Clinical evaluation of bioactive resin based pits & fissures sealants versus conventional resin based pits & fissures sealants in caries susceptible fissures in permanent molars: A randomized controlled
Keywords:
Bioactive, Caries, Fluoride, Retention, SealantAbstract
Objectives: This study was carried out to evaluate the clinical performance of bioactive versus fluoride releasing resin-based pits and fissure sealants in molars in high caries risk patients regarding retention and caries incidence. Material and methods: A total of 38 participants received 38 pits and fissure sealants randomly using either; BioCoat™ by Premier® (Plymouth Meeting, Pennsylvania,USA) or Clinpro™ by 3M™ ESPE (St. Paul, Minnesota, USA) , all materials were utilized obeying manufacturers’ instructions. Sealants were evaluated using Simonsen’s criteria for retention and using VistaProof fluorescent camera for caries detection around sealants or in presealed fissures by two blinded assessors after 6-and 12- months. Chi square test was used to associate between the type of sealants and their clinical performance. Relative risk was used to assess the clinical significance. Survival rate was analysed using Kaplan-meier and Log-rank test Results: For retention, comparison between both sealants have shown no statistically significant difference throughout different follow up periods; baseline, 6 and 12 months (P = 1.0000, P = 0.9277 and P = 0.3185) respectively. There was 16% less risk for failure in retention for Biocoat sealant when compared to Clinpro sealant after 12 months (RR= 0.8366(95% CI 0.4306 to 1.6252; P =0.5985).
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Marsh PD, Head DA, Devine DA. Dental plaque as a biofilm and a microbial community - Implications for treatment. J Oral Biosci. 2015;57(4):185-191. doi:10.1016/j.job.2015.08.002
Zhang W, Chen X, Fan M, Mulder J, Frencken JE. Retention rate of four different sealant materials after four years. Oral Health Prev Dent. 2017;15(4):307-314. doi:10.3290/j.ohpd.a38743
Banas JA, Drake DR. Are the mutans streptococci still considered relevant to understanding the microbial etiology of dental caries? BMC Oral Health. 2018;18(1). doi:10.1186/s12903-018-0595-2
Tanner ACR, Kressirer CA, Rothmiller S, Johansson I, Chalmers NI. The Caries Microbiome: Implications for Reversing Dysbiosis. Adv Dent Res. 2018;29(1):78-85. doi:10.1177/0022034517736496
Carvalho JC. Caries process on occlusal surfaces: Evolving evidence and understanding. Caries Res. 2014;48(4):339-346. doi:10.1159/000356307
Khanna R, Ramesh KP, Singh N. Morphology of Pits and Fissures Reviewed through Scanning Electron Microscope. Dentistry. 2015;5(4). doi:10.4172/2161-1122.1000287
Liu BY, Lo ECM, Chu CH, Lin HC. Randomized trial on fluorides and sealants for fissure caries prevention. J Dent Res. 2012;91(8):753-758. doi:10.1177/0022034512452278
Wright JT, Crall JJ, Fontana M, et al. Evidence-based clinical practice guideline for the use of pit-and-fissure sealants: A report of the American Dental Association and the American Academy of Pediatric Dentistry. J Am Dent Assoc. 2016;147(8):672-682.e12. doi:10.1016/j.adaj.2016.06.001
Stahl JW, Katz R V. Occlusal Dental Caries Incidence and Implications for Sealant Programs in a US College Student Population. J Public Health Dent. 1993;53(4):212-218. doi:10.1111/j.1752-7325.1993.tb02706.x
Gore D. The use of dental sealants in adults: a long-neglected preventive measure. Int J Dent Hyg. 2009;8:198-203. doi:10.1111/j.1601-5037.2009.00425.x
Splieth CH, Ekstrand KR, Alkilzy M, et al. Sealants in dentistry: Outcomes of the ORCA saturday afternoon symposium 2007. Caries Res. 2010;44(1):3-13. doi:10.1159/000271591
Bakhshandeh A, Qvist V, Ekstrand KR. Sealing occlusal caries lesions in adults referred for restorative treatment: 2-3 years of follow-up. Clin Oral Investig. 2012;16(2):521-529. doi:10.1007/s00784-011-0549-4
Tarle Z, Par M. Bioactive dental composite materials. Rad Hrvat Akad Znan i Umjet Med Znan. 2018;533(43):83-100. doi:10.21857/mnlqgc02ky
Burbank BD, Cooper RL, Kava A, et al. Ion release and in vitro enamel fluoride uptake associated with pit and assure sealants containing microencapsulated remineralizing agents. Am J Dent. 2017;30(2):59-64. http://www.ncbi.nlm.nih.gov/pubmed/29178765. Accessed December 10, 2018.
Ratnaditya A, Kumar MGM, Jogendra SSA, Zabirunnisa M, Kandregula CR, Kopuri RKC. Clinical evaluation of retention in hydrophobic and hydrophillic pit and fissure sealants-a two year follow-up study. J Young Pharm. 2015;7(3):171-179. doi:10.5530/jyp.2015.3.6
Hegde RJ, Coutinho RC. Comparison of different methods of cleaning and preparing occlusal fissure surface before placement of pit and fissure sealants: An in vivo study. J Indian Soc Pedod Prev Dent. 2016;34(2):111-114. doi:10.4103/0970-4388.180403
Jaikumpun P, Kiattang K, Sangsue T, et al. The Effect of Different Phosphoric Acid-etching Times on Microtensile Bond Strength of Sealant on Different Enamel Substrates. Chiang Mai Dent J. 2017;38(1):101-112. https://he01.tci-thaijo.org/index.php/cmdj/article/view/249158. Accessed December 17, 2021.
Simonsen RJ. Retention and effectiveness of dental sealant after 15 years. J Am Dent Assoc. 1991;122(11):34-42. doi:10.14219/jada.archive.1991.0289
Rajashekar Reddy V, Chowdhary N, Mukunda KS, Kiran NK, Kavyarani BS, Pradeep MC. Retention of resin-based filled and unfilled pit and fissure sealants: A comparative clinical study. Contemp Clin Dent. 2015;6(5):S18-S23. doi:10.4103/0976-237X.152932
Baheti AS, Kumar P, Gupta S, Bhayya DP, Shyagali TR. Assessment of Clinical Success of Three Sealants: Embrace-WetBond, Clinpro, and Helioseal-F in Permanent Molars: An In Vivo Study. J South Asian Assoc Pediatr Dent. 2020;3(1):7-13. doi:10.5005/jp-journals-10077-3035
Bagheri E, Sarraf Shirazi A, Shekofteh K. Comparison of the Success Rate of Filled and Unfilled Resin- Based Fissure Sealants: A Systematic Review and Meta-analysis. Front Dent. 2022;19. doi:10.18502/fid.v19i10.8855
Beauchamp J, Caufield PW, Crall JJ, et al. Evidence-Based Clinical Recommendations for the Use of Pit-and-Fissure Sealants: A Report of the American Dental Association Council on Scientific Affairs. Dent Clin North Am. 2009;53(1):131-147. doi:10.1016/j.cden.2008.09.003
Reddy PVR, Shigli A, Shirol D, Deshpande S, Hugar S, Poonacha K. The evaluation of different methods viz., acid etch and by air abrasion on retentivity of fissure sealant after 6 months: A clinical study. J Sci Soc. 2014;41(1):16. doi:10.4103/0974-5009.126709
Lo Y-F, Crispin A, Kessler A, Hickel R, Kühnisch J. What is an Appropriate Etching Time For Sealant Application on Permanent Molars? Results from a Meta-Analysis. J Adhes Dent. 2019;21(6):487-495. doi:10.3290/j.jad.a43181
Davidson M, Greving T, Mchale WA, Latta MA, Gross S. Synthesis and Characterization of Ion Permeable Microcapsules for Remineralization IADR Abstract Archives.; 2011. https://iadr.abstractarchives.com/abstract/2011sandiego-148435/synthesis-and-characterization-of-ion-permeable-microcapsules-for-remineralization. Accessed November 24, 2021.
Attar N, Melek T. Fluoride release and uptake capacities of fluoride-releasing restorative materials | Request PDF. Oper Dent. 2003;28(4):395-402. https://www.researchgate.net/publication/10648558_Fluoride_release_and_uptake_capacities_of_fluoride-releasing_restorative_materials. Accessed May 29, 2022.
Şişmanoğlu S. Fluoride Release of Giomer and Resin Based Fissure Sealants. Odovtos - Int J Dent Sci. 2019;21(2):45-52. doi:10.15517/ijds.v0i0.36860
Bandekar S, Patil S, Dudulwar D, Moogi P, Ghosh S, Kshirsagar S. Remineralization potential of fluoride, amorphous calcium phosphate-casein phosphopeptide, and combination of hydroxylapatite and fluoride on enamel lesions: An in vitro comparative evaluation. J Conserv Dent. 2019;22(3):305. doi:10.4103/jcd.jcd_13_19
Jablonski-Momeni A, Heinzel-Gutenbrunner M, Klein SM ari. C. In vivo performance of the VistaProof fluorescence-based camera for detection of occlusal lesions. Clin Oral Investig. 2014;18(7):1757-1762. doi:10.1007/s00784-013-1150-9
Guerra F, Mazur M, Rinaldo F, et al. New diagnostic technology and hidden pits and fissures caries. Senses Sci. 2015;2(1):20-23. https://www.researchgate.net/publication/274888894_New_diagnostic_technology_and_hidden_pits_and_fissures_caries. Accessed May 30, 2022.
Papageorgiou SN, Dimitraki D, Kotsanos N, Bekes K, van Waes H. Performance of pit and fissure sealants according to tooth characteristics: A systematic review and meta-analysis. J Dent. 2017;66(August):8-17. doi:10.1016/j.jdent.2017.08.004
Al-Jobair A, Al-Hammad N, Alsadhan S, Salama F. Retention and caries-preventive effect of glass ionomer and resin-based sealants: An 18-month-randomized clinical trial. Dent Mater J. 2017;36(5):654-661. doi:10.4012/dmj.2016-225
Suryasa, I. W., Rodríguez-Gámez, M., & Koldoris, T. (2022). Post-pandemic health and its sustainability: Educational situation. International Journal of Health Sciences, 6(1), i-v. https://doi.org/10.53730/ijhs.v6n1.5949
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