Efficacy of fluoride varnish containing xylitol coated calcium phosphate or potassium nitrate gel versus conventional fluoride varnish in management of hypersensitivity of exposed root surfaces in adult patients: A randomized clinical trial

https://doi.org/10.53730/ijhs.v6nS7.12066

Authors

  • Peter Edward Ibrahim Assistant Lecturer, Department of Conservative Dentistry, Faculty of Dentistry, Cairo University, Egypt
  • Mohamed Adel Ezzat Professor of Conservative Dentistry, Faculty of Dentistry, Cairo University, Egypt
  • Amir Hafez Ibrahim Assistant professor of Conservative Dentistry, Faculty of Dentistry, Cairo University, Egypt
  • Omar Osama Shaalan Lecturer of Conservative Dentistry, Faculty of Dentistry, Cairo University, Egypt

Keywords:

Hypersensitivity, , Embrace varnish ™, Ultra EZ™ gel, Potassium nitrate, Fluoride varnish, FluoroDose™, Exposed roots

Abstract

Objective: This clinical trial was conducted to compare the efficacy of fluoride varnish containing xylitol coated calcium and phosphate or potassium nitrate gel versus conventional fluoride varnish in the management of hypersensitivity of non-carious exposed root surfaces in adult patients. Material and Methods: 35 patients having 105 hypersensitive teeth were randomly allocated to be treated either using Embrace varnish (PULPDENT Corporation, Watertown, MA, USA) or UltraEz gel (Ultradent Products Inc. South Jordan, UT, USA) or Fluoride varnish FluoroDose (Centrix Inc., Milford, Connecticut, USA), all agents were used according to the manufacturers’ instructions. Hypersensitivity scores were assessed using the visual analogue scale (VAS), after applying different stimuli. The assessment was done at baseline, after 4 hours of application, after two days, then after 4, 8 and 12 months. Results: UltraEZ gel showed the best immediate relief with a significant difference from other treatment methods, fluoride varnish showed the best relief at both short and long term follow up periods. Embrace varnish showed the least success in reducing hypersensitivity.  Conclusions: Fluoride varnish showed the best reduction in hypersensitivity values while UltraEZ showed the best immediate relief and Embrace varnish showed the least efficacy

 

Downloads

Download data is not yet available.

References

Naik VK, Jacob CA, Nainar DA. Assessment of non-carious root surface defects in areas of gingival recession: A descriptive study. Journal of clinical and experimental dentistry. 2016;8(4):e397-e402.

Arthur RA, Martins VB, de Oliveira CL, Leitune VC, Collares FM, Magalhaes AC, et al. Effect of over-the-counter fluoridated products regimens on root caries inhibition. Archives of oral biology. 2015;60(10):1588-94.

Owoturo O, Loto A, Awotile A, Oyapero A, Ebigwei S. Comparison of two different forms of varnishes in the treatment of dentine hypersensitivity: A subject-blind clinical study in Lagos State university teaching hospital. Archives of Medicine and Health Sciences. 2017;5(2):191-9.

Pandit N, Gupta R, Bansal A. Comparative evaluation of two commercially available desensitizing agents for the treatment of dentinal hypersensitivity. Indian Journal of Dental Research. 2012;23(6):778-83.

Petersson LG. The role of fluoride in the preventive management of dentin hypersensitivity and root caries. Clinical oral investigations. 2013;17 Suppl 1(Suppl 1):S63-71.

Machado AC, Rabelo FEM, Maximiano V, Lopes RM, Aranha ACC, Scaramucci T. Effect of in-office desensitizers containing calcium and phosphate on dentin permeability and tubule occlusion. Journal of dentistry. 2019;86:53-9.

The Editors Pulpdent lanches Embrace Varnish. Dimensions of Dental Hygiene. 2012 (https://dimensionsofdentalhygiene.com/pulpdent-lanches-embrace-varnish/)

Bijur PE, Silver W, Gallagher EJ. Reliability of the visual analog scale for measurement of acute pain. Acad Emerg Med. 2001;8(12):1153-7.

Hall C, Sufi F, Wang N, Goyal CR. Efficacy of an experimental 3% potassium nitrate mouthwash in providing long-term relief from dentin hypersensitivity: An 8-week randomized controlled study (Study 1). American journal of dentistry. 2017;30(1):27-34.

Ahmed DEEM, Abielhassan MH, Hamza HSE, Haridy MF, Mamdouh M. Sylc Air Polishing Versus Fluoride Varnish Application in Managing Dentin Hypersensitivity in Non-Carious Cervical Lesions: A Randomized Clinical Trial. TODENTJ. 2020;14(1):120-6.

Gillam D, Chesters R, Attrill D, Brunton P, Slater M, Strand P, et al. Dentine hypersensitivity--guidelines for the management of a common oral health problem. Dental update. 2013;40(7):514-6, 8-20, 23-4.

Clark D, Levin L. Non-surgical management of tooth hypersensitivity. International dental journal. 2016;66(5):249-56.

Marto CM, Baptista Paula A, Nunes T, Pimenta M, Abrantes AM, Pires AS, et al. Evaluation of the efficacy of dentin hypersensitivity treatments-A systematic review and follow-up analysis. Journal of oral rehabilitation. 2019;46(10):952-90.

de Oliveira RP, Alencar CM, Silva FA, Magno MB, Maia LC, Silva CM. Effect of desensitizing agents on dentin hypersensitivity after non-surgical periodontal therapy: A systematic review and meta-analysis. Journal of dentistry. 2020;103:103498.

Shiau HJ. Dentin hypersensitivity. The journal of evidence-based dental practice. 2012;12(3 Suppl):220-8.

Bae JH, Kim YK, Myung SK. Desensitizing toothpaste versus placebo for dentin hypersensitivity: a systematic review and meta-analysis. Journal of clinical periodontology. 2015;42(2):131-41.

Sharma S, Shetty NJ, Uppoor A. Evaluation of the clinical efficacy of potassium nitrate desensitizing mouthwash and a toothpaste in the treatment of dentinal hypersensitivity. Journal of clinical and experimental dentistry. 2012;4(1):e28-33.

West NX, Seong J, Davies M. Management of dentine hypersensitivity: efficacy of professionally and self-administered agents. Journal of clinical periodontology. 2015;42 Suppl 16:S256-302.

Camilotti V, Zilly J, Busato Pdo M, Nassar CA, Nassar PO. Desensitizing treatments for dentin hypersensitivity: a randomized, split-mouth clinical trial. Brazilian oral research. 2012;26(3):263-8.

Duckworth RM, Jones S. On the relationship between the rate of salivary flow and salivary fluoride clearance. Caries Res. 2015;49(2):141-6.

Earl JS, Leary RK, Muller KH, Langford RM, Greenspan DC. Physical and chemical characterization of dentin surface following treatment with NovaMin technology. The Journal of clinical dentistry. 2011;22(3):62-7.

Sowinski J, Ayad F, Petrone M, DeVizio W, Volpe A, Ellwood R, et al. Comparative investigations of the desensitising efficacy of a new dentifrice. Journal of clinical periodontology. 2001;28(11):1032-6.

Pradeep AR, Sharma A. Comparison of clinical efficacy of a dentifrice containing calcium sodium phosphosilicate to a dentifrice containing potassium nitrate and to a placebo on dentinal hypersensitivity: a randomized clinical trial. Journal of periodontology. 2010;81(8):1167-73.

Hjermstad MJ, Fayers PM, Haugen DF, Caraceni A, Hanks GW, Loge JH, et al. Studies comparing Numerical Rating Scales, Verbal Rating Scales, and Visual Analogue Scales for assessment of pain intensity in adults: a systematic literature review. J Pain Symptom Manage. 2011;41(6):1073-93.

Hickel R, Roulet JF, Bayne S, Heintze SD, Mjör IA, Peters M, et al. Recommendations for conducting controlled clinical studies of dental restorative materials. Clinical oral investigations. 2007;11(1):5-33.

Kumari M, Naik SB, Martande SS, Pradeep AR, Singh P. Comparative efficacy of a herbal and a non-herbal dentifrice on dentinal hypersensitivity: a randomized, controlled clinical trial. J Investig Clin Dent. 2016;7(1):46-52.

Majji P, Murthy KR. Clinical efficacy of four interventions in the reduction of dentinal hypersensitivity: A 2-month study. Indian journal of dental research: official publication of Indian Society for Dental Research. 2016;27(5):477-82.

Mahesuti A, Duan Y, Wang G, Cheng X, Matis B. Short-term Efficacy of Agents Containing KNO3 or CPP-ACP in Treatment of Dentin Hypersensitivity. Chin J Dent Res. 2014;17(1):43-7.

Raichur PS, Setty SB, Thakur SL. Comparative evaluation of diode laser, stannous fluoride gel, and potassium nitrate gel in the treatment of dentinal hypersensitivity. Gen Dent. 2013;61(3):66-71.

Suri I, Singh P, Shakir QJ, Shetty A, Bapat R, Thakur R. A comparative evaluation to assess the efficacy of 5% sodium fluoride varnish and diode laser and their combined application in the treatment of dentin hypersensitivity. Journal of Indian Society of Periodontology. 2016;20(3):307-14.

Anderson CJ, Kugel G, Gerlach R. A randomized, controlled comparison of two professional dentin desensitizing agents immediately post-treatment and 2 months post-treatment. American journal of dentistry. 2018;31(6):297-302.

Rosaiah.K, Aruna.K. Clinical Efficacy of Amorphous Calcium Phosphate, G . C . Tooth Mousse and Gluma Desensitizer in Treating Dentin Hypersensitivity. International Journal of Dental Clinics. 2011;3:1+.

Bou Chebel F, Zogheib CM, Baba NZ, Corbani KA. Clinical Comparative Evaluation of Nd:YAG Laser and a New Varnish Containing Casein Phosphopeptides-Amorphous Calcium Phosphate for the Treatment of Dentin Hypersensitivity: A Prospective Study. J Prosthodont. 2018;27(9):860-7.

Talioti E, Hill R, Gillam DG. The Efficacy of Selected Desensitizing OTC Products: A Systematic Review. ISRN Dent. 2014;2014:865761.

Wegehaupt FJ, Tauböck TT, Stillhard A, Schmidlin PR, Attin T. Influence of extra- and intra-oral application of CPP-ACP and fluoride on re-hardening of eroded enamel. Acta Odontol Scand. 2012;70(3):177-83.

Pishevar L, Farhad SZ, Mirzakhani M, Haghayegh N, Ansarinejad M. Comparison the effect of casein phosphopeptide amorphous calcium phosphate and fluoride varnish on dentin hypersensitivity reduction. Caspian-J-Dent-Res. 2015;4(2):20-6.

Milburn JL, Henrichs LE, Banfield RL, Stansell MJ, Kraig SE, ewalle. Substantive Fluoride Release from a New Fluoride Varnish Containing CXP. Dentistry 3000. 2015;5:1-6.

Uegi L, Federic T, Stefano S. Effectiveness of an in-office calcium-phosphate-based desensitizer: A six-month randomized-controlled trial and a SEM study of in-vivo treated teeth. Indian Journal of Conservative and Endodontics. 2017 Oct;2(4):119-27.

Published

23-08-2022

How to Cite

Ibrahim, P. E., Ezzat, M. A., Ibrahim, A. H., & Shaalan, O. O. (2022). Efficacy of fluoride varnish containing xylitol coated calcium phosphate or potassium nitrate gel versus conventional fluoride varnish in management of hypersensitivity of exposed root surfaces in adult patients: A randomized clinical trial. International Journal of Health Sciences, 6(S7), 2760–2776. https://doi.org/10.53730/ijhs.v6nS7.12066

Issue

Section

Peer Review Articles