Association between Vitamin D, P1NP, and BMD as major indicators of bone health in local population of Pakistan
Keywords:
Vitamin D, P1NP, BMD, bone healthAbstract
It is commonly known that the Pakistani population has inadequate vitamin D levels, but its effects on bone health and the level of N-terminal peptide of procollagen (PINP) have not yet determined. The aim of the research work was to check the vitamin D grade of exercisers and non-exercisers and examine how it related to P1NP concentration, a biochemical marker of bone production, and bone mineral density. A random sampling technique was used to select males and females who were staying in neighborhood. They were between the ages of 18 and 35 years. 92 people of Pakistani ancestry made up the total population. With 46 people, Group A was a non-exercising control group. Group B has 46 individuals in it. Both of these groups were gathered for the data analysis. BMD, procollagen type-1 amino-terminal pro-peptide, calciferol, and other biological indicator of bone remodeling were measured in serum. (P1NP). Using broadband ultrasound attenuation, the quality of the bones was evaluated. Before training, the total 25(OH)D serum were considerably less in non-exercising group than they were during or after training. (Mean: 0.4992, Standard Deviation: -1.6075; P 0001).
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Bess Dawson-Hughes, M., Drezner, M., Rosen, C., & Mulder, J. (2021). Vitamin D deficiency in adults: Definition, clinical manifestations, and treatment. In: UpToDate.
Brukner, P. (1998). Stress fractures of the upper limb. Sports Medicine, 26, 415-424.
Cashman, K. D., van den Heuvel, E. G., Schoemaker, R. J., Prévéraud, D. P., Macdonald, H. M., & Arcot, J. (2017). 25-Hydroxyvitamin D as a biomarker of vitamin D status and its modeling to inform strategies for prevention of vitamin D deficiency within the population. Advances in nutrition, 8(6), 947-957.
Gariballa, S., Yasin, J., Abluwi, G., & Al Essa, A. (2022). Vitamin D deficiency associations with metabolic, bone turnover and adverse general health markers in community free living adults. BMC Endocrine Disorders, 22(1), 1-10.
Ginty, F., Cavadini, C., Michaud, P., Burckhardt, P., Baumgartner, M., Mishra, G., & Barclay, D. (2004). Effects of usual nutrient intake and vitamin D status on markers of bone turnover in Swiss adolescents. European journal of clinical nutrition, 58(9), 1257-1265.
Grønborg, I. M., Tetens, I., Andersen, E. W., Kristensen, M., Larsen, R. E., Tran, T. L., & Andersen, R. (2019). Effect of vitamin D fortified foods on bone markers and muscle strength in women of Pakistani and Danish origin living in Denmark: a randomised controlled trial. Nutrition journal, 18(1), 1-12.
Kimball, S., Fuleihan, G. E.-H., & Vieth, R. (2008). Vitamin D: a growing perspective. Critical reviews in clinical laboratory sciences, 45(4), 339-414.
Koivula, M.-K., Risteli, L., & Risteli, J. (2012). Measurement of aminoterminal propeptide of type I procollagen (PINP) in serum. Clinical biochemistry, 45(12), 920-927.
Nair, S., Bhadricha, H., Hatkar, S., Kadam, S. S., Patil, A., Surve, S., . . . Desai, M. (2020). Effect of vitamin D levels on bone remodeling in healthy women. International Journal of Endocrinology and Metabolism, 18(2).
Papanastasiou, L., Gravvanis, C., Tournis, S., Markou, A., Giagourta, I., Lymperopoulos, K., & Kounadi, T. (2020). Effectiveness of intramuscular ergocalciferol treatment in a patient with osteomalacia and insufficiency fractures due to severe vitamin D deficiency after bariatric surgery. Journal of Musculoskeletal & Neuronal Interactions, 20(2), 291.
Pazirandeh, S., & Burns, D. L. (2014). Overview of vitamin D. Waltham, MA: UpToDate.
Shetty, S., Kapoor, N., Bondu, J. D., Thomas, N., & Paul, T. V. (2016). Bone turnover markers: Emerging tool in the management of osteoporosis. Indian journal of endocrinology and metabolism, 20(6), 846.
Suwija, N., Suarta, M., Suparsa, N., Alit Geria, A.A.G., Suryasa, W. (2019). Balinese speech system towards speaker social behavior. Humanities & Social Sciences Reviews, 7(5), 32-40. https://doi.org/10.18510/hssr.2019.754
Theintz, G., Buchs, B., Rizzoli, R., Slosman, D., Clavien, H., Sizonenko, P., & Bonjour, J.-P. (1992). Longitudinal monitoring of bone mass accumulation in healthy adolescents: evidence for a marked reduction after 16 years of age at the levels of lumbar spine and femoral neck in female subjects. The Journal of clinical endocrinology & metabolism, 75(4), 1060-1065.
Valle Coca, M. (2017). The relationship between Vitamin D levels and the body mass index (BMI) in a population cohort.
Wheater, G., Elshahaly, M., Tuck, S. P., Datta, H. K., & van Laar, J. M. (2013). The clinical utility of bone marker measurements in osteoporosis. Journal of translational medicine, 11, 1-14.
Widana, I.K., Dewi, G.A.O.C., Suryasa, W. (2020). Ergonomics approach to improve student concentration on learning process of professional ethics. Journal of Advanced Research in Dynamical and Control Systems, 12(7), 429-445.
Widana, I.K., Sumetri, N.W., Sutapa, I.K., Suryasa, W. (2021). Anthropometric measures for better cardiovascular and musculoskeletal health. Computer Applications in Engineering Education, 29(3), 550–561. https://doi.org/10.1002/cae.22202
Zarei, A., Morovat, A., Javaid, K., & Brown, C. P. (2016). Vitamin D receptor expression in human bone tissue and dose-dependent activation in resorbing osteoclasts. Bone research, 4(1), 1-10.
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