Multiple cerebral abscess caused by Klebsiella pneumonia on post tumor excision procedure

A case study

https://doi.org/10.53730/ijhs.v6nS8.12900

Authors

  • Adelheid Loraine Erensina Rumbiak Resident, Department of Neurology, Faculty of Medicine, Airlangga University - Dr. Soetomo Regional Public Hospital, Surabaya, Indonesia
  • Paulus Sugianto Department of Neurology Teaching Staff, Faculty of Medicine, Airlangga University - Dr. Soetomo Regional Public Hospital, Surabaya, Indonesia
  • Sita Setyowatie Department of Neurology Teaching Staff, Faculty of Medicine, Airlangga University - Dr. Soetomo Regional Public Hospital, Surabaya, Indonesia

Keywords:

cerebral abscess, post-operation cranial infection, Klebsiella pneumoniae

Abstract

A cerebral abscess can happen due to a nearby brain infection, other rare body parts spread, head injury and surgery procedures. Intracranial Klebsiella pneumoniae infection rarely happens and usually occurs in immunocompromised patients. We reported a case of a 50 years old immunocompetent woman with prior tumor excision that progressed to a cerebral abscess. The patient came to the ER unconscious with progressive right-side weakness, pus from previous operation scar, fever and headache since few days’ pre-admission. Laboratory findings were leukocyte 13.710, neutrophil 9%, CRP 7.6, and negative HIV test. The contrast CT scan resulted in a multiloculated ring enhancement left frontal lobe lesion sized 5.8x6.9x5.0 cm and perifocal oedema. Open craniotomy managed to evacuate ±40cc. The microbiology culture tested positive for Klebsiella pneumoniae. Despite proper technique and administration of prophylaxis antibiotics, severe infection that requires immediate intervention still develops in a small group of patients. Klebsiella pneumoniae is a common pathogen causing cerebral abscess in both immunocompromised and healthy patients. Pus drainage and immediate antibiotics administration improved all symptoms, including hemiparesis. This case highlights the importance of quick and right therapy.

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References

Brouwer, M. C., Tunkel, A. R., McKhann, G. M., & van de Beek, D. (2014). Brain abscess. The New England Journal of Medicine, 371(5), 447–456. https://doi.org/10.1056/NEJMra1301635

Carpenter, J., Stapleton, S., & Holliman, R. (2007). Retrospective analysis of 49 cases of brain abscess and review of the literature. European Journal of Clinical Microbiology & Infectious Diseases: Official Publication of the European Society of Clinical Microbiology, 26(1), 1–11. https://doi.org/10.1007/s10096-006-0236-6

Cavuşoglu, H., Kaya, R. A., Türkmenoglu, O. N., Colak, I., & Aydin, Y. (2008). Brain abscess: Analysis of results in a series of 51 patients with a combined surgical and medical approach during an 11-year period. Neurosurgical Focus, 24(6), E9. https://doi.org/10.3171/FOC/2008/24/6/E9

Dashti, S. R., Baharvahdat, H., Spetzler, R. F., Sauvageau, E., Chang, S. W., Stiefel, M. F., Park, M. S., & Bambakidis, N. C. (2008). Operative intracranial infection following craniotomy. Neurosurgical Focus, 24(6), E10. https://doi.org/10.3171/FOC/2008/24/6/E10

Kolegium Neurologi Indonesia. (2019). Modul Neuroinfeksi Program Pendidikan Dokter Spesialis Saraf.

Muzumdar, D., Jhawar, S., & Goel, A. (2011). Brain abscess: An overview. International Journal of Surgery (London, England), 9(2), 136–144. https://doi.org/10.1016/j.ijsu.2010.11.005

Ruiz-Barrera, M. A., Santamaría-Rodríguez, A. F., & Zorro, O. F. (2022). Brain abscess: A narrative review. Neurology Perspectives, 2(3), 160–167. https://doi.org/10.1016/j.neurop.2022.01.010

Sonneville, R., Ruimy, R., Benzonana, N., Riffaud, L., Carsin, A., Tadié, J.-M., Piau, C., Revest, M., Tattevin, P., & ESCMID Study Group for Infectious Diseases of the Brain (ESGIB). (2017). An update on bacterial brain abscess in immunocompetent patients. Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases, 23(9), 614–620. https://doi.org/10.1016/j.cmi.2017.05.004

Valentino A & Angraini GP. (2019). Abses Otak. Jurnal Ilmu Kedokteran, 13, 75–86.

Wang, B., Zhang, P., Li, Y., & Wang, Y. (2019). Klebsiella pneumoniae-induced multiple invasive abscesses: A case report and literature review. Medicine, 98(39), e17362. https://doi.org/10.1097/MD.0000000000017362

Winn, H. R. (Ed.). (2017). Neurological Surgery (Seventh edition). Elsevier.

Wu, C., Han, S., Baydur, A., & Lindgren, B. (2021). Klebsiella brain abscess in an immunocompetent patient: A case report. Journal of Medical Case Reports, 15(1), 44. https://doi.org/10.1186/s13256-020-02633-0

Zhao, J., Huo, T., Luo, X., Lu, F., Hui, S., & Yang, B. (2022). Klebsiella pneumoniae-related brain abscess and meningitis in adults: Case report. Medicine, 101(2), e28415. https://doi.org/10.1097/MD.0000000000028415

Published

21-09-2022

How to Cite

Rumbiak, A. L. E., Sugianto, P., & Setyowatie, S. (2022). Multiple cerebral abscess caused by Klebsiella pneumonia on post tumor excision procedure: A case study. International Journal of Health Sciences, 6(S8), 3591–3596. https://doi.org/10.53730/ijhs.v6nS8.12900

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Section

Peer Review Articles