Lipoprotein abnormalities in diabetic patients
Keywords:
lipoproteins, diabetes, obesity, InsulinAbstract
Objectives: To evaluate and compare blood glucose levels and lipid profile in diabetic vs healthy adults. Methodology: This descriptive cross sectional study was conducted from January 2021 to April 2021. The study samples were collected from Northwest General Hospital Peshawar. Sixty patients with diagnosed type 2 diabetes and an equal number of control subjects were included in this study. After the recruitment of subjects according to the inclusion criteria, subjects were divided into two cohorts; Patients with Diabetes (Group I N=60) and a Non-Diabetic Control Group (Control group N=60). Blood from the subjects was checked for glucose levels and lipid profile. Blood was taken and analysed at the Hospital Lab via Cobas 6000 analyser. Data was analysed using SPSS version 26.0 for MacBook Pro. T test was applied to the data and p value was kept at 0.05 for significance. Results: Fasting Blood Glucose (FBS) rise was statistically significant (p=0.03) with a mean and standard deviation (SD) of 161.21±46.31* for Group I and 79.29±18.56 for Group II with a Mean Difference (MD) of 81.92.
Downloads
References
Ahmad A, Khan AR, Raja ZA, Mustafa G. MEASUREMENT OF SERUM CHOLESTEROL AND TRIGLYCERIDE: EVALUATION IN PATIENTS WITH DIABETES; HYPERTENSION & CEREBROVASCULAR ACCIDENT IN SOUTH PUNJAB. The Professional Medical Journal. 2003 Jun 8;10(01):92-8.
Ayub R, Raza SS, Shafiullah JA, et al. Bacterial culture isolates from infected diabetic foot tissue specimens and their sensitivity to antimicrobial agents. J Med Sci 2016;24:273–7.
Chattanda, S.P. and Y.M. Mgonda, 2008. Diabetic dyslipidemia among diabetic patients attending specialized clinics in Dar es Salaam. Tanzania Med. J., 23(1): 08-11.
Chatterjee S, Khunti K, Davies MJ. Type 2 diabetes. Lancet. (2017) 389:2239–51. doi: 10.1016/S0140-6736(17)30058-2
Chen L, Magliano DJ, Zimmet PZ. The worldwide epidemiology of type 2 diabetes mellitus—present and future perspectives. Nature reviews endocrinology. 2012 Apr;8(4):228-36.
Gadi, R. And F.F. Samaha, 2007. Dyslipidemia in type 2 diabetes mellitus. Curr. Diab. Rep. Jun., 7(3): 228-34
Hidron, A.I., Edwards, J.R., Patel, J., Horan, T.C., Sievert, D.M., Pollock, D.A. and Fridkin, S.K., 2008. Antimicrobial-resistant pathogens associated with healthcare-associated infections: annual summary of data reported to the National Healthcare Safety Network at the Centers for Disease Control and Prevention, 2006 2007. Infection Control & Hospital Epidemiology, 29(11), pp.996 1011.
Khan, S.R., N. Ayub, S. Nawab and T.S. Shamsi, 2008. Triglyceride profile in dyslipidemia of type 2 diabetes mellitus. J. Coll. Physicians Surg. Pak., 18(5): 270-3.
Krishna, P., Roopakala and KM. Prasanna, 2005. Dyslipidemia in type 1 diabetes mellitus in the young. Int. J. Diab. Dev. Ctries, 25(4): 110-12.
Pang J, Chan DC, Barrett PH, Watts GF. Postprandial dyslipidaemia and diabetes: mechanistic and therapeutic aspects. Current opinion in lipidology. 2012 Aug 1;23(4):303-9.
Saeedi P, Petersohn I, Salpea P, Malanda B, Karuranga S, Unwin N, et al. Global and regional diabetes prevalence estimates for 2019 and projections for 2030 and 2045: Results from the International Diabetes Federation Diabetes Atlas, 9(th) edition. Diabetes Res Clin Pract. (2019) 157:107843. doi: 10.1016/j.diabres.2019.107843
Saxena, A. (2017). The impact of nutrition on the overall quality of life adolescent girls are living across the city of Kota. International Journal of Life Sciences, 1(1), 40–48. https://doi.org/10.21744/ijls.v1i1.21
Shamma, R. A., Hosni, Y. A., Hassan, M. M., Hassan, N. A., & Khedr, D. (2022). Role of optical coherence tomography angiography in early detection of retinal microvascular changes in adolescents with type 1 diabetes. International Journal of Health Sciences, 6(S4), 1337–1353. https://doi.org/10.53730/ijhs.v6nS4.6049
Suryasa, I. W., Rodríguez-Gámez, M., & Koldoris, T. (2021). The COVID-19 pandemic. International Journal of Health Sciences, 5(2), vi-ix. https://doi.org/10.53730/ijhs.v5n2.2937
Thambiah SC, Lai LC. Diabetic dyslipidaemia. Practical laboratory medicine. 2021 Aug 1;26:e00248.
Wang SH, Wang L, Zhou Y, Guo YJ, Yuan Y, Li FF, Huang Y, Xia WQ. Prevalence and control of dyslipidaemia among diabetic patients with microalbuminuria in a Chinese hospital. Diabetes and Vascular Disease Research. 2013 Mar;10(2):169-78.
Yang S, Yang G, Wu H, Kang L, Xiang J, Zheng P. microRNA-193-b impairs muscle growth in mouse models of type 2 diabetes by targeting the PDK1/Akt signalling pathway. Diabetology. 2021 Dec 16:1-9.
Zheng Y, Ley SH, Hu FB. Global aetiology and epidemiology of type 2 diabetes mellitus and its complications. Nat Rev Endocrinol. (2018) 14:88–98. doi: 10.1038/nrendo.2017.151
Published
How to Cite
Issue
Section
Copyright (c) 2022 International journal of health sciences
![Creative Commons License](http://i.creativecommons.org/l/by-nc-nd/4.0/88x31.png)
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Articles published in the International Journal of Health Sciences (IJHS) are available under Creative Commons Attribution Non-Commercial No Derivatives Licence (CC BY-NC-ND 4.0). Authors retain copyright in their work and grant IJHS right of first publication under CC BY-NC-ND 4.0. Users have the right to read, download, copy, distribute, print, search, or link to the full texts of articles in this journal, and to use them for any other lawful purpose.
Articles published in IJHS can be copied, communicated and shared in their published form for non-commercial purposes provided full attribution is given to the author and the journal. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
This copyright notice applies to articles published in IJHS volumes 4 onwards. Please read about the copyright notices for previous volumes under Journal History.