Perinatal asphyxia and the risk of hypoxic ischemic encephalopathy
A cross-sectional study
Keywords:
Asphyxia, Hypoxic, Ischemic, Encephalopathy, PerinatalAbstract
Background: Neonate-onset encephalopathy has a wide range of clinical presentations. Premature or late birth (defined as occurring before or after 35 weeks of gestation) and early-onset neurological impairments are linked to this condition. The patient may have a loss of consciousness, convulsions, difficulty breathing, delayed or halted respiration, slowed or stopped reflexes, and depressed tone. The purpose of this research was to determine the incidence of hypoxic ischemic encephalopathy (HIE) in patients diagnosed with perinatal asphyxia in a tertiary care hospital. Materials and methods: The GKMC/BKMC Hospital in Sawabi, Pakistan, conducted this cross-sectional research there. During the time period of July 1, 2021, to December 31, 2021, researchers acquired information. Eighty newborns with perinatal hypoxia were included in the research. Hypoxic ischemic encephalopathy screening criteria were applied to each infant. Results: In this study, ages were between 1 and 10 days old, with average being 2.5371.28 days. The average gestational age was 37.6811.24 weeks, and the average birth weight was 3.2750.35 kg. Vaginal deliveries accounted for 75% of all births, whereas caesarean sections were performed for just 25%. Hypoxic ischemic encephalopathy affected 8 people. Patients accounting for 11% of the total.
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Lee AC, Kozuki N, Blencowe H, Vos T, Bahalim A, Darmstadt GL, et al. Intrapartum-related neonatal encephalopathy incidence and impairment at regional and global levels for 2010 with trends from 1990. Pediatr Res. 2013;74(1):50-72. doi: 10.1038/pr.2013.206.
McIntyre S, Nelson K, Mulkey SB, Lechpammer M, Molloy E, Badawi N, et al., editors.
Neonatal encephalopathy: Focus on epidemiology and underexplored aspects of etiology. Seminars in Fetal and Neonatal Medicine; 2021: Elsevier. doi: 10.1016/j.siny.2021.101265.
Bachu S, Hariharan G. Does fluid balance affect neurodevelopmental outcomes in hypoxic‐ ischaemic encephalopathy? 2021. doi.org/10.1111/apa.15992
Ivain P, Montaldo P, Khan A, Elagovan R, Burgod C, Morales MM, et al. Erythropoietin monotherapy for neuroprotection after neonatal encephalopathy in low-to-middle incomecountries: a systematic review and meta-analysis. J Perinatol. 2021:1-7. doi.org/10.1038/s41372-021-01132-4
Buchiboyina A, Yip CSA, Mehta S. Cooling infants with mild hypoxic ischaemic encephalopathy-Do we have the evidence? The Journal of Maternal-Fetal & Neonatal Medicine. 2021:1-3. doi: 10.1002/14651858.CD003311.pub3.
Gumus H, Demir A. An Evaluation of Risk Factors in Cases of Perinatal Asphyxia. Journal of Clinical & Experimental Investigations. 2021;12(1). doi.org/10.29333/jcei/9563
Gebregziabher GT, Hadgu FB, Abebe HT. Prevalence and associated factors of perinatal asphyxia in neonates admitted to ayder comprehensive specialized hospital, Northern Ethiopia: a cross-sectional study. Int J Pediatr. 2020;2020. doi: 10.1155/2020/4367248.
Antonucci R, Porcella A, Pilloni MD. Perinatal asphyxia in the term newborn. Journal of Pediatric and Neonatal Individualized Medicine (JPNIM). 2014;3(2):e030269-e. doi.org/10.7363/030269
Ezenwa BN, Olorunfemi G, Fajolu I, Adeniyi T, Oleolo-Ayodeji K, Kene-Udemezue B, et al. Trends and predictors of in-hospital mortality among babies with hypoxic ischaemic encephalopathy at a tertiary hospital in Nigeria: A retrospective cohort study. PLoS One. 2021;16(4):e0250633. doi: 10.1371/journal.pone.0250633.
Lally PJ, Price DL, Pauliah SS, Bainbridge A, Kurien J, Sivasamy N, et al. Neonatal encephalopathic cerebral injury in South India assessed by perinatal magnetic resonance biomarkers and early childhood neurodevelopmental outcome. PLoS One. 2014;9(2):e87874. doi: 10.1371/journal.pone.0087874.
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