The prevalence of abnormal lab results in pediatric patients at a hospital outpatient clinic
A cross-sectional study
Keywords:
birth abnormalities, maternal risks, GUT, CNSAbstract
Objective: Examining the prevalence of different forms of birth defects and identifying their causes. Study design: Study Design: A cross-sectional study with retrospective analysis for causes. Place and duration of study: Department of Neurosurgery MMC hospital Mardan from 05 Jan 2021 to October 2021. Methods: All gender-neutral newborns seeking well-child care department of Neurosurgery MMC Mardan. Participating subjects were enlisted, and data were input and analyzed using SPSS v 22.0, regardless of whether they had received any prenatal care, or vaccinations, or were born with any observable abnormalities. Results: In our analysis of 497 individuals, 23% exhibited CNS congenital abnormalities. 47 children (9%) had gastrointestinal malformations, 111 had musculoskeletal anomalies, 42 had cardio-vascular anomalies, and 181 had genito-urinary anomalies. Extreme maternal age (less than 74 and more than 42 at conception), consanguinity, preterm deliveries, maternal smoking, and family history of birth abnormalities were similarly distributed across patients with diverse malformations. Genito-urinary abnormalities are the most common, followed by CNS and musculoskeletal anomalies.
Downloads
References
Al Bu Ali WM, Balaha MH, Al Moghannum MS, Hashim I. Risk factors and birth prevalence of birth defects and inborn errors of metabolism in Al Ahsa, Saudi Arabia. Pan Afric Med J 2011; 8:14-7.
Babu RS, Pasula S. Frequency of Foetal Anomalies in a Tertiary Care Centre. J Clinic Diagnosis Research 2013; 7(7): 1276-1279.
Gul F, Jabeen M, Khan AS. Frequency of congenital malformations and associated risk factors at Liaqat Memorial Hospital, Kohat. Khyber Med Univ J 2012; 4(3): 119-124.
Huisman T. Intracranial hemorrhage: ultrasound, CT, and MRI findings. Eur Radiol 2005; 15: 434-440.
Jordan LC, Kleinman JT, Hillis AE. Intracerebral hemorrhage volume predicts poor neurologic outcomes in children. Stroke 2009; 40: 1666-1671.
Khan IA, Wahab S, Khan RA, Ullah E, Ali M. Neonatal intracranial ischemia and hemorrhage: Role of cranial sonography and CT scanning. J Korean Neurosurg Soc 2010; 47: 89-94.
Martínez JL, Díaz R, Sánchez E. Accidente vascularencefálico en reciénnacidos de término y pretérminotardíos. Rev Chil Pediatr 2009; 80: 54-59.
Masood SN, Jamil N, Mumtaz SN, Masood MF, Muneer S. Congenital malformations in newborns of consanguineous and non-consanguineous parents. Pak J Med Sci 2011;27(1):1-5.
Mattson SN, Schoenfeld AM, Riley EP. Teratogenic effects of alcohol on brain and behavior. Alcohol Res Health 2001; 25:185-9.
Ou-Yang M, Huang C, Huang H, Chung M, Chen C, et al. Clinical manifestations of symptomatic intracranial hemorrhage in term neonates: 18 years of experience in a medical center. Pediatr Neonatal 2010; 51: 208-213.
Raza MZ, Sheikh A, Ahmed SS, Ali S, Naqvi SMA. Risk factors associated with birth defects at a tertiary care center in Pakistan. Italian J Pedia 2012; 38:68 (http://www.ijponline.net/content/38/1/68.
Rooks VJ, Eaton JP, Ruess L, Petermann GW, Keck-Wherley J, et al. Prevalence and evolution of intracranial hemorrhage in symptomatic term infants. Rooks 2008; 29: 1082-1089.
Sirgiovanni I, Avignone S, Groppo M, Bassi L, Passera S, et al. Intracranial hemorrhage: An incidental finding at magnetic resonance imaging in a cohort of late-term and term infants. Pediatr Radiol 2014; 44: 289-296.
Smith C. Intracranial hemorrhage in infants. Current Diagnostic Pathology 2006; 12: 184-190.
Wezel G, Leijser LM, Bruine FT, Steggerda SJ, van der Grond J, et al. Magnetic resonance imagign of the brain in new-born infants: practical aspects. Early Human Development 2009; 85: 85-92.
Published
How to Cite
Issue
Section
Copyright (c) 2022 International journal of health sciences
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Articles published in the International Journal of Health Sciences (IJHS) are available under Creative Commons Attribution Non-Commercial No Derivatives Licence (CC BY-NC-ND 4.0). Authors retain copyright in their work and grant IJHS right of first publication under CC BY-NC-ND 4.0. Users have the right to read, download, copy, distribute, print, search, or link to the full texts of articles in this journal, and to use them for any other lawful purpose.
Articles published in IJHS can be copied, communicated and shared in their published form for non-commercial purposes provided full attribution is given to the author and the journal. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
This copyright notice applies to articles published in IJHS volumes 4 onwards. Please read about the copyright notices for previous volumes under Journal History.
