Age, lipid profile, testosterone, and prostate-specific antigen are predictors of erectile dysfunction in benign prostatic hyperplasia

https://doi.org/10.53730/ijhs.v6nS8.12661

Authors

  • Yeremia Gerald K Department of General Surgery, Faculty of Medicine, Udayana University, Sanglah Central General Hospital Denpasar, Bali, Indonesia, 80114
  • Gede Wirya Kusuma Duarsa Department of Urology, Faculty of Medicine, Udayana University, Sanglah Hospital Denpasar, Bali, Indonesia
  • Tjokorda Gde Bagus Mahadewa Department of Neurological Surgery, Faculty of Medicine, Udayana University, Sanglah Hospital Denpasar, Bali, Indonesia
  • I Nyoman Semadi Department of Thorax and Cardiovascular Surgery, Faculty of Medicine, Udayana University, Sanglah Hospital Denpasar, Bali Indonesia
  • I Wayan Niryana Department of Neurological Surgery, Faculty of Medicine, Udayana University, Sanglah Hospital Denpasar, Bali, Indonesia
  • Kadek Budi Santosa Department of Urology, Faculty of Medicine, Udayana University, Sanglah Hospital Denpasar, Bali, Indonesia

Keywords:

BPH, age, lipid profile, testosterone, PSA

Abstract

Erectile dysfunction (ED) is a condition with a higher prevalence in the elderly. A multinational survey of elderly men conducted in America, France, Germany, Italy, the Netherlands, Spain, and England showed an association with ED in >12,000 men aged 50-80. There is an increasing prevalence of hypercholesterolemia and hypertriglyceridemia in men with ED. Testosterone deficiency is the most common hormonal cause of ED and has recently been considered a global health problem associated with cardiovascular morbidity and mortality.Prostate-specific antigen (PSA)affects prostate volume associated with high testosterone. This study aims to determine age, lipid profile, testosterone, and PSA levels are predictors of ED incidence in BPH patients. Using analytic observational retrospective cohort design, years) with p=0.003, OR 0.2 (95% CI: 0, 07-0.58)which means that there is an increase of 0.2 times ED at age >60 years, lipid profile obtained p=0.016, OR 3.7 (CI95%: 1.22-11.45)which means an increase in cholesterol lipid profile total > 200 mg/dL/ TG > 150 mg/dL occurred 3.7 times ED, testosterone p=0.049 OR 3.5 (95% CI: 0.95-13.44) means low testosterone levels <193 pg/ml cause ED 3.5 times, and PSA p = 0.020, OR 0.3 (95% CI: 0.45-3.33) which means the level of >4 pg/mg causes ED 0.3 times. 

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Published

12-09-2022

How to Cite

Yeremia Gerald, K., Duarsa, G. W. K., Mahadewa, T. G. B., Semadi, I. N., Niryana, I. W., & Santosa, K. B. (2022). Age, lipid profile, testosterone, and prostate-specific antigen are predictors of erectile dysfunction in benign prostatic hyperplasia. International Journal of Health Sciences, 6(S8), 2339–2347. https://doi.org/10.53730/ijhs.v6nS8.12661

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