Duodenal ulcer and gastric cancer patients infected with Helicobacter Pylori in AL-Najaf City, Iraq
Keywords:
Duodenal Ulcer, Gastric Cancer, Male, Female, Helicobacter PyloriAbstract
A case-control study was carried out in Al- Sader Medical City in AL-Najaf Governorate, Iraq, during period from 1/9/2021 to 1/3/2022. Helicobacter pylori (H. pylori) Antigen Rapid Test Cassette (Feces) has been used to diagnosis all patients infected with H. pylori. All patients with duodenal ulcers and gastric cancer have been diagnosed by a physician using an endoscope and biopsy, respectively, in the department of tumors at AL-Sader Medical City. The results proved that there were 27 patients; 11 male (40.7%) and 16 female (59.3%) infected with H.pylori. Age group 20-30 was the highest infected with H.pylori (14 patients, 51.9%) followed by 31-40 (8 patients 29.6%), 41-50 (4 patients 14.8%) and 51-60 (1 patient 3.7%). Conclusions: Helicobacter Pylori may cause the most cases of duodenal ulcer and gastric cancer in patients that infected with this bacterium.
Downloads
References
Alipour, M., 2020. Molecular Mechanism of Helicobacter pylori-Induced Gastric Cancer. Journal of gastrointestinal cancer, pp.1-8. doi.org/10.1007/s12029-020-00518-5
Aljanaby, A.A.J., Al-Faham, Q.M.H., Aljanaby, I.A.J. and Hasan, T.H., 2022. Immunological role of cluster of differentiation 56 and cluster of differentiation 19 in patients infected with mycobacterium tuberculosis in Iraq. Gene Reports, p.101514. doi.org/10.1016/j.genrep.2022.101514
Chonwerawong, M. and Ferrero, R.L., 2017. Regulation and functions of inflammasome-mediated cytokines in Helicobacter pylori infection. Microbes and infection, 19(9-10), pp.449-458. doi: 10.1016/j.micinf.2017.06.005
Eslami, M., Yousefi, B., Kokhaei, P., Arabkari, V. and Ghasemian, A., 2019. Current information on the association of Helicobacter pylori with autophagy and gastric cancer. Journal of cellular physiology, 234(9), pp.14800-14811. doi.org/10.1002/jcp.28279
Hadi, H. I. and Aljanaby, A. A. J. (2022). Helicobacter Pylori-oncogenic protein cytotoxin-associated gene A and assessment of CD14 and CD163 in duodenal ulcer and gastric cancer patients. International Journal of Health Sciences, 6(S2), 839–851. https://doi.org/10.53730/ijhs.v6nS2.5134
Jolaiya, T.F., Fowora, M.A., Onyekwere, C., Ugiagbe, R., Agbo, I.I., Lesi, O., Ndububa, D.A., Adekanle, O., Njom, H.A., Idowu, A. and Adeleye, I.A., 2020. Duodenal ulcer promoting gene (DupA), plasticity region genes and sigma factors in H. pyloristrains from Nigeria. The Journal of Infection in Developing Countries, 14(02), pp.162-168. doi: 10.3855/jidc.11746
Lehours, P. and Robinson, K., 2020. Helicobacter, inflammation, immunology and vaccines. Helicobacter, 25, p.e12737. doi: 10.1111/hel.12737
Medhat, A. R., and Aljanaby, A. A. J. (2022). Assessment of some immune markers in typhoid-patients: A case control study . International Journal of Health Sciences, 6(S1), 4199–4210. https://doi.org/10.53730/ijhs.v6nS1.5592
Mohammed, E.H. and Aljanaby, A.A.J., 2020. Galectin3 and CD16 play an important immunological role in patients infected with Salmonella typhi. Int. J. Res. Pharm. Sci., 2020, 11(3), 4162-4169
Suryasa, I. W., Rodríguez-Gámez, M., & Koldoris, T. (2021). Get vaccinated when it is your turn and follow the local guidelines. International Journal of Health Sciences, 5(3), x-xv. https://doi.org/10.53730/ijhs.v5n3.2938
Thaib, P. K. P., & Rahaju, A. S. (2022). Clinicopathological profile of clear cell renal cell carcinoma. International Journal of Health & Medical Sciences, 5(1), 91-100. https://doi.org/10.21744/ijhms.v5n1.1846
Zhang, Q., Ding, J., Liu, J., Wang, W., Zhang, F., Wang, J. and Li, Y., 2016. Helicobacter pylori-infected MSCs acquire a pro-inflammatory phenotype and induce human gastric cancer migration by promoting EMT in gastric cancer cells. Oncology letters, 11(1), pp.449-457. doi: 10.3892/ol.2015.3897
Zhuang, Y., Cheng, P., Liu, X.F., Peng, L.S., Li, B.S., Wang, T.T., Chen, N., Li, W.H., Shi, Y., Chen, W. and Pang, K.C., 2015. A pro-inflammatory role for Th22 cells in Helicobacter pylori-associated gastritis. Gut, 64(9), pp.1368-1378. doi: 10.1136/gutjnl-2014-307020
Published
How to Cite
Issue
Section
Copyright (c) 2022 International journal of health sciences

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Articles published in the International Journal of Health Sciences (IJHS) are available under Creative Commons Attribution Non-Commercial No Derivatives Licence (CC BY-NC-ND 4.0). Authors retain copyright in their work and grant IJHS right of first publication under CC BY-NC-ND 4.0. Users have the right to read, download, copy, distribute, print, search, or link to the full texts of articles in this journal, and to use them for any other lawful purpose.
Articles published in IJHS can be copied, communicated and shared in their published form for non-commercial purposes provided full attribution is given to the author and the journal. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
This copyright notice applies to articles published in IJHS volumes 4 onwards. Please read about the copyright notices for previous volumes under Journal History.