To study the prevalence and severity of neutropenia in newly diagnosed HIV patients and their correlation with CD4 counts

https://doi.org/10.53730/ijhs.v6nS8.12956

Authors

  • Ram Kishan Jat Associate Professor, Department of Medicine, Mahatma Gandhi Medical College and Hospital, Jaipur, Rajasthan, India
  • Anil Kumar Panwar Associate Professor, Department of Medicine, Mahatma Gandhi Medical College and Hospital, Jaipur, Rajasthan, India
  • Shrikant Choudhary Assistant Professor, Department of Medicine, Mahatma Gandhi Medical College and Hospital, Jaipur, Rajasthan, India
  • Shivani Sharma Intern, Mahatma Gandhi Dental College, Mahatma Gandhi University of Medical Sciences & Technology, Jaipur, Rajasthan, India
  • Jai Prakash Yogi Assistant Professor, Department of Biochemistry, Mahatma Gandhi Medical College and Hospital, Jaipur, Rajasthan, India
  • Ankur Kumar Bichhwaliya Assistant Professor, Department of Anatomy, Mahatma Gandhi Medical College and Hospital, Jaipur, Rajasthan, India

Keywords:

prevalence, neutropenia, HIV, CD4 counts

Abstract

Background: The incidence as well as the severity of haematological complications increases as the HIV disease progresses. Neutropenia usually occurs as HIV disease progresses and is an independent risk factor for bacterial infection in advanced HIV disease. Method: this observational study was carried out in Department of Medicine, J.L.N. Medical College and hospital, Ajmer. 100 patients were selected for study and were examined and underwent routine investigations. Results: In this study the frequency and severity of leucopenia increases with declining CD4 counts and has got significant impact on clinical outcome.

Downloads

Download data is not yet available.

References

Aboulafia DM, Mitsuyasu RT. Hematologic abnormalities in AIDS. Hematol Oncol Clin North Am. 1991 Apr;5(2):195-214.PMID: 2022589.

Alexandra M, Levine, Karim R, Mack W. Neutropenia in HIV data from the women's interagency HIV study. Arch Intern Med Feb 27,2006; 166:405-10.

Gaidano G, Carboni A. AIDS related lymphomas from pathogenesis to pathology. Br J Haematol 1995; 90:235-243.

Henry DH, Hoxie JA: Hematological manifestation of AIDS in Hoffman R; Sunz Shott! SS et al: Editors. Hematology basis Principals & Practices, 4° ed. Philadelphia, Churchell Livingstone, 2005.

Karcher DS. Clinically unsuspected Hodgkin's disease presenting initially in the bone marrow of patients infected with the human immunodeficiency virus. Cancer 1993 Oct Feb; 71(4):1235-38.

Scadden DT. Hematologic disorders and growth factor support in HIV infection. Hematol Oncol Clin North Am 1996 Oct; 10(5):1149-61.

Suresh Venkata Satya Attili, V. P. Singh, Madhukar Rai; Hematological manifestation of HIV patients in relation to CD 4 counts- a hospital cohort from Varanasi; Turk J Hematol 2008;25:13-19.

Treacy M, Lai L, Costella C, Clark A. Peripheral blood and bone marrow abnormalities in patients with HIV related diseases. Br J Haematol 1987; 65:289-294.

Vanderlich J, Lange MA, Voss JJE, et al. Autoimmunity against blood cells in human immunodeficiency virus infection. Br J Haematol 1987; 67:109-14.

Published

23-09-2022

How to Cite

Jat, R. K., Panwar, A. K., Choudhary, S., Sharma, S., Yogi, J. P., & Bichhwaliya, A. K. (2022). To study the prevalence and severity of neutropenia in newly diagnosed HIV patients and their correlation with CD4 counts. International Journal of Health Sciences, 6(S8), 3782–3793. https://doi.org/10.53730/ijhs.v6nS8.12956

Issue

Section

Peer Review Articles