Polymorphism study of ATP1B1gene in hypertension with CKD  patients

Estabraq Yaarub Qahtan; Alaa Mohammad Hasson Al-Husseini

doi:10.53730/ijhs.v6nS8.12593

Polymorphism study of ATP1B1gene in hypertension with CKD patients

https://doi.org/10.53730/ijhs.v6nS8.12593

Authors

Estabraq Yaarub Qahtan
scie.bio.mas.20.7@qu.edu.iq
University of Al-Qadisiyah, College of Science, Department Of Biology, Iraq
Alaa Mohammad Hasson Al-Husseini University of Al-Qadisiyah, College of Science, Department Of Biology, Iraq

Keywords:

CKD, polymorphism, ATP1B1-gene, hypertension

Abstract

The present study aims to examine the genetic variation of the ATP1B1 gene concerning hypertension and chronic kidney disease CKD. (120 ) blood samples from participants were obtained and divided into three groups: a first group representing hypertensive patients (hyper), a second group representing Hypertensive CKD patients (hyper with CKD), and a third group representing a control group. DNA was extracted from all blood samples and then converted to cDNA and the ARMS-PCR technique was used to investigate the single nucleotide polymorphism (SNP) from the ATP1B1, genes. The result of this study investigated that SNP rs2901029 located in ATP1B1 is significant association with hypertension and CKD.

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Published

09-09-2022

How to Cite

Qahtan, E. Y., & Al-Husseini, A. M. H. (2022). Polymorphism study of ATP1B1gene in hypertension with CKD patients. International Journal of Health Sciences, 6(S8), 2866–2873. https://doi.org/10.53730/ijhs.v6nS8.12593

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Issue

Vol. 6 No. S8 (2022)

Section

Peer Review Articles

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