocrinology. 2021:1032.

Khetarpal R, Chatrath V, Kaur P, Trikha A. Anaesthesia for assisted reproductive technology (ART): A narrative review. Journal of Obstetric Anaesthesia and Critical Care. 2022 Jan 1;12(1):5.

Lier MC, Douwenga WM, Yilmaz F, Schats R, Hompes PG, Boer C, Mijatovic V. Patient‐controlled remifentanil analgesia as alternative for pethidine with midazolam during oocyte retrieval in IVF/ICSI procedures: a randomized controlled trial. Pain Practice. 2015 Jun;15(5):487-95.

Matsota P, Sidiropoulou T, Vrantza T, Boutsikou M, Midvighi E, Siristatidis C. Comparison of two different sedation protocols during transvaginal oocyte retrieval: Effects on propofol consumption and IVF outcome: A prospective cohort study. Journal of clinical medicine. 2021 Mar 1;10(5):963.

Mohsin HA, Jwad MA, Reshan RG. Effect of drugs used in general anesthesia on oocyte and embryo quality in Iraqi infertile females undergoing intracytoplasmic sperm injection. Iraqi Journal of Embryos and Infertility Researches. 2020 Dec 16;10(1):83-100.

Singhal H, Premkumar PS, Chandy A, Kunjummen AT, Kamath MS. Patient experience with conscious sedation as a method of pain relief for transvaginal oocyte retrieval: A cross sectional study. Journal of Human Reproductive Sciences. 2017 Apr;10(2):119.

Suryasa, I. W., Rodríguez-Gámez, M., & Koldoris, T. (2021). Get vaccinated when it is your turn and follow the local guidelines. International Journal of Health Sciences, 5(3), x-xv. https://doi.org/10.53730/ijhs.v5n3.2938

Teixeira DM, Miyague AH, Barbosa MA, Navarro PA, Raine‐Fenning N, Nastri CO, Martins WP. Regular (ICSI) versus ultra‐high magnification (IMSI) sperm selection for assisted reproduction. Cochrane Database of Systematic Reviews. 2020(2).

Vioreanu AM. The psychological impact of infertility. Directions for the development of interventions. Mental Health: Global Challenges Journal. 2021 Oct 25;4(1).