Changes in markers ferritin and c-reactive protein in patients with COVID-19 in Iraq
A case-control study
Keywords:
COVID-19, ferritin, C-reactive proteinAbstract
Background: According to the coronavirus virus resource center of Johns Hopkins Medicine, more than 75 million people are presently affected worldwide, SARS-CoV-2 infect host cells through the angiotensin-converting enzyme 2 (ACE2) receptor, which is found in a variety of human organs, the virus's entry into the bloodstream has resulted in the involvement of practically all of the body's organs. Aim: We have aimed to determine the roles of serum ferritin and CRP in different strata of patients with COVID-19 infection and to predict disease severity. Methods: A retrospective study was carried out after obtaining approval from the relevant Ethics Committee. Total number of 125 cases taken for study, admitted on a priority basis. Consecutive blood tests that included ferritin and CRP in the study period were reviewed. Patients diagnosed with SARS-CoV-2 infection in whom, serum ferritin and CRP had been analyzed at the time of admission were selected. For assessment of severity and behavior of the factors to be analyzed the COVID-19 patients were grouped into (mild),(moderate) and (severely ill) cases, factors analyzed in all groups and correlated,in December 27, 2020, to April 25, 2020. Results: For patients, the mean age was 51 years 64% were men.
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