Role of chlamydia trachomatis infection and anti-sperm antibody in male infertility

Abstract

There are many different factors that affect male infertility, including bacterial infections and immunological factors. The current study examined two factors that negatively affect male fertility. These factors include detection of C. trachomatis IgG antibodies and evaluation the presence of antisperm antibodies. Blood samples were collected from 63 infertile male with age of 33.37±0.86 years and 80 fertile male as control group with age 34.39±0.61, tests were conducted for them to detect for chlamydia trachomatis IgG antibody and presence of antisperm antibody measured by ELISA technique. C. trachomatis was demonstrated in the blood samples of (61,9%) infertile male were seropositive and all control samples were negative for anti chlamydia IgG. The seropositive for antisperm antibody was 20.6% in infertility male while seroposative for control group was negative this lead to suggest that chlamydia trachmatis and antibody against sperm play role in pathogensis of ferltlity.