Comparative study of copper, zinc levels in uncontrolled type 2 diabetes mellitus with normal subjects
Keywords:
copper, zinc, HBA1c, uncontrolled type 2 diabetes mellitusAbstract
accounts for majority of the cases, can lead to multiorgan complications. Direct association of minerals , Trace elements and vitamins in the pathogenesis and natural cause of type 2 diabetes mellitus has been observed in many research studies. Aim: To estimate the levels of Copper , Zinc and HBA1c in uncontrolled Type 2 Diabetes mellitus patient. Material and methods: A cross sectional analytical studies was conducted in DR B R AMC. Study group included 40 known case of uncontrolled Diabetes mellitus. Results: In the present Study serum copper levels in uncontrolled Type 2 Diabetes Mellitus patients was 204.3 ± 49.0 and in controls it was132.4 ± 20.2. There was a statistically significant increase in the mean copper values in uncontrolled Type 2 Diabetes Mellitus patients (P< 0.0001). Serum Zinc levels in uncontrolled Type 2 Diabetes Mellitus patients was 174.7 ± 31.0 µg/dl and in the controls it was 207.4 ± 36.6 µg/dl. There was a statistically significant decrease in the mean Zinc values (P<0.0001). Conclusion: Trace elements play a vital role in maintaining the normal metabolism and homeostasis.
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Abdul hamid zargar, Nissar ahmad shah, Shariq rashid masoodi,et al. Copper, Zinc, and Magnesium levels in non-insulin dependent Diabetes mellitus 1998;74:665-668.
Alemayehu toma, Eyasu makonnen, Getnet yimer . Role of zinc in diabetes mellitus, oxidative stress and other human healthy: a review article 2013; 1(11): 411-426.
Bibi hajra, Shaukat ali orakzai, Uzma faryal, et al. Insulin sensitivity to trace metals (chromium, manganese) in type 2 Diabetic patients and non Diabetic individuals 2016;28(3): 534-536.
Ewelina król, Zbigniew krejpcio, Sławomir michalak et al. Effects of combined dietary chromium(iii) propionate complex and thiamine supplementation on insulin sensitivity, blood biochemical indices, and mineral levels in high-fructose-fed rats 2012; 150:350–359.
Jayawardena R, Ranasinghe p, Galappatthy P, et al. Effects of zinc supplementation on diabetes mellitus: a systematic review and meta-analysis 2012; 4:13.
Jeff geohas, Anne daly, Vijaya juturu, et al. Chromium picolinate and Biotin combination reduces atherogenic index of plasma in patients with type 2 diabetes mellitus: a placebo-controlled, double-blinded, randomized clinical trial 2007; 333(3): 145–153.
Kyria jayanne clímaco cruz, Ana raquel soares de oliveira, Dilina do nascimento marreiro. Antioxidant role of zinc in diabetes mellitus 2015 ; 6(2): 333-337.
Mahardika, I. M. R., Suyasa, I. G. P. D., Kamaryati, N. P., & Wulandari, S. K. (2021). Health literacy is strongest determinant on self-monitoring blood glucose (SMBG) type 2 DM patients during COVID-19 pandemic at public health centre in Tabanan Regency. International Journal of Health & Medical Sciences, 4(3), 288-297. https://doi.org/10.31295/ijhms.v4n3.1752
Priyanga Ranasinghe, Shehani pigera, Priyadarshani galappatthy, et al. zinc and diabetes mellitus: understanding molecular mechanisms and clinical implications 2015; 23:44
Priyanka mor, Anjana kanwar rathore , Vanita sonagra, et al. a Study of serum copper, zinc and magnesium in type 2 Diabetes mellitus with complications and without complications 2020; 13: 1927-1930.
Ratnawati, I. G. A. A., Suandayani, N. K. T., & Sutapa, G. N. (2019). The linearity of x-ray devices radiation output and its relationship with patient thickness. International Journal of Physical Sciences and Engineering, 3(3), 1–6. https://doi.org/10.29332/ijpse.v3n3.351
Robert m. walter, jr , Janet y. uriu-hare, Katherine lewis olin, et al. Copper, Zinc, Manganese, and magnesium status and complications of diabetes mellitus 1991; 14 : 1050-1056.
Sonny bherwani, Ashok kumar ahirwar, Saumya, et al. effect of Serum copper levels in type 2 diabetes mellitus with nephropathy: a case control study in north Indian population. 2017; 5(1), 420-424.
Suryasa, I. W., Rodríguez-Gámez, M., & Koldoris, T. (2021). Health and treatment of diabetes mellitus. International Journal of Health Sciences, 5(1), i-v. https://doi.org/10.53730/ijhs.v5n1.2864
Tawfeeq f. r. al-auqbi , et al. Serum copper, zinc and cu/zn ratio in diabetics 2007; 20(3): 419- 425.
Thiyam romola devi, Davina hijam, Abhishek dubey, et al. Study of serum zinc and copper levels in type 2 Diabetes Mellitus 2018; 3: 2454-7379.
Thowyba elhadi omer, Abdelwahab abdien saeed and Salman taha ahmed elmukashfi. assessment of serum zinc and copper levels among sudanese patients with diabetes mellitus type 2 in khartoum state-sudan 2020; 32(4): 120-125.
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