Prevalence of depression in patients on hemodialysis

https://doi.org/10.53730/ijhs.v7nS1.14149

Authors

  • Mazharulhaq Assistant Professor Nephrology, Institute of Kidney Diseases Hayatabad, Peshawar, Pakistan
  • Kashif Rafique Consultant Nephrologist, Nephrology Shifa International Hospital, Islamabad, Pakistan
  • Zahid Ahmad Assistant Consultant Nephrology, Quaid E Azam International Hospital, Islamabad, Pakistan
  • Adil Umer Khan Associate Professor Community Medicine, Bakhtawar Amin Medical College, Multan, Pakistan
  • Ayesha Arshad Consultant Nephrology, PAF Hospital, Islamabad, Pakistan
  • Kulsoom Ilyas Nephrologist / Medical Specialist, Doctors Plus Pharmacy and Diagnostics, Sector A ,Bahria Enclave, Islamabad, Pakistan

Keywords:

depression, chronic kidney disease, hemodialysis

Abstract

Objective: To determine the prevalence of depression in patients undergoing hemodialysis. Study Design: Cross-sectional study. Place and Duration: Institute of Kidney Diseases Hayatabad, Peshawar and PAF Hospital Islamabad for the duration from December 2021 to May 2022. Methodology: Two hundred and twenty patients on hemodialysis of either gender with ages 25-70 years were enrolled. Detailed demographics were recorded after taking informed written consent. Patients' Health Questionnaire-9 (PHQ-9) questions were used to determine the frequency of depression. Severity of depression was also examined. Data was analyzed by SPSS 24.0. Results: There were 135 (61.36%) males while 85 (38.64%) patients were females. Mean age of patients was 46.85±12.38 years. Mean time duration of hemodialysis was 5.25±2.46 years. Depression was found in 160 (72.73%) patients, among them 30 (13.64%) patients had mild, 75 (34.09%) had moderate and 55 (25%) had severe depression. Patients on hemodialysis less than 5 years found more depressive as compared to >5 years. (p-value <0.05). Conclusion: It is concluded that the prevalence of depression in patients of hemodialysis was high.

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References

Collaboration GCKD. Global, regional, and national burden of chronic kidney disease, 1990-2017: a systematic analysis for the global burden of disease study 2017. Lancet. 2020;395(10225):933–733.

Cho Y, Bello AK, Levin A, et al. Peritoneal dialysis use and practice patterns: an international survey study. Am J Kidney Dis. 2021;77(3):315–325.

Htay H, Bello AK, Levin A, et al. Hemodialysis use and practice patterns: an international survey study. Am J Kidney Dis. 2021;77(3):326–335.

Palmer S, Vecchio M, Craig JC, et al. Prevalence of depression in chronic kidney disease: systematic review and meta-analysis of observational studies. Kidney Int. 2013;84(1):179–191.

Gerogianni G, Lianos E, Kouzoupis A, et al. The role of socio-demographic factors in depression and anxiety of patients on hemodialysis: an observational cross-sectional study. Int Urol Nephrol. 2018;50(1):143–154.

Palmer SC, Vecchio M, Craig JC, et al. Association between depression and death in people with CKD: a meta-analysis of cohort studies. Am J Kidney Dis. 2013;62(3):493–505.

Farrokhi F, Abedi N, Beyene J, et al. Association between depression and mortality in patients receiving long-term dialysis: a systematic review and meta-analysis. Am J Kidney Dis. 2014;63(4):623–635.

Shimizu U, Aoki H, Sakagami M, et al. Walking ability, anxiety and depression, significantly decrease EuroQol 5-Dimension 5-Level scores in older hemodialysis patients in Japan. Arch Gerontol Geriatr. 2018;78(5):96–100.

Chen CK, Tsai YC, Hsu HJ, et al. Depression and suicide risk in hemodialysis patients with chronic renal failure. Psychosomatics. 2010;51(6):528–534.

Martiny C, de Oliveira e Silva AC, Neto JP, et al. Factors associated with risk of suicide in patients with hemodialysis. Compr Psychiatry. 2011;52(5):465–468.

De Berardis D, Fornaro M, Valchera A, et al. Eradicating suicide at its roots: preclinical bases and clinical evidence of the efficacy of ketamine in the treatment of suicidal behaviors. IJMS. 2018;19(10):2888–2909.

Orsolini L, Latini R, Pompili M, et al. Understanding the complex of suicide in depression: from research to clinics. Psychiatry Investig. 2020;17(3):207–221.

Watnick S, Kirwin P, Mahnensmith R, Concato J. The prevalence and treatment of depression among patients starting dialysis Am J Kidney Dis. 2003;41:105–10

Farrokhi F, Abedi N, Beyene J, Kurdyak P, Jassal SV. Association between depression and mortality in patients receiving long-term dialysis: A systematic review and meta-analysis Am J Kidney Dis. 2014;63:623–35

McAdams-DeMarco MA, Tan Jw, Salter ML, Gross A, Meoni LA, Jaar BG, et al Frailty and cognitive function in incident hemodialysis patients Clin J Am Soc Nephrol. 2015;10:2181–9.

King-Wing Ma T, Kam-Tao Li P. Depression in dialysis patients Nephrology (Carlton). 2016;21:639–46.

Dziubek W, Kowalska J, Kusztal M, Rogowski L, Golebiowski T, Nikifur M, et al The level of anxiety and depression in dialysis patients undertaking regular physical exercise training-A preliminary study Kidney Blood Press Res. 2016;41:86–98.

Khan, A., Khan, A.H., Adnan, A.S. et al. Prevalence and predictors of depression among hemodialysis patients: a prospective follow-up study. BMC Public Health 19, 531 (2019).

AlDukhayel. Prevalence of depressive symptoms among hemodialysis and peritoneal dialysis patients. International Journal of Health Sciences, QassimUniversity.2015 9(1):10-16.

Eman Nagy, Samar Tharwat, Abdelrahman Mohammed Elsayed, Shimaa Shabaka, Mohammed Kamal Nassar, MO841: Anxiety and Depression in Maintenance Hemodialysis Patients: Prevalence and Their Effects on Health-Related Quality of Life, Nephrology Dialysis Transplantation, Volume 37, Issue Supplement_3, May 2022, gfac083.023, https://doi.org/10.1093/ndt/gfac083.023.

Stasiak CE, Bazan KS, Kuss RS, Schuinski AF, Baroni G. Prevalence of anxiety and depression and its comorbidities in patients with chronic kidney disease on hemodialysis and peritoneal dialysis J Bras Nefrol. 2014;36:325–31.

Elkheir, Habab Khalid1; Wagaella, Arwa Siddig2; Badi, Safaa3; Khalil, Abbas4; Elzubair, Tarig Hassan5; Khalil, Atif6; Ahmed, Mohamed H.7,. Prevalence and risk factors of depressive symptoms among dialysis patients with end-stage renal disease (ESRD) in Khartoum, Sudan: A cross-sectional study. Journal of Family Medicine and Primary Care: July 2020 - Volume 9 - Issue 7 - p 3639-3643.

Othayq A, Aqeeli A. Prevalence of depression and associated factors among hemodialyzed patients in Jazan area, Saudi Arabia: a cross-sectional study. Ment Illn. 2020;12(1):1-5. doi: 10.1108/MIJ-02-2020-0004. Epub 2020 May 20. PMID: 32742625; PMCID: PMC7370954.

Khadka S, Adhikari R, Paudel T. Depression Among Chronic Kidney Diseases Patients Receiving Hemodialysis. Journal of Karnali Academy of Health Sciences 2020;3(2): 73-79.

de Alencar SBV, Dias LA, Dias VA, de Lima FM, Montarroyos UR, de Petribú KCL. Quality of life may be a more valuable prognostic factor than depression in older hemodialysis patients. Quality of Life Research.. 2020;1-10.

de Brito DCS, Machado EL, Reis IA, de Freitas do Carmo LP, Cherchiglia ML. Depression and anxiety among patients undergoing dialysis and kidney transplantation: A cross-sectional study. Sao Paulo Medical Journal. 2019;137(2):137– 47.

Published

12-04-2023

How to Cite

Mazharulhaq, Rafique, K., Ahmad, Z., Khan, A. U., Arshad, A., & Ilyas, K. (2023). Prevalence of depression in patients on hemodialysis. International Journal of Health Sciences, 7(S1), 41–48. https://doi.org/10.53730/ijhs.v7nS1.14149

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